Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.82 |
| ▸ | TAS1R1 | Q7RTX1 | 4/20 | 0.82 |
| ▸ | TAS1R2 | Q8TE23 | 4/20 | 0.82 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | MLYCD | O95822 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL705624 | 0.90 | TAS1R3 (1.00) | TAS1R3TAS1R1TAS1R2HTTSMN1; SMN2 | |
| SCHEMBL24598454 | 0.84 | TAS1R3 (0.61) | TAS1R3TAS1R1TAS1R2HTTSMN1; SMN2 | |
| SCHEMBL20662856 | 0.83 | TAS1R3 (0.79) | TAS1R3TAS1R1TAS1R2HTTSMN1; SMN2 | |
| SCHEMBL18182635 | 0.76 | HTT (0.61) | TAS1R3TAS1R1TAS1R2HTTSMN1; SMN2 | |
| SCHEMBL24687425 | 0.75 | HTT (0.67) | TAS1R3TAS1R1TAS1R2HTTSMN1; SMN2 | |
| SCHEMBL15735617 | 0.75 | TAS1R3 (0.50) | TAS1R3TAS1R1TAS1R2HTTSMN1; SMN2 | |
| SCHEMBL21165338 | 0.74 | TAS1R3 (0.73) | TAS1R3TAS1R1TAS1R2HTTSMN1; SMN2 | |
| SCHEMBL5051925 | 0.73 | RAB9A (0.49) | TAS1R3TAS1R1TAS1R2HTTSMN1; SMN2 | |
| SCHEMBL15734359 | 0.73 | TAS1R3 (0.49) | TAS1R3TAS1R1TAS1R2HTTSMN1; SMN2 | |
| SCHEMBL15734193 | 0.73 | TAS1R3 (0.49) | TAS1R3TAS1R1TAS1R2HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090047379-A1 | Benzamide Compounds Useful as High Potency Sweet Taste Enhancers | DEWIS MARK L | 2009-02-19 | — | — | US | disclosed |
| US-20090047379-A1 | Benzamide Compounds Useful as High Potency Sweet Taste Enhancers | DEWIS MARK L | 2009-02-19 | — | — | US | disclosed |
| US-20090047379-A1 | Benzamide Compounds Useful as High Potency Sweet Taste Enhancers | DEWIS MARK L | 2009-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090047379-A1 | Benzamide Compounds Useful as High Potency Sweet Taste Enhancers | TAS2R10, TAS2R50, TAS2R8 | TAS1R3 27/4885TAS1R1 23/4885TAS1R2 11/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.