SCHEMBL4175575

SCHEMBL4175575

CC1CCCC(C)C1NC(=O)c1c(F)c(F)c(F)c(F)c1F

nearest known ligand 0.59

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TAS1R3 Q7RTX0 16/20 0.59
TAS1R1 Q7RTX1 15/20 0.59
TAS1R2 Q8TE23 15/20 0.59
CNR1 P21554 1/20 0.38
CNR2 P34972 1/20 0.38
HTT P42858 1/20 0.36
ALDH1A1 P00352 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4309782 0.81 TAS1R3 (0.66) TAS1R3TAS1R1TAS1R2
SCHEMBL4159220 0.81 TAS1R3 (0.66) TAS1R3TAS1R1TAS1R2
SCHEMBL4162795 0.81 TAS1R3 (0.66) TAS1R3TAS1R1TAS1R2
SCHEMBL31290293 0.77 TAS1R3 (0.73) TAS1R3TAS1R1TAS1R2HTT
SCHEMBL701897 0.74 TAS1R3 (1.00) TAS1R3TAS1R1TAS1R2ALDH1A1L3MBTL1
SCHEMBL702098 0.73 TAS1R3 (0.78) TAS1R3TAS1R1TAS1R2
SCHEMBL4159172 0.73 TAS1R3 (0.79) TAS1R3TAS1R1TAS1R2HTTALDH1A1
SCHEMBL4170527 0.73 TAS1R3 (0.62) TAS1R3TAS1R1TAS1R2
SCHEMBL4170336 0.72 TAS1R3 (0.67) TAS1R3TAS1R1TAS1R2HTT
SCHEMBL13927784 0.72 TAS1R3 (0.80) TAS1R3TAS1R1TAS1R2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090047379-A1 Benzamide Compounds Useful as High Potency Sweet Taste Enhancers DEWIS MARK L 2009-02-19 US disclosed
US-20090047379-A1 Benzamide Compounds Useful as High Potency Sweet Taste Enhancers DEWIS MARK L 2009-02-19 US disclosed
US-20090047379-A1 Benzamide Compounds Useful as High Potency Sweet Taste Enhancers DEWIS MARK L 2009-02-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090047379-A1 Benzamide Compounds Useful as High Potency Sweet Taste Enhancers TAS2R10, TAS2R50, TAS2R8 TAS1R3 27/4885TAS1R1 23/4885TAS1R2 11/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.