⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28845345 | 0.84 | POLB (0.39) | — | |
| SCHEMBL8865773 | 0.81 | — | — | |
| SCHEMBL21586125 | 0.81 | — | — | |
| SCHEMBL8249901 | 0.81 | — | — | |
| SCHEMBL16914162 | 0.75 | ENPP2 (0.37) | — | |
| SCHEMBL5779052 | 0.72 | TSHR (0.32) | — | |
| SCHEMBL1566271 | 0.72 | MAOB (0.30) | — | |
| SCHEMBL21513126 | 0.71 | FFAR4 (0.31) | — | |
| SCHEMBL10141715 | 0.71 | NQO1 (0.38) | — | |
| SCHEMBL11544480 | 0.70 | LTA4H (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106632027-A | Metal organic frame based on pyridine oxide ligand, and preparation method and application thereof | 山东师范大学 | 2017-05-10 | — | — | CN | claimed |
| CN-104447531-B | Preparation method of 3,5-dibromopyridine-N-oxide | 爱斯特（成都）生物制药有限公司 | 2017-03-22 | — | — | CN | claimed |
| CN-104447531-A | Preparation method of 3,5-dibromopyridine-N-oxide | ASTATECH CHENGDU PHARMACEUTICAL CO LTD | 2015-03-25 | — | — | CN | claimed |
| CN-112745261-A | Electron transport material, method for producing the same, electronic device, and display device | 广东聚华印刷显示技术有限公司 | 2021-05-04 | — | — | CN | disclosed |
| CN-106632027-A | Metal organic frame based on pyridine oxide ligand, and preparation method and application thereof | 山东师范大学 | 2017-05-10 | — | — | CN | disclosed |
| CN-104447531-B | Preparation method of 3,5-dibromopyridine-N-oxide | 爱斯特（成都）生物制药有限公司 | 2017-03-22 | — | — | CN | disclosed |
| CN-104447531-B | Preparation method of 3,5-dibromopyridine-N-oxide | 爱斯特（成都）生物制药有限公司 | 2017-03-22 | — | — | CN | disclosed |
| CN-104447531-B | Preparation method of 3,5-dibromopyridine-N-oxide | 爱斯特（成都）生物制药有限公司 | 2017-03-22 | — | — | CN | disclosed |
| CN-104080773-B | Nitrogen heterocyclic | 默克专利股份公司 | 2016-12-28 | — | — | CN | disclosed |
| US-9493444-B2 | Azaheterocyclic compounds | MERCK PATENT GMBH (DE) | 2016-11-15 | — | — | US | disclosed |
| EP-2807154-B1 | AZAHETEROCYCLIC COMPOUNDS | MERCK PATENT GMBH (DE) | 2015-12-23 | — | — | EP | disclosed |
| CN-1657523-A | Cyclic compounds | TANABE SEIYAKU CO (JP) | 2005-08-24 | — | — | CN | disclosed |
| US-20040142930-A1 | Cyclic compounds | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2004-07-22 | — | — | US | disclosed |
| US-20030229089-A1 | Cyclic compounds | TANABE SEIYAKU CO., LTD. (JP) | 2003-12-11 | — | — | US | disclosed |
| CN-1440393-A | cyclic compound | TANABE SEIYAKU CO (JP) | 2003-09-03 | — | — | CN | disclosed |
| EP-1277741-A1 | CYCLIC COMPOUNDS | TANABE SEIYAKU CO., LTD. (JP) | 2003-01-22 | — | — | EP | disclosed |
| EP-1047690-A1 | HETEROCYCLIC ETHER AND THIOETHER COMPOUNDS USEFUL IN CONTROLLING CHEMICAL SYNAPTIC TRANSMISSION | Abbott Laboratories (US) | 2000-11-02 | — | — | EP | disclosed |
| US-5948793-A | 3-pyridyloxymethyl heterocyclic ether compounds useful in controlling neurotransmitter release | ABBOTT LABORATORIES (US) | 1999-09-07 | — | — | US | disclosed |
| WO-1999032480-A1 | HETEROCYCLIC ETHER AND THIOETHER COMPOUNDS USEFUL IN CONTROLLING CHEMICAL SYNAPTIC TRANSMISSION | ABBOTT LABORATORIES (US) | 1999-07-01 | — | — | WO | disclosed |
| US-5914328-A | CONTROL DOPAMINE RELEASE, ACTIVATE CHOLINERGIC CHANNELS | ABBOTT LABORATORIES (US) | 1999-06-22 | — | — | US | disclosed |