SCHEMBL4172046

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4172051	1.00	NR1H3 (0.55)	NR1H3HTR1ANR1H2MEN1KMT2A
	SCHEMBL8801774	0.89	NR1H2 (0.62)	NR1H3HTR1ANR1H2MEN1KMT2A
	SCHEMBL4165347	0.86	ALDH1A1 (0.46)	HTR1AMEN1KMT2ALMNATDP1
	SCHEMBL4165354	0.86	ALDH1A1 (0.46)	HTR1AMEN1KMT2ALMNATDP1
	SCHEMBL4175183	0.85	NR1H3 (0.49)	NR1H3HTR1ANR1H2MEN1KMT2A
	SCHEMBL4175190	0.85	NR1H3 (0.49)	NR1H3HTR1ANR1H2MEN1KMT2A
	SCHEMBL4178238	0.83	TDP1 (0.50)	NR1H3HTR1AMEN1KMT2AMAPT
	SCHEMBL4178229	0.83	TDP1 (0.50)	NR1H3HTR1AMEN1KMT2AMAPT
	SCHEMBL4170153	0.83	ACHE (0.56)	MEN1KMT2AMAPTLMNATDP1
	SCHEMBL4171946	0.83	ACHE (0.56)	MEN1KMT2AMAPTLMNATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.