Lysine

Lysine

SCHEMBL41760

Cl.NCCCCC(N)C(=O)O

nearest known ligand 0.95

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

PPARDPTGS1PTGS2dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Lysine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSR P00390 2/20 0.95
ARG2 P78540 4/20 0.61
ARG1 P05089 3/20 0.57
RNPEP Q9H4A4 1/20 0.56
NOS2 P35228 4/20 0.53
NOS1 P29475 3/20 0.53
BLM P54132 1/20 0.53
CYP1A2 P05177 3/20 0.50
NOS3 P29474 2/20 0.50
GGT1 P19440 2/20 0.50
TSHR P16473 2/20 0.50
CYP3A4 P08684 1/20 0.50
GRM8 O00222 1/20 0.50
GRM6 O15303 1/20 0.50
GRIN2D O15399 1/20 0.50
GRIN3B O60391 1/20 0.50
GRIK1 P39086 1/20 0.50
GRM5 P41594 1/20 0.50
GRIA1 P42261 1/20 0.50
GRIA2 P42262 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Lysine SCHEMBL875015 1.00 GSR (0.95) GSRARG2ARG1RNPEPNOS2
Lysine SCHEMBL706905 1.00 GSR (0.95) GSRARG2ARG1RNPEPNOS2
Lysine SCHEMBL16893975 1.00 GSR (0.95) GSRARG2ARG1RNPEPNOS2
Lysine SCHEMBL8029574 1.00 GSR (0.95) GSRARG2ARG1RNPEPNOS2
Lysine SCHEMBL41761 1.00 GSR (0.95) GSRARG2ARG1RNPEPNOS2
Lysine SCHEMBL1191963 1.00 GSR (0.95) GSRARG2ARG1RNPEPNOS2
Lysine SCHEMBL10582149 1.00 GSR (0.95) GSRARG2ARG1RNPEPNOS2
Lysine SCHEMBL9762590 1.00 GSR (0.95) GSRARG2ARG1RNPEPNOS2
Lysine SCHEMBL2478576 1.00 GSR (0.95) GSRARG2ARG1RNPEPNOS2
Lysine SCHEMBL30928253 1.00 GSR (0.95) GSRARG2ARG1RNPEPNOS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 13289 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026106819-A1 MICROCARRIERS WITH IMPROVED REHYDRATION CORNING INCORPORATED (US) 2026-05-21 WO claimed
CN-121674377-B Preparation method of human blood coagulation factor IX stock solution 深圳市卫光生物制品股份有限公司 2026-05-19 CN claimed
CN-122038067-A Solid beer flavor effervescent tablet and preparation method thereof 技源健康科技(江苏)有限公司 2026-05-15 CN claimed
CN-122004362-A Tryptophan-added bullfrog feed composition and application thereof 集美大学 2026-05-12 CN claimed
US-20260103511-A1 Liquid Pharmaceutical Formulations for an Anti-IL-1beta Antibody AVALO THERAPEUTICS INC (US) 2026-04-16 US claimed
US-20260060912-A1 SKIN CARE PRODUCT WITH PROTEIN MATRIX Eighth Day Labs, LLC (US) 2026-03-05 US claimed
US-20260007148-A1 TEXTURIZED FORMED PLANT PROTEIN PRODUCT AND METHOD FOR MANUFACTURING THE SAME BIOMUSH OY (FI) 2026-01-08 US claimed
EP-4674995-A1 TUNGSTEN POWDER MANUFACTURING METHOD, AND TUNGSTEN CARBIDE PRODUCT MANUFACTURING METHOD Kyocera Corporation (JP) 2026-01-07 EP claimed
EP-4666865-A2 CHEMICAL MITIGATION OF AFRICAN SWINE FEVER VIRUS AND CLASSICAL SWINE FEVER VIRUS Kansas State University Research Foundation (US) 2025-12-24 EP claimed
EP-4666864-A1 METHOD FOR PRODUCING MODIFIED PROTEIN-CONTAINING FOOD AJINOMOTO CO., INC. (JP) 2025-12-24 EP claimed
WO-1988006850-A1 SALT TASTE ENHANCER CENTER FOR INNOVATIVE TECHNOLOGY (US) 1988-09-22 WO claimed
EP-0280503-A2 Multivesicular liposomes having a biologically active substance encapsulated therein in the presence of a hydrochloride RESEARCH DEVELOPMENT FOUNDATION (US) 1988-08-31 EP claimed
US-4561911-A CONTAINING AMINO ACID NIPPON STEEL CORPORATION (JP) 1985-12-31 US claimed
EP-0076515-B1 RAPIDLY RELEASABLE MICROCAPSULES AND METHOD FOR THE PREPARATION THEREOF Tanabe Seiyaku Co., Ltd. (JP) 1985-07-03 EP claimed
EP-0140395-A1 Water soluble derivatives of 1-(2-hydroxyethyl)-2-methyl-5-nitro-imidazole having therapeutical activity, process for its preparation and related pharmaceutical compositions Pietro Isnardi & C. Spa (IT) 1985-05-08 EP claimed
EP-0076515-A1 Rapidly releasable microcapsules and method for the preparation thereof Tanabe Seiyaku Co., Ltd. (JP) 1983-04-13 EP claimed
US-4171381-A REDUCING SUGAR-AMINO ACID REACTION PRODUCT; SMEAR RESISTANT UNION CARBIDE CORPORATION (US) 1979-10-16 US claimed
US-4126628-A BASIC CATALYST CANADIAN PATENTS AND DEVELOPMENT LIMITED (CA) 1978-11-21 US claimed
US-4035513-A COSMETICS SHISEIDO CO., LTD. (JA) 1977-07-12 US claimed
US-3931308-A Process for conversion of lysine dihydrochloride to lysine monohydrochloride ALLIED CHEMICAL CORPORATION (US) 1976-01-06 US claimed