SCHEMBL4175937

SCHEMBL4175937

C=CC(O)(CCC)CCC

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
FDPS P14324 1/20 0.35
ALOX15 P16050 2/20 0.34
TSHR P16473 1/20 0.32
MEN1 O00255 1/20 0.30
CYP3A4 P08684 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10020726 0.89
SCHEMBL10900101 0.88 FDPS (0.39) FDPSTSHR
SCHEMBL8433925 0.83 TSHR (0.38) FDPSALOX15TSHRMEN1CYP3A4
SCHEMBL28803556 0.81 FDPS (0.41) FDPSTSHR
SCHEMBL31648195 0.79 FDPS (0.43) FDPSTSHR
SCHEMBL5152830 0.78 FDPS (0.32) FDPS
SCHEMBL5152833 0.78 FDPS (0.32) FDPS
SCHEMBL17422177 0.77
SCHEMBL4177702 0.75
SCHEMBL12837120 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112334454-B Environment-friendly olefin hydration reaction 佐治亚州立大学研究基金会公司 2024-04-30 CN disclosed
US-11708320-B2 Environmentally-friendly hydroazidation of olefins GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2023-07-25 US disclosed
US-11708320-B2 Environmentally-friendly hydroazidation of olefins GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2023-07-25 US disclosed
US-20210284601-A1 ENVIRONMENTALLY-FRIENDLY HYDROAZIDATION OF OLEFINS GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. 2021-09-16 US disclosed
CN-112334454-A Environmentally friendly olefin hydration reactions 佐治亚州立大学研究基金会公司 2021-02-05 CN disclosed
EP-3728633-A1 POLYMERASE CHAIN REACTION COMPOSITION COMPRISING AMINES THERMO FISHER SCIENTIFIC BALTICS UAB (LT) 2020-10-28 EP disclosed
US-10201545-B2 Styrenyl derivative compounds for treating ophthalmic diseases and disorders ACUCELA INC. (US) 2019-02-12 US disclosed
US-9421210-B2 Styrenyl derivative compounds for treating ophthalmic diseases and disorders ACUCELA INC. (US) 2016-08-23 US disclosed
US-9421210-B2 Styrenyl derivative compounds for treating ophthalmic diseases and disorders ACUCELA INC. (US) 2016-08-23 US disclosed
US-9421210-B2 Styrenyl derivative compounds for treating ophthalmic diseases and disorders ACUCELA INC. (US) 2016-08-23 US disclosed
US-20090170841-A1 Styrenyl Derivative Compounds for Treating Ophthalmic Diseases and Disorders ACUCELA INC. (US) 2009-07-02 US disclosed
WO-2008131368-A2 STYRENYL DERIVATIVE COMPOUNDS FOR TREATING OPHTHALMIC DISEASES AND DISORDERS ACUCELA INC. (US) 2008-10-30 WO disclosed
WO-2008131368-A2 STYRENYL DERIVATIVE COMPOUNDS FOR TREATING OPHTHALMIC DISEASES AND DISORDERS ACUCELA INC. (US) 2008-10-30 WO disclosed
US-5157087-A Organic peroxides and their use in the preparation of epoxide groups-containing (co)polymers AKZO N.V. (NL) 1992-10-20 US disclosed
EP-0273990-B1 NOVEL ORGANIC PEROXIDES AND THEIR USE IN THE PREPARATION OF EPOXIDE GROUPS CONTAINING (CO)POLYMERS AKZO N.V. (NL) 1991-09-18 EP disclosed
EP-0273990-A1 Novel organic peroxides and their use in the preparation of epoxide groups containing (co)polymers AKZO N.V. (NL) 1988-07-13 EP disclosed
US-4206140-A INSECTICIDES, ANTHELMINTICS ROUSSEL UCLAF (FR) 1980-06-03 US disclosed
US-4105697-A Process for the preparation of α, β-ethylenic aldehydes RHONE-POULENC INDUSTRIES (FR) 1978-08-08 US disclosed
US-4101574-A Cyclopropanecarboxylic acid chlorides ROUSSEL UCLAF (FR) 1978-07-18 US disclosed
US-3997586-A Cyclopropanecarboxylic acids and esters ROUSSEL-UCLAF (FR) 1976-12-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11708320-B2 Environmentally-friendly hydroazidation of olefins HAO2, AHR, HMOX1 FDPS 1474/4885ALOX15 22/4885TSHR 4317/4885
US-20210284601-A1 ENVIRONMENTALLY-FRIENDLY HYDROAZIDATION OF OLEFINS HAO2, AHR, HMOX1 FDPS 1474/4885ALOX15 22/4885TSHR 4317/4885
US-10201545-B2 Styrenyl derivative compounds for treating ophthalmic diseases and disorders ALDH1A2, STARD3, TXNRD2 FDPS 1936/4885ALOX15 711/4885TSHR 1547/4885
US-20090170841-A1 Styrenyl Derivative Compounds for Treating Ophthalmic Diseases and Disorders ALDH1A2, STARD3, TXNRD2 FDPS 1936/4885ALOX15 711/4885TSHR 1547/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.