SCHEMBL4175183

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4175190	1.00	NR1H3 (0.49)	NR1H3NFE2L2NR1H2TRPA1ALDH1A1
	SCHEMBL4165354	0.90	ALDH1A1 (0.46)	ALDH1A1TDP1L3MBTL1CYP1A1CYP1A2
	SCHEMBL4165347	0.90	ALDH1A1 (0.46)	ALDH1A1TDP1L3MBTL1CYP1A1CYP1A2
	SCHEMBL4172046	0.85	NR1H3 (0.55)	NR1H3NR1H2ALDH1A1TDP1L3MBTL1
	SCHEMBL4172051	0.85	NR1H3 (0.55)	NR1H3NR1H2ALDH1A1TDP1L3MBTL1
	SCHEMBL4179095	0.83	TDP1 (0.46)	NR1H3NR1H2ALDH1A1TDP1L3MBTL1
	SCHEMBL4179087	0.83	TDP1 (0.46)	NR1H3NR1H2ALDH1A1TDP1L3MBTL1
	SCHEMBL4161344	0.83	TDP1 (0.48)	NR1H3NR1H2TRPA1ALDH1A1TDP1
	SCHEMBL4161338	0.83	TDP1 (0.48)	NR1H3NR1H2TRPA1ALDH1A1TDP1
	SCHEMBL4175889	0.83	TDP1 (0.51)	NR1H3ALDH1A1TDP1L3MBTL1CYP1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.