Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | CASP1 | P29466 | 1/20 | 0.53 |
| ▸ | CASP7 | P55210 | 1/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.51 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9904096 | 0.85 | POLB (0.53) | POLBHSD17B10ALDH1A1CYP3A4CASP1 | |
| SCHEMBL3177066 | 0.79 | PDE4A (0.54) | ADORA2A | |
| Water SCHEMBL28799658 | 0.79 | PDE2A (0.60) | POLBHSD17B10ALDH1A1CYP3A4CASP1 | |
| SCHEMBL3175450 | 0.78 | PDE4A (0.50) | ADORA2A | |
| SCHEMBL461786 | 0.77 | PDE2A (0.62) | POLBHSD17B10ALDH1A1CYP3A4CASP1 | |
| SCHEMBL11218297 | 0.75 | POLB (0.50) | POLBHSD17B10ALDH1A1CYP3A4CASP1 | |
| Water SCHEMBL7315528 | 0.75 | ADORA2B (0.70) | HSD17B10ALDH1A1ADORA2AADORA2BCYP1A2 | |
| SCHEMBL7325359 | 0.75 | ADORA2B (0.70) | HSD17B10ALDH1A1ADORA2AADORA2BCYP1A2 | |
| SCHEMBL3194191 | 0.75 | ADORA2A (0.59) | POLBHSD17B10ALDH1A1CYP3A4CASP1 | |
| SCHEMBL1400610 | 0.75 | ADORA2B (0.57) | POLBHSD17B10ALDH1A1CYP3A4CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1491591-B1 | New fluorescence cyanine labels containing a sulfamido linker arm | VISEN MEDICAL INC (US) | 2009-07-01 | — | — | EP | disclosed |
| EP-1065250-B1 | New fluorescent cyanine labels containing a sulfamido linker arm | VISEN MEDICAL INC (US) | 2004-12-08 | — | — | EP | disclosed |
| US-6448008-B1 | IMMUNOLOGICAL BINDING REAGENT LABELLED WITH A FLUORESCENT COMPOUND AND METHOD OF ASSAYING AN ANALYTE IN A SAMPLE COMPRISING CONTACTING A NUCLEIC ACID PROBE OR AN IMMUNOLOGICALLY BINDING REAGENT LABELLED WITH A FLUORESCENT | INNOSENSE, S.R.L. (IT) | 2002-09-10 | — | — | US | disclosed |
| EP-1173433-A1 | CYANOPYRROLES AS PROGESTERONE RECEPTOR AGONISTS | American Home Products Corporation (US) | 2002-01-23 | — | — | EP | disclosed |
| EP-1065250-A1 | New fluorescent cyanine labels containing a sulfamido linker arm | Innosense S.r.l. (IT) | 2001-01-03 | — | — | EP | disclosed |
| WO-2000066581-A1 | CYANOPYRROLES AS PROGESTERONE RECEPTOR AGONISTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-11-09 | — | — | WO | disclosed |