Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | TYMP | P19971 | 1/20 | 0.42 |
| ▸ | TYMS | P04818 | 2/20 | 0.40 |
| ▸ | BCHE | P06276 | 2/20 | 0.38 |
| ▸ | RNASE1 | P07998 | 1/20 | 0.37 |
| ▸ | DUT | P33316 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4170246 | 0.90 | HSP90AA1 (0.45) | HSP90AA1TYMPTYMSRNASE1DUT | |
| SCHEMBL3065199 | 0.83 | TK1 (0.47) | HSP90AA1 | |
| SCHEMBL3065197 | 0.83 | TK1 (0.47) | HSP90AA1 | |
| SCHEMBL5213020 | 0.81 | TYMP (0.43) | HSP90AA1TYMPTYMSRNASE1DUT | |
| SCHEMBL4176368 | 0.81 | TYMP (0.43) | HSP90AA1TYMPTYMSRNASE1DUT | |
| SCHEMBL3493524 | 0.80 | TYMP (0.54) | TYMPTYMS | |
| SCHEMBL13944237 | 0.80 | TK1 (0.42) | — | |
| SCHEMBL4169178 | 0.80 | TK1 (0.53) | — | |
| SCHEMBL13444847 | 0.79 | DUT (0.57) | HSP90AA1TYMPTYMSDUT | |
| SCHEMBL3571174 | 0.79 | DUT (0.57) | HSP90AA1TYMPTYMSDUT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090004137-A1 | Uridine Derivatives as Antiviral Drugs Against a Flaviviridae, Especially Hcv | INSTITUTE NATIONAL DE LA SAINTE ET DE LA RECHDERCHE MEDICALE (FR) | 2009-01-01 | — | — | US | disclosed |
| EP-1674104-A1 | Uridine derivatives as antiviral drugs against a flaviviridae, especially HCV | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2006-06-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090004137-A1 | Uridine Derivatives as Antiviral Drugs Against a Flaviviridae, Especially Hcv | NUDT1, UMPS, UPP1 | HSP90AA1 3549/4885TYMP 68/4885TYMS 274/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.