Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.41 |
| ▸ | MAOB | P27338 | 8/20 | 0.40 |
| ▸ | MAOA | P21397 | 7/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | TOP1 | P11387 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15069704 | 0.88 | ALOX5 (0.51) | HRH3MAOBMAOAALOX5LMNA | |
| SCHEMBL8751709 | 0.76 | TSHR (0.64) | MAOBMAOAALOX5LMNACYP1A2 | |
| SCHEMBL4173550 | 0.76 | FYN (0.32) | — | |
| SCHEMBL28316590 | 0.74 | HRH3 (0.52) | HRH3MAOBMAOAALOX5CA2 | |
| SCHEMBL3158759 | 0.73 | TSHR (0.64) | MAOBMAOAALOX5LMNACYP1A2 | |
| SCHEMBL21126508 | 0.72 | GSTP1 (0.49) | MAOBMAOAALOX5LMNACYP1A2 | |
| SCHEMBL14956431 | 0.72 | TSHR (0.32) | TSHR | |
| SCHEMBL9797450 | 0.72 | TSHR (0.52) | MAOBMAOALMNACYP1A2PTGS1 | |
| SCHEMBL197717 | 0.71 | TSHR (0.56) | MAOBMAOAALOX5LMNACYP1A2 | |
| SCHEMBL9797456 | 0.70 | LMNA (0.74) | MAOBMAOALMNACYP1A2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2011781-B1 | PROCESS FOR PRODUCTION OF INDENE DERIVATIVE, AND INTERMEDIATE FOR PRODUCTION OF THE DERIVATIVE | MICROBIOPHARM JAPAN CO LTD (JP) | 2014-03-05 | — | — | EP | disclosed |
| US-20120289723-A1 | METHOD FOR PREPARING INDENE DERIVATIVES, AND INTERMEDIATES FOR PREPARATION OF DERIVATIVES | MICROBIOPHARM JAPAN CO., LTD (JP) | 2012-11-15 | — | — | US | disclosed |
| US-20090177002-A1 | Method For Preparing Indene Derivatives, And Intermediates For Preparation Of Derivatives | MICROBIOPHARM JAPAN CO., LTD. (JP) | 2009-07-09 | — | — | US | disclosed |
| EP-2011781-A1 | PROCESS FOR PRODUCTION OF INDENE DERIVATIVE, AND INTERMEDIATE FOR PRODUCTION OF THE DERIVATIVE | MERCIAN CORPORATION (JP) | 2009-01-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090177002-A1 | Method For Preparing Indene Derivatives, And Intermediates For Preparation Of Derivatives | CYP2R1, CYP24A1, VDR | HRH3 819/4885MAOB 603/4885MAOA 1008/4885 |
| US-20120289723-A1 | METHOD FOR PREPARING INDENE DERIVATIVES, AND INTERMEDIATES FOR PREPARATION OF DERIVATIVES | CYP2R1, CYP24A1, VDR | HRH3 819/4885MAOB 603/4885MAOA 1008/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.