SCHEMBL4165347

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4165354	1.00	ALDH1A1 (0.46)	ALDH1A1TDP1L3MBTL1MAOBBCHE
	SCHEMBL4175183	0.90	NR1H3 (0.49)	ALDH1A1TDP1L3MBTL1MAOBBCHE
	SCHEMBL4175190	0.90	NR1H3 (0.49)	ALDH1A1TDP1L3MBTL1MAOBBCHE
	SCHEMBL4168874	0.89	CYP3A4 (0.48)	ALDH1A1TDP1L3MBTL1MAOBBCHE
	SCHEMBL4168884	0.89	CYP3A4 (0.48)	ALDH1A1TDP1L3MBTL1MAOBBCHE
	SCHEMBL4414342	0.89	ALDH1A1 (0.43)	ALDH1A1TDP1L3MBTL1MEN1CYP3A4
	SCHEMBL4414344	0.89	ALDH1A1 (0.43)	ALDH1A1TDP1L3MBTL1MEN1CYP3A4
	SCHEMBL4172046	0.86	NR1H3 (0.55)	ALDH1A1TDP1L3MBTL1MEN1HTR1A
	SCHEMBL4172051	0.86	NR1H3 (0.55)	ALDH1A1TDP1L3MBTL1MEN1HTR1A
	SCHEMBL4170167	0.83	L3MBTL1 (0.47)	TDP1L3MBTL1MAOBMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.