Known targets — ChEMBL curated mechanism
PPARDPTGS1PTGS2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Lysine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 2/20 | 0.95 |
| ▸ | ARG2 | P78540 | 4/20 | 0.61 |
| ▸ | ARG1 | P05089 | 3/20 | 0.57 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.56 |
| ▸ | NOS2 | P35228 | 4/20 | 0.53 |
| ▸ | NOS1 | P29475 | 3/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | NOS3 | P29474 | 2/20 | 0.50 |
| ▸ | GGT1 | P19440 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | GRM8 | O00222 | 1/20 | 0.50 |
| ▸ | GRM6 | O15303 | 1/20 | 0.50 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.50 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.50 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.50 |
| ▸ | GRM5 | P41594 | 1/20 | 0.50 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.50 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lysine SCHEMBL875015 | 1.00 | GSR (0.95) | GSRARG2ARG1RNPEPNOS2 | |
| Lysine SCHEMBL16893975 | 1.00 | GSR (0.95) | GSRARG2ARG1RNPEPNOS2 | |
| Lysine SCHEMBL8029574 | 1.00 | GSR (0.95) | GSRARG2ARG1RNPEPNOS2 | |
| Lysine SCHEMBL41761 | 1.00 | GSR (0.95) | GSRARG2ARG1RNPEPNOS2 | |
| Lysine SCHEMBL1191963 | 1.00 | GSR (0.95) | GSRARG2ARG1RNPEPNOS2 | |
| Lysine SCHEMBL10582149 | 1.00 | GSR (0.95) | GSRARG2ARG1RNPEPNOS2 | |
| Lysine SCHEMBL9762590 | 1.00 | GSR (0.95) | GSRARG2ARG1RNPEPNOS2 | |
| Lysine SCHEMBL41760 | 1.00 | GSR (0.95) | GSRARG2ARG1RNPEPNOS2 | |
| Lysine SCHEMBL2478576 | 1.00 | GSR (0.95) | GSRARG2ARG1RNPEPNOS2 | |
| Lysine SCHEMBL30928253 | 1.00 | GSR (0.95) | GSRARG2ARG1RNPEPNOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 486 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12178874-B2 | Aflibercept formulations containing a lysine salt as tonicifying agent and uses thereof | JUST-EVOTEC BIOLOGICS, INC. (US) | 2024-12-31 | — | — | US | claimed |
| CN-118914400-A | Method for accurately measuring content of chiral impurities of lysine hydrochloride by adopting high performance liquid chromatography | 江苏华泰晨光药业有限公司 | 2024-11-08 | — | — | CN | claimed |
| CN-116926523-A | Electroless copper plating regulator and preparation method and application thereof | 上海天承化学有限公司 | 2023-10-24 | — | — | CN | claimed |
| CN-114656960-A | Lysine-based carbon quantum dot corrosion inhibitor and preparation method and application thereof | 江西理工大学 | 2022-06-24 | — | — | CN | claimed |
| CN-113150064-A | Artificial synthesis method and application of antibacterial and insect-resistant peptide | 中山大学 | 2021-07-23 | — | — | CN | claimed |
| US-20170252274-A1 | POLYUREA CAPSULES PREPARED WITH ALIPHATIC ISOCYANATES AND AMINES | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2017-09-07 | — | — | US | claimed |
| CN-103204783-B | A kind of preparation method of D-lysine hydrochloride | HUACHANG PHARMACEUTICAL CO., LTD., ZHANGJIAGANG CITY (CN) | 2015-09-02 | — | — | CN | claimed |
| US-20130337023-A1 | POLYUREA CAPSULES PREPARED WITH ALIPHATIC ISOCYANATES AND AMINES | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2013-12-19 | — | — | US | claimed |
| CN-103204783-A | Preparation method of D-lysine hydrochloride | ZHANGJIAGANG HUACHANG PHARMACEUTICAL CO LTD | 2013-07-17 | — | — | CN | claimed |
| CN-102766060-A | Preparation method of D-lysine hydrochloride | CHENGDU BAISHIXING SCIENCE AND TECHNOLOGY INDUSTRY CO LTD | 2012-11-07 | — | — | CN | claimed |
| CN-102392061-A | Chemical-enzyme method for preparing D-basic amino acid hydrochloride | UNIV CHONGQING POSTS & TELECOM | 2012-03-28 | — | — | CN | claimed |
| EP-2258183-A1 | Compounds and uses for the treatment of airway diseases and for the delivery of airway drugs | The University of North Carolina at Chapel Hill (US) | 2010-12-08 | — | — | EP | claimed |
| EP-1139746-A4 | COMPOUNDS AND METHODS FOR THE TREATMENT OF AIRWAY DISEASES AND FOR THE DELIVERY OF AIRWAY DRUGS | UNIV NORTH CAROLINA (US) | 2003-09-17 | — | — | EP | claimed |
| JP-2002532520-A | — | — | 2002-10-02 | — | — | JP | claimed |
| US-20020099023-A1 | Compounds and methods for the treatment of airway diseases and for the delivery of airway drugs | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2002-07-25 | — | — | US | claimed |
| EP-1139746-A1 | COMPOUNDS AND METHODS FOR THE TREATMENT OF AIRWAY DISEASES AND FOR THE DELIVERY OF AIRWAY DRUGS | The University of North Carolina at Chapel Hill (US) | 2001-10-10 | — | — | EP | claimed |
| WO-2000036915-A1 | COMPOUNDS AND METHODS FOR THE TREATMENT OF AIRWAY DISEASES AND FOR THE DELIVERY OF AIRWAY DRUGS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2000-06-29 | — | — | WO | claimed |
| US-4390722-A | CRYSTALLIZATION FROM SUPERSATURATED SOLUTION USING AMINO ACID AS AS CRYSTAL INHIBITOR | YEDA RESEARCH AND DEVELOPMENT COMPANY LTD. (IL) | 1983-06-28 | — | — | US | claimed |
| US-4035513-A | COSMETICS | SHISEIDO CO., LTD. (JA) | 1977-07-12 | — | — | US | claimed |
| US-12558297-B2 | Consumer product with controlled release, biodegradable core-shell microcapsule compositions | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2026-02-24 | — | — | US | disclosed |
| US-20260028770-A1 | SURFACE MODIFIED MICROCAPSULES | INT FLAVORS & FRAGRANCES INC (US) | 2026-01-29 | — | — | US | disclosed |
| EP-3611247-B2 | FABRIC TREATMENT COMPOSITIONS COMPRISING BENEFIT AGENT CAPSULES | PROCTER & GAMBLE (US) | 2026-01-07 | — | — | EP | disclosed |
| US-12514794-B2 | Microcapsules prepared from proteins | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2026-01-06 | — | — | US | disclosed |
| WO-2025265075-A1 | METHODS OF CLEARING MUCUS FROM THE LUNGS | PARION SCIENCES, INC. (US) | 2025-12-26 | — | — | WO | disclosed |
| EP-3784707-B1 | STABLE POLYUREA MICROCAPSULE COMPOSITIONS | INT FLAVORS & FRAGRANCES INC (US) | 2025-12-24 | — | — | EP | disclosed |
| EP-4667651-A2 | STABLE POLYUREA MICROCAPSULE COMPOSITIONS | International Flavors and Fragrances Inc. (US) | 2025-12-24 | — | — | EP | disclosed |
| US-12454791-B2 | Surface modified microcapsules | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2025-10-28 | — | — | US | disclosed |
| CN-120775937-A | Method for preparing D-lysine hydrochloride through enzyme-catalyzed cascade reaction | 上海瀚鸿科技股份有限公司 | 2025-10-14 | — | — | CN | disclosed |
| CN-120775937-A | Method for preparing D-lysine hydrochloride through enzyme-catalyzed cascade reaction | 上海瀚鸿科技股份有限公司 | 2025-10-14 | — | — | CN | disclosed |
| US-20250302760-A1 | BIODEGRADABLE, CONTROLLED RELEASE MICROCAPSULES | ENCAPSYS, LLC (US) | 2025-10-02 | — | — | US | disclosed |
| US-12419815-B2 | Microcapsule compositions stabilized with viscosity control agents | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2025-09-23 | — | — | US | disclosed |
| US-12409113-B2 | Polyurea or polyurethane capsules | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2025-09-09 | — | — | US | disclosed |
| US-12409431-B2 | Guar gum microcapsules | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2025-09-09 | — | — | US | disclosed |
| US-12390783-B2 | Protein microcapsules and method of preparing the same | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2025-08-19 | — | — | US | disclosed |
| US-12378129-B2 | Layered silicate partially modified with amino acid | BYK-CHEMIE GMBH (DE) | 2025-08-05 | — | — | US | disclosed |
| EP-4370469-B1 | LAYERED SILICATE PARTIALLY MODIFIED WITH AMINO ACID | BYK CHEMIE GMBH (DE) | 2025-07-23 | — | — | EP | disclosed |
| US-12357547-B2 | Compositions containing microcapsules | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2025-07-15 | — | — | US | disclosed |
| US-12303855-B2 | Stable polyurea microcapsule compositions for aldehyde fragrances | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2025-05-20 | — | — | US | disclosed |
| US-12303856-B2 | Hydroxyethyl cellulose microcapsules | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2025-05-20 | — | — | US | disclosed |
| US-12274771-B2 | Polyurea capsule compositions | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2025-04-15 | — | — | US | disclosed |
| US-20250115561-A1 | BIPHENYL-SUBSTITUTED EPITHELIAL SODIUM CHANNEL BLOCKING COMPOUNDS | PARION SCIENCES, INC. (US) | 2025-04-10 | — | — | US | disclosed |
| US-12269002-B2 | Microcapsule compositions | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2025-04-08 | — | — | US | disclosed |
| US-20250109110-A1 | BICYCLIC-SUBSTITUTED EPITHELIAL SODIUM CHANNEL BLOCKING COMPOUNDS | PARION SCIENCES, INC. (US) | 2025-04-03 | — | — | US | disclosed |
| CN-119325465-A | Biphenyl substituted epithelial sodium channel blocking compounds | 帕里昂科学公司 | 2025-01-17 | — | — | CN | disclosed |
| CN-119306663-A | Continuous production method and system for lactam monomer | 中国石油化工股份有限公司 | 2025-01-14 | — | — | CN | disclosed |
| US-20250000761-A1 | BIODEGRADABLE MICROCAPSULES | INT FLAVORS & FRAGRANCES INC (US) | 2025-01-02 | — | — | US | disclosed |
| US-12178874-B2 | Aflibercept formulations containing a lysine salt as tonicifying agent and uses thereof | JUST-EVOTEC BIOLOGICS, INC. (US) | 2024-12-31 | — | — | US | disclosed |
| CN-113453653-B | Microcapsule composition prepared from polysaccharide | 国际香料和香精公司 | 2024-11-29 | — | — | CN | disclosed |
| CN-118914400-A | Method for accurately measuring content of chiral impurities of lysine hydrochloride by adopting high performance liquid chromatography | 江苏华泰晨光药业有限公司 | 2024-11-08 | — | — | CN | disclosed |
| CN-118914400-A | Method for accurately measuring content of chiral impurities of lysine hydrochloride by adopting high performance liquid chromatography | 江苏华泰晨光药业有限公司 | 2024-11-08 | — | — | CN | disclosed |
| US-20240368502-A1 | BIODEGRADABLE MICROCAPSULES | INT FLAVORS & FRAGRANCES INC (US) | 2024-11-07 | — | — | US | disclosed |
| CN-118812432-A | Continuous production method and system of lactam monomer | 中国石油化工股份有限公司 | 2024-10-22 | — | — | CN | disclosed |
| CN-118807655-A | Method and reaction system for continuously producing lactam monomer | 中国石油化工股份有限公司 | 2024-10-22 | — | — | CN | disclosed |
| EP-4438132-A2 | STABLE MICROCAPSULE COMPOSITIONS | International Flavors & Fragrances Inc. (US) | 2024-10-02 | — | — | EP | disclosed |
| EP-3478249-B1 | STABLE MICROCAPSULE COMPOSITIONS | INT FLAVORS & FRAGRANCES INC (US) | 2024-09-11 | — | — | EP | disclosed |
| WO-2024180569-A1 | A SYNERGISTIC AQUEOUS NEBULIZATION SUSPENSION FOR MANAGEMENT OF INFECTIOUS RESPIRATORY DISORDERS AND PROCESS OF PREPARATION | KANDURI AJAYKUMAR BALRAJ (IN) | 2024-09-06 | — | — | WO | disclosed |
| EP-4425181-A1 | COMPOSITION FOR DETECTING OR MEASURING ANALYTE | Bertis Inc (KR) | 2024-09-04 | — | — | EP | disclosed |
| CN-115089512-B | Polyurea capsule composition | 国际香料和香精公司 | 2024-08-27 | — | — | CN | disclosed |
| EP-3416610-B1 | MICROCAPSULE COMPOSITION | INT FLAVORS & FRAGRANCES INC (US) | 2024-08-14 | — | — | EP | disclosed |
| CN-113950315-B | Consumer product with controlled release biodegradable core-shell microcapsule composition | 国际香料和香精公司 | 2024-08-02 | — | — | CN | disclosed |
| EP-4405092-A1 | BIODEGRADABLE MICROCAPSULES | International Flavors & Fragrances Inc. (US) | 2024-07-31 | — | — | EP | disclosed |
| US-12048755-B2 | Microcapsule compositions prepared from polysaccharides | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2024-07-30 | — | — | US | disclosed |
| CN-113993499-B | Sustainable core-shell microcapsules prepared with a combination of cross-linking agents | 国际香料和香精公司 | 2024-07-23 | — | — | CN | disclosed |
| US-20240217829-A1 | LAYERED SILICATE PARTIALLY MODIFIED WITH AMINO ACID | BYK-CHEMIE GMBH (DE) | 2024-07-04 | — | — | US | disclosed |
| US-20240199998-A1 | FABRIC TREATMENT COMPOSITIONS COMPRISING BENEFIT AGENT CAPSULES | PROCTER & GAMBLE (US) | 2024-06-20 | — | — | US | disclosed |
| US-20240199992-A1 | FABRIC TREATMENT COMPOSITIONS COMPRISING BENEFIT AGENT CAPSULES | PROCTER & GAMBLE (US) | 2024-06-20 | — | — | US | disclosed |
| US-12013574-B2 | Stable microcapsule compositions | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2024-06-18 | — | — | US | disclosed |
| CN-118201703-A | Biodegradable microcapsules | 国际香料和香精公司 | 2024-06-14 | — | — | CN | disclosed |
| EP-4376997-A1 | BIODEGRADABLE MICROCAPSULES | International Flavors & Fragrances Inc. (US) | 2024-06-05 | — | — | EP | disclosed |
| EP-4370469-A1 | LAYERED SILICATE PARTIALLY MODIFIED WITH AMINO ACID | BYK-Chemie GmbH (DE) | 2024-05-22 | — | — | EP | disclosed |
| CN-117881473-A | Biodegradable microcapsules | 国际香料和香精公司 | 2024-04-12 | — | — | CN | disclosed |
| US-11952492-B2 | Biodegradable, controlled release microcapsules | ENCAPSYS, LLC (US) | 2024-04-09 | — | — | US | disclosed |
| US-11952560-B2 | Fabric treatment compositions comprising benefit agent capsules | THE PROCTER & GAMBLE COMPANY (US) | 2024-04-09 | — | — | US | disclosed |
| US-11952555-B2 | Fabric treatment compositions comprising benefit agent capsules | THE PROCTER & GAMBLE COMPANY (US) | 2024-04-09 | — | — | US | disclosed |
| CN-117615995-A | Layered silicate modified with amino acid moieties | 毕克化学有限公司 | 2024-02-27 | — | — | CN | disclosed |
| EP-3897955-B1 | HYDROXYETHYL CELLULOSE MICROCAPSULES | INT FLAVORS & FRAGRANCES INC (US) | 2024-02-07 | — | — | EP | disclosed |
| CN-113453654-B | Microcapsule composition | 国际香料和香精公司 | 2024-02-02 | — | — | CN | disclosed |
| US-20240004145-A1 | Stable Microcapsule Compositions | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2024-01-04 | — | — | US | disclosed |
| CN-116926523-A | Electroless copper plating regulator and preparation method and application thereof | 上海天承化学有限公司 | 2023-10-24 | — | — | CN | disclosed |
| EP-4247537-A1 | BIODEGRADABLE, CONTROLLED RELEASE MICROCAPSULES | Encapsys, LLC (US) | 2023-09-27 | — | — | EP | disclosed |
| CN-116764558-A | Microcapsule compositions stabilized with viscosity control agents | 国际香料和香精公司 | 2023-09-19 | — | — | CN | disclosed |
| CN-113939192-B | Controlled release biodegradable core-shell microcapsule compositions | 国际香料和香精公司 | 2023-08-11 | — | — | CN | disclosed |
| CN-116472103-A | Biodegradable controlled release microcapsules | 恩盖普有限公司 | 2023-07-21 | — | — | CN | disclosed |
| CN-112423875-B | Surface-modified microcapsules | 国际香料和香精公司 | 2023-07-21 | — | — | CN | disclosed |
| US-20230220311-A1 | FABRIC TREATMENT COMPOSITIONS COMPRISING BENEFIT AGENT CAPSULES | PROCTER & GAMBLE (US) | 2023-07-13 | — | — | US | disclosed |
| EP-3033066-B1 | POLYUREA OR POLYURETHANE CAPSULES | INT FLAVORS & FRAGRANCES INC (US) | 2023-07-12 | — | — | EP | disclosed |
| EP-4209264-A1 | MICROCAPSULE COMPOSITIONS STABILIZED WITH VISCOSITY CONTROL AGENTS | International Flavors & Fragrances Inc. (US) | 2023-07-12 | — | — | EP | disclosed |
| CN-112041361-B | Stabilized polyurea microcapsule compositions | 国际香料和香精公司 | 2023-06-30 | — | — | CN | disclosed |
| CN-113453794-B | Hydroxyethyl cellulose microcapsules | 国际香料和香精公司 | 2023-06-27 | — | — | CN | disclosed |
| CN-109689197-B | Microcapsule compositions stabilized with viscosity control agents | 国际香料和香精公司 | 2023-06-23 | — | — | CN | disclosed |
| US-20230172820-A1 | Compositions Containing Microcapsules | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2023-06-08 | — | — | US | disclosed |
| CN-114656960-B | Lysine-based carbon quantum dot corrosion inhibitor and preparation method and application thereof | 江西理工大学 | 2023-05-19 | — | — | CN | disclosed |
| WO-2023075435-A1 | COMPOSITION FOR DETECTING OR MEASURING ANALYTE | 주식회사 베르티스 | 2023-05-04 | — | — | WO | disclosed |
| EP-3512625-B1 | MICROCAPSULE COMPOSITIONS STABILIZED WITH VISCOSITY CONTROL AGENTS | INT FLAVORS & FRAGRANCES INC (US) | 2023-04-26 | — | — | EP | disclosed |
| US-11634668-B2 | Fabric treatment compositions comprising benefit agent capsules | THE PROCTER & GAMBLE COMPANY (US) | 2023-04-25 | — | — | US | disclosed |
| CN-113150064-B | Artificial synthesis method and application of antibacterial and insect-resistant peptide | 中山大学 | 2023-04-11 | — | — | CN | disclosed |
| CN-113150064-B | Artificial synthesis method and application of antibacterial and insect-resistant peptide | 中山大学 | 2023-04-11 | — | — | CN | disclosed |
| WO-2023049260-A1 | BIODEGRADABLE MICROCAPSULES | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2023-03-30 | — | — | WO | disclosed |
| EP-4154974-A1 | BIODEGRADABLE MICROCAPSULES | International Flavors & Fragrances Inc. (US) | 2023-03-29 | — | — | EP | disclosed |
| US-11602494-B2 | Compositions containing microcapsules coated with deposition proteins | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2023-03-14 | — | — | US | disclosed |
| US-20230046103-A1 | Stable Microcapsule Compositions | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2023-02-16 | — | — | US | disclosed |
| US-20230051314-A1 | BIODEGRADABLE MICROCAPSULES | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2023-02-16 | — | — | US | disclosed |
| US-11578042-B2 | 3,5-diamino-6-chloro-N-(N-(4-(4-(2-(hexyl(2,3,4,5,6-pentahydroxyhexyl)amino)ethoxy)phenyl)butyl)carbamimidoyl)pyrazine-2-carboxamide | PARION SCIENCES, INC. (US) | 2023-02-14 | — | — | US | disclosed |
| WO-2023009514-A1 | BIODEGRADABLE MICROCAPSULES | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2023-02-02 | — | — | WO | disclosed |
| EP-4124383-A1 | BIODEGRADABLE MICROCAPSULES | International Flavors & Fragrances Inc. (US) | 2023-02-01 | — | — | EP | disclosed |
| WO-2023285308-A1 | LAYERED SILICATE PARTIALLY MODIFIED WITH AMINO ACID | BYK-CHEMIE GMBH (DE) | 2023-01-19 | — | — | WO | disclosed |
| US-11540985-B2 | Stable microcapsule compositions | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2023-01-03 | — | — | US | disclosed |
| US-11491089-B2 | Reloadable microcapsules | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2022-11-08 | — | — | US | disclosed |
| CN-115089512-A | Polyurea capsule composition | 国际香料和香精公司 | 2022-09-23 | — | — | CN | disclosed |
| US-20220283131-A1 | COMPOSITION FOR DETECTING OR MEASURING ANALYTES | BERTIS CO., LTD. (KR) | 2022-09-08 | — | — | US | disclosed |
| US-20220250025-A1 | PROTEIN MICROCAPSULES AND METHOD OF PREPARING THE SAME | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2022-08-11 | — | — | US | disclosed |
| US-20220226797-A1 | SUSTAINABLE CORE-SHELL MICROCAPSULES PREPARED WITH COMBINATIONS OF CROSS-LINKERS | INT FLAVORS & FRAGRANCES INC (US) | 2022-07-21 | — | — | US | disclosed |
| CN-114656960-A | Lysine-based carbon quantum dot corrosion inhibitor and preparation method and application thereof | 江西理工大学 | 2022-06-24 | — | — | CN | disclosed |
| US-20220195342-A1 | FABRIC TREATMENT COMPOSITIONS COMPRISING BENEFIT AGENT CAPSULES | PROCTER & GAMBLE (US) | 2022-06-23 | — | — | US | disclosed |
| CN-108697591-B | Polyurea capsule composition | 国际香料和香精公司 | 2022-06-17 | — | — | CN | disclosed |
| US-20220175636-A1 | CONSUMER PRODUCT WITH CONTROLLED RELEASE, BIODEGRADABLE CORE-SHELL MICROCAPSULE COMPOSITIONS | INT FLAVORS & FRAGRANCES INC (US) | 2022-06-09 | — | — | US | disclosed |
| US-20220177815-A1 | CONTROLLED RELEASE, BIODEGRADABLE CORE-SHELL MICROCAPSULE COMPOSITIONS | INT FLAVORS & FRAGRANCES INC (US) | 2022-06-09 | — | — | US | disclosed |
| WO-2022109163-A1 | BIODEGRADABLE, CONTROLLED RELEASE MICROCAPSULES | ENCAPSYS, LLC (US) | 2022-05-27 | — | — | WO | disclosed |
| US-20220162444-A1 | BIODEGRADABLE, CONTROLLED RELEASE MICROCAPSULES | ENCAPSYS, LLC (US) | 2022-05-26 | — | — | US | disclosed |
| US-11339356-B2 | Liquid fabric treatment compositions comprising brightener | THE PROCTER & GAMBLE COMPANY (US) | 2022-05-24 | — | — | US | disclosed |
| CN-112513239-B | Fabric treatment composition comprising benefit agent capsules | 宝洁公司 | 2022-05-10 | — | — | CN | disclosed |
| CN-112534033-B | Fabric treatment composition comprising benefit agent capsules | 宝洁公司 | 2022-04-29 | — | — | CN | disclosed |
| US-11312924-B2 | Fabric treatment compositions comprising benefit agent capsules | THE PROCTER & GAMBLE COMPANY (US) | 2022-04-26 | — | — | US | disclosed |
| CN-114369505-A | Fabric treatment composition comprising benefit agent capsules | 宝洁公司 | 2022-04-19 | — | — | CN | disclosed |
| CN-112567012-B | Liquid fabric treatment composition comprising a whitening agent | 宝洁公司 | 2022-03-29 | — | — | CN | disclosed |
| US-20220071864-A1 | HYDROXYETHYL CELLULOSE MICROCAPSULES | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2022-03-10 | — | — | US | disclosed |
| US-20220071862-A1 | MICROCAPSULE COMPOSITIONS | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2022-03-10 | — | — | US | disclosed |
| WO-2022050529-A1 | COMPOSITION FOR DETECTING OR MEASURING ANALYTE | ㈜베르티스 | 2022-03-10 | — | — | WO | disclosed |
| US-20220071865-A1 | MICROCAPSULES PREPARED FROM PROTEINS | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2022-03-10 | — | — | US | disclosed |
| EP-3952823-A1 | CONSUMER PRODUCT WITH CONTROLLED RELEASE, BIODEGRADABLE CORE-SHELL MICROCAPSULE COMPOSITIONS | International Flavors & Fragrances Inc. (US) | 2022-02-16 | — | — | EP | disclosed |
| EP-3952648-A1 | CONTROLLED RELEASE, BIODEGRADABLE CORE-SHELL MICROCAPSULE COMPOSITIONS | International Flavors & Fragrances Inc. (US) | 2022-02-16 | — | — | EP | disclosed |
| EP-3952824-A1 | SUSTAINABLE CORE-SHELL MICROCAPSULES PREPARED WITH COMBINATIONS OF CROSS-LINKERS | International Flavors & Fragrances Inc. (US) | 2022-02-16 | — | — | EP | disclosed |
| US-20220040658-A1 | GUAR GUM MICROCAPSULES | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2022-02-10 | — | — | US | disclosed |
| CN-113993499-A | Sustainable core-shell microcapsules prepared with a combination of cross-linkers | 国际香料和香精公司 | 2022-01-28 | — | — | CN | disclosed |
| CN-113950315-A | Consumer products with controlled release biodegradable core-shell microcapsule compositions | 国际香料和香精公司 | 2022-01-18 | — | — | CN | disclosed |
| CN-113939192-A | Controlled release biodegradable core-shell microcapsule compositions | 国际香料和香精公司 | 2022-01-14 | — | — | CN | disclosed |
| US-20220008886-A1 | BIODEGRADABLE MICROCAPSULES | INT FLAVORS & FRAGRANCES INC (US) | 2022-01-13 | — | — | US | disclosed |
| US-20220008299-A1 | Compositions Containing Microcapsules Coated with Deposition Proteins | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2022-01-13 | — | — | US | disclosed |
| EP-3425036-B1 | BRANCHED POLYETHYLENEIMINE MICROCAPSULES | INT FLAVORS & FRAGRANCES INC (US) | 2022-01-05 | — | — | EP | disclosed |
| EP-3897522-A1 | MICROCAPSULE COMPOSITIONS | International Flavors & Fragrances Inc. (US) | 2021-10-27 | — | — | EP | disclosed |
| EP-3897525-A1 | MICROCAPSULE COMPOSITIONS PREPARED FROM POLYSACCHARIDES | International Flavors & Fragrances Inc. (US) | 2021-10-27 | — | — | EP | disclosed |
| EP-3897955-A1 | HYDROXYETHYL CELLULOSE MICROCAPSULES | International Flavors & Fragrances Inc. (US) | 2021-10-27 | — | — | EP | disclosed |
| EP-3897524-A2 | PROTEIN MICROCAPSULES AND METHOD OF PREPARING THE SAME | International Flavors & Fragrances Inc. (US) | 2021-10-27 | — | — | EP | disclosed |
| EP-3897523-A2 | MICROCAPSULES PREPARED FROM PROTEINS | International Flavors & Fragrances Inc. (US) | 2021-10-27 | — | — | EP | disclosed |
| EP-3897521-A1 | GUAR GUM MICROCAPSULES | International Flavors & Fragrances Inc. (US) | 2021-10-27 | — | — | EP | disclosed |
| US-11129778-B2 | Compositions containing microcapsules coated with deposition proteins | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2021-09-28 | — | — | US | disclosed |
| CN-113453653-A | Microcapsule composition prepared from polysaccharide | 国际香料和香精公司 | 2021-09-28 | — | — | CN | disclosed |
| CN-113453654-A | Microcapsule composition | 国际香料和香精公司 | 2021-09-28 | — | — | CN | disclosed |
| CN-113453794-A | Hydroxyethyl cellulose microcapsules | 国际香料和香精公司 | 2021-09-28 | — | — | CN | disclosed |
| CN-113453655-A | Guar gum microcapsule | 国际香料和香精公司 | 2021-09-28 | — | — | CN | disclosed |
| CN-113453656-A | Microcapsules prepared from proteins | 国际香料和香精公司 | 2021-09-28 | — | — | CN | disclosed |
| CN-113438939-A | Protein microcapsule and preparation method thereof | 国际香料和香精公司 | 2021-09-24 | — | — | CN | disclosed |
| US-20210237021-A1 | STABLE POLYUREA MICROCAPSULE COMPOSITIONS | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2021-08-05 | — | — | US | disclosed |
| CN-113150064-A | Artificial synthesis method and application of antibacterial and insect-resistant peptide | 中山大学 | 2021-07-23 | — | — | CN | disclosed |
| CN-113150064-A | Artificial synthesis method and application of antibacterial and insect-resistant peptide | 中山大学 | 2021-07-23 | — | — | CN | disclosed |
| CN-108033921-B | 3, 5-diamino-6-chloro-N- (N- (4- (4- (2- (hexyl (2,3,4,5, 6-pentahydroxyhexyl) amino) ethoxy) phenyl) butyl) carbamimidoyl) pyrazine-2-carboxamide | 帕里昂科学公司 | 2021-07-20 | — | — | CN | disclosed |
| EP-3848444-A1 | LIQUID FABRIC TREATMENT COMPOSITIONS COMPRISING BRIGHTENER | The Procter & Gamble Company (US) | 2021-07-14 | — | — | EP | disclosed |
| EP-3848442-A1 | FABRIC TREATMENT COMPOSITIONS COMPRISING BENEFIT AGENT CAPSULES | The Procter & Gamble Company (US) | 2021-07-14 | — | — | EP | disclosed |
| EP-3848443-A1 | FABRIC TREATMENT COMPOSITIONS COMPRISING BENEFIT AGENT CAPSULES | The Procter & Gamble Company (US) | 2021-07-14 | — | — | EP | disclosed |
| US-20210207317-A1 | SURFACE MODIFIED MICROCAPSULES | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2021-07-08 | — | — | US | disclosed |
| US-20210170029-A1 | AFLIBERCEPT FORMULATIONS CONTAINING A LYSINE SALT AS TONICIFYING AGENT AND USES THEREOF | Just-Evotec Biologies, Inc. (US) | 2021-06-10 | — | — | US | disclosed |
| EP-3801869-A1 | SURFACE MODIFIED MICROCAPSULES | International Flavors & Fragrances Inc. (US) | 2021-04-14 | — | — | EP | disclosed |
| US-10968233-B2 | Monothiol mucolytic agents | PARION SCIENCES, INC. (US) | 2021-04-06 | — | — | US | disclosed |
| CN-112567012-A | Liquid fabric treatment composition comprising a whitening agent | 宝洁公司 | 2021-03-26 | — | — | CN | disclosed |
| CN-112534033-A | Fabric treatment composition comprising benefit agent capsules | 宝洁公司 | 2021-03-19 | — | — | CN | disclosed |
| CN-112513239-A | Fabric treatment composition comprising benefit agent capsules | 宝洁公司 | 2021-03-16 | — | — | CN | disclosed |
| EP-3611247-B1 | FABRIC TREATMENT COMPOSITIONS COMPRISING BENEFIT AGENT CAPSULES | PROCTER & GAMBLE (US) | 2021-03-10 | — | — | EP | disclosed |
| EP-3611246-B1 | FABRIC TREATMENT COMPOSITIONS COMPRISING BENEFIT AGENT CAPSULES | PROCTER & GAMBLE (US) | 2021-03-10 | — | — | EP | disclosed |
| EP-3611245-B1 | LIQUID FABRIC TREATMENT COMPOSITIONS COMPRISING BRIGHTENER | PROCTER & GAMBLE (US) | 2021-03-10 | — | — | EP | disclosed |
| EP-3784707-A1 | STABLE POLYUREA MICROCAPSULE COMPOSITIONS | International Flavors & Fragrances Inc. (US) | 2021-03-03 | — | — | EP | disclosed |
| CN-112423875-A | Surface modified microcapsules | 国际香料和香精公司 | 2021-02-26 | — | — | CN | disclosed |
| CN-112321472-A | Novel monothiol mucolytic agents | 帕里昂科学公司 | 2021-02-05 | — | — | CN | disclosed |
| US-20210024471-A1 | 3,5-DIAMINO-6-CHLORO-N-(N-(4-(4-(2-(HEXYL(2,3,4,5,6-PENTAHYDROXYHEXYL)AMINO)ETHOXY)PHENYL)BUTYL)CARBAMIMIDOYL)PYRAZINE-2-CARBOXAMIDE | PARION SCIENCES, INC. (US) | 2021-01-28 | — | — | US | disclosed |
| CN-112041361-A | Stabilized polyurea microcapsule compositions | 国际香料和香精公司 | 2020-12-04 | — | — | CN | disclosed |
| US-20200360244-A1 | POLYUREA CAPSULES PREPARED WITH ALIPHATICISOCYANATES AND AMINES | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2020-11-19 | — | — | US | disclosed |
| WO-2020209908-A1 | CONSUMER PRODUCT WITH CONTROLLED RELEASE, BIODEGRADABLE CORE-SHELL MICROCAPSULE COMPOSITIONS | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2020-10-15 | — | — | WO | disclosed |
| WO-2020209907-A1 | CONTROLLED RELEASE, BIODEGRADABLE CORE-SHELL MICROCAPSULE COMPOSITIONS | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2020-10-15 | — | — | WO | disclosed |
| WO-2020209909-A1 | SUSTAINABLE CORE-SHELL MICROCAPSULES PREPARED WITH COMBINATIONS OF CROSS-LINKERS | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2020-10-15 | — | — | WO | disclosed |
| EP-3713591-A1 | AFLIBERCEPT FORMULATIONS CONTAINING A LYSINE SALT AS TONICIFYING AGENT AND USES THEREOF | Just-Evotec Biologics, Inc. (US) | 2020-09-30 | — | — | EP | disclosed |
| CN-107614480-B | Novel monothiol mucolytic agents | 帕里昂科学公司 | 2020-09-15 | — | — | CN | disclosed |
| US-20200281826-A1 | COMPOSITIONS CONTAINING MICROCAPSULES COATED WITH DEPOSITION PROTEINS | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2020-09-10 | — | — | US | disclosed |
| US-10752597-B2 | 3,5-diamino-6-chloro-N—(N-(4-(4-(2-(hexyl(2,3,4,5,6-pentahydroxyhexyl)amino)ethoxy)phenyl)butyl)carbamimidoyl)pyrazine-2-carboxamide | PARION SCIENCES, INC. (US) | 2020-08-25 | — | — | US | disclosed |
| EP-3693361-A1 | 3,5-DIAMINO-6-CHLORO-N-(N-(4-(4-(2-(HEXYL(2,3,4,5,6-PENTA-HYDROXYHEXYL)AMINO)ETHOXY)PHENYL)BUTYL) CARBAMIMIDOYL)PYRAZINE-2-CARBOXAMIDE | Parion Sciences, Inc. (US) | 2020-08-12 | — | — | EP | disclosed |
| EP-2841138-B1 | AEROSOL DELIVERY SYSTEMS | PARION SCIENCES INC (US) | 2020-07-01 | — | — | EP | disclosed |
| CN-111356471-A | Abutip formulation comprising lysine salt as tonicity modifier and use thereof | 济世发展生物药业有限公司 | 2020-06-30 | — | — | CN | disclosed |
| US-10695272-B2 | Compositions containing microcapsules coated with deposition proteins | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2020-06-30 | — | — | US | disclosed |
| WO-2020131956-A1 | HYDROXYETHYL CELLULOSE MICROCAPSULES | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2020-06-25 | — | — | WO | disclosed |
| WO-2020131855-A1 | GUAR GUM MICROCAPSULES | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2020-06-25 | — | — | WO | disclosed |
| WO-2020131875-A2 | MICROCAPSULES PREPARED FROM PROTEINS | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2020-06-25 | — | — | WO | disclosed |
| WO-2020131890-A1 | MICROCAPSULE COMPOSITIONS | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2020-06-25 | — | — | WO | disclosed |
| WO-2020131879-A2 | PROTEIN MICROCAPSULES AND METHOD OF PREPARING THE SAME | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2020-06-25 | — | — | WO | disclosed |
| WO-2020131866-A1 | MICROCAPSULE COMPOSITIONS PREPARED FROM POLYSACCHARIDES | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2020-06-25 | — | — | WO | disclosed |
| CN-107836502-B | Slicing device for squid | 浙江国际海运职业技术学院 | 2020-06-23 | — | — | CN | disclosed |
| US-20200170895-A1 | POLYUREA CAPSULE COMPOSITIONS | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2020-06-04 | — | — | US | disclosed |
| EP-3366680-B1 | DENDRIMER LIKE AMINO AMIDES POSSESSING SODIUM CHANNEL BLOCKER ACTIVITY FOR THE TREATMENT OF DRY EYE AND OTHER MUCOSAL DISEASES | PARION SCIENCES INC (US) | 2020-05-13 | — | — | EP | disclosed |
| CN-105722495-B | Polyurea or polyurethane capsules | 国际香料和香精公司 | 2020-02-28 | — | — | CN | disclosed |
| WO-2020037025-A1 | FABRIC TREATMENT COMPOSITIONS COMPRISING BENEFIT AGENT CAPSULES | THE PROCTER & GAMBLE COMPANY (US) | 2020-02-20 | — | — | WO | disclosed |
| WO-2020037026-A1 | FABRIC TREATMENT COMPOSITIONS COMPRISING BENEFIT AGENT CAPSULES | THE PROCTER & GAMBLE COMPANY (US) | 2020-02-20 | — | — | WO | disclosed |
| US-20200056126-A1 | FABRIC TREATMENT COMPOSITIONS COMPRISING BENEFIT AGENT CAPSULES | THE PROCTER & GAMBLE COMPANY | 2020-02-20 | — | — | US | disclosed |
| US-20200056123-A1 | LIQUID FABRIC TREATMENT COMPOSITIONS COMPRISING BRIGHTENER | THE PROCTER & GAMBLE COMPANY | 2020-02-20 | — | — | US | disclosed |
| WO-2020037027-A1 | LIQUID FABRIC TREATMENT COMPOSITIONS COMPRISING BRIGHTENER | THE PROCTER & GAMBLE COMPANY (US) | 2020-02-20 | — | — | WO | disclosed |
| US-20200054558-A1 | AEROSOL DELIVERY SYSTEMS, COMPOSITIONS AND METHODS | PARION SCIENCES, INC. (US) | 2020-02-20 | — | — | US | disclosed |
| US-20200056120-A1 | FABRIC TREATMENT COMPOSITIONS COMPRISING BENEFIT AGENT CAPSULES | THE PROCTER & GAMBLE COMPANY | 2020-02-20 | — | — | US | disclosed |
| EP-3611247-A1 | FABRIC TREATMENT COMPOSITIONS COMPRISING BENEFIT AGENT CAPSULES | The Procter & Gamble Company (US) | 2020-02-19 | — | — | EP | disclosed |
| EP-3611245-A1 | LIQUID FABRIC TREATMENT COMPOSITIONS COMPRISING BRIGHTENER | The Procter & Gamble Company (US) | 2020-02-19 | — | — | EP | disclosed |
| EP-3611246-A1 | FABRIC TREATMENT COMPOSITIONS COMPRISING BENEFIT AGENT CAPSULES | The Procter & Gamble Company (US) | 2020-02-19 | — | — | EP | disclosed |
| US-20200046616-A1 | POLYUREA OR POLYURETHANE CAPSULES | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2020-02-13 | — | — | US | disclosed |
| US-10555879-B2 | Polyurea capsule compositions | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2020-02-11 | — | — | US | disclosed |
| EP-3603612-A1 | STRATUM CORNEUM FUNCTION IMPROVING AGENT | Ajinomoto Co., Inc. (JP) | 2020-02-05 | — | — | EP | disclosed |
| US-20190308943-A1 | 3,5-DIAMINO-6-CHLORO-N-(N-(4-PHENYLBUTYL)CARBAMIMIDOYL) PYRAZINE-2- CARBOXAMIDE COMPOUNDS | PARION SCIENCES, INC. (US) | 2019-10-10 | — | — | US | disclosed |
| US-10434045-B2 | Polyurea or polyurethane capsules | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2019-10-08 | — | — | US | disclosed |
| EP-3035923-B1 | DITHIOL MUCOLYTIC AGENTS | PARION SCIENCES INC (US) | 2019-09-25 | — | — | EP | disclosed |
| US-20190270064-A1 | MICROCAPSULE COMPOSITIONS STABILIZED WITH VISCOSITY CONTROL AGENT | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2019-09-05 | — | — | US | disclosed |
| EP-3323812-B1 | ARYLALKYL-AND ARYLOXYALKYL-SUBSTITUTED EPITHELIAL SODIUM CHANNEL BLOCKING COMPOUNDS | PARION SCIENCES INC (US) | 2019-08-14 | — | — | EP | disclosed |
| US-20190231658-A1 | STABLE MICROCAPSULE COMPOSITIONS | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2019-08-01 | — | — | US | disclosed |
| US-20190224086-A1 | MICROCAPSULE COMPOSITIONS WITH IMPROVED DEPOSITION | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2019-07-25 | — | — | US | disclosed |
| EP-3512625-A1 | MICROCAPSULE COMPOSITIONS STABILIZED WITH VISCOSITY CONTROL AGENTS | International Flavors & Fragrances Inc. (US) | 2019-07-24 | — | — | EP | disclosed |
| US-10335558-B2 | Methods of treatment | PARION SCIENCES, INC. (US) | 2019-07-02 | — | — | US | disclosed |
| US-20190184364-A1 | FRAGRANCE COMPOSITIONS CONTAINING MICROCAPSULES | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2019-06-20 | — | — | US | disclosed |
| US-10309212-B2 | Energetic cocrystals for treatment of a subterranean formation | HALLIBURTON ENERGY SERVICES, INC. (US) | 2019-06-04 | — | — | US | disclosed |
| US-20190159979-A1 | RELOADABLE MICROCAPSULES | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2019-05-30 | — | — | US | disclosed |
| CN-109795989-A | A method of it obtaining hydrochloride aqueous solution from the hydrogen chloride solution of sulfur-bearing and prepares alkali salt hydrochlorate | 东南大学 | 2019-05-24 | — | — | CN | disclosed |
| EP-3478249-A1 | STABLE MICROCAPSULE COMPOSITIONS | International Flavors & Fragrances Inc. (US) | 2019-05-08 | — | — | EP | disclosed |
| US-10253244-B2 | Scale-inhibiting cocrystals for treatment of a subterranean formation | HALLIBURTON ENERGY SERVICES, INC. (US) | 2019-04-09 | — | — | US | disclosed |
| US-10246425-B2 | 3,5-diamino-6-chloro-N-(N-(4-phenylbutyl)carbamimidoyl) pyrazine-2-carboxamide compounds | PARION SCIENCES, INC. (US) | 2019-04-02 | — | — | US | disclosed |
| US-20190083407-A1 | CRYSTALLIZATION METHOD AND BIOAVAILABILITY | GRUNENTHAL GMBH (DE) | 2019-03-21 | — | — | US | disclosed |
| US-20190084943-A1 | CHLORO-PYRAZINE CARBOXAMIDE DERIVATIVES WITH EPITHELIAL SODIUM CHANNEL BLOCKING ACTIVITY | PARION SCIENCES, INC. (US) | 2019-03-21 | — | — | US | disclosed |
| US-10233158-B2 | Arylalkyl- and aryloxyalkyl-substituted epithelial sodium channel blocking compounds | PARION SCIENCES, INC. (US) | 2019-03-19 | — | — | US | disclosed |
| EP-3452004-A1 | RELOADABLE MICROCAPSULES | International Flavors & Fragrances Inc. (US) | 2019-03-13 | — | — | EP | disclosed |
| US-20190031679-A1 | NOVEL MONOTHIOL MUCOLYTIC AGENTS | PARION SCIENCES, INC. | 2019-01-31 | — | — | US | disclosed |
| EP-3428153-A1 | 3,5-DIAMINO-6-CHLORO-N-(N-(4-PHENYLBUTYL)CARBAMIMIDOYL) PYRAZINE-2- CARBOXAMIDE COMPOUNDS | Parion Sciences, Inc. (US) | 2019-01-16 | — | — | EP | disclosed |
| US-20190010132-A1 | ARYLALKYL-AND ARYLOXYALKYL-SUBSTITUTED EPITHELIAL SODIUM CHANNEL BLOCKING COMPOUNDS | PARION SCIENCES, INC. (US) | 2019-01-10 | — | — | US | disclosed |
| EP-3425036-A1 | BRANCHED POLYETHYLENEIMINE MICROCAPSULES | International Flavors & Fragrances Inc. (US) | 2019-01-09 | — | — | EP | disclosed |
| CN-208338774-U | The slicing device of squid | 浙江国际海运职业技术学院 | 2019-01-08 | — | — | CN | disclosed |
| EP-3416610-A1 | POLYUREA CAPSULE COMPOSITIONS | International Flavors & Fragrances Inc. (US) | 2018-12-26 | — | — | EP | disclosed |
| US-10159672-B2 | Chemically and metabolically stable dipeptide possessing potent sodium channel blocker activity | PARION SCIENCES, INC. (US) | 2018-12-25 | — | — | US | disclosed |
| US-20180353399-A1 | POLYUREA CAPSULE COMPOSITIONS | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2018-12-13 | — | — | US | disclosed |
| US-20180346648-A1 | BRANCHED POLYETHYLENEIMINE MICROCAPSULES | INTERNATIONAL FLAVORS AND FRAGRANCES INC. | 2018-12-06 | — | — | US | disclosed |
| US-20180325786-A1 | POLYUREA OR POLYURETHANE CAPSULES | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2018-11-15 | — | — | US | disclosed |
| US-10106551-B2 | Monothiol mucolytic agents | PARION SCIENCES, INC. (US) | 2018-10-23 | — | — | US | disclosed |
| US-10092486-B2 | Polyurea or polyurethane capsules | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2018-10-09 | — | — | US | disclosed |
| US-10093691-B2 | Crystallization method and bioavailability | GRUNENTHAL GMBH (DE) | 2018-10-09 | — | — | US | disclosed |
| US-10085925-B2 | Polyurea capsule compositions | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2018-10-02 | — | — | US | disclosed |
| CN-108580377-A | Copepods biological feed automatic flushing device | 浙江海洋大学 | 2018-09-28 | — | — | CN | disclosed |
| US-20180272308-A1 | HYBRID CAPSULES | INT FLAVORS & FRAGRANCES INC (US) | 2018-09-27 | — | — | US | disclosed |
| US-10071970-B2 | Chloro-pyrazine carboxamide derivatives with epithelial sodium channel blocking activity | PARION SCIENCES, INC. (US) | 2018-09-11 | — | — | US | disclosed |
| US-20180250204-A1 | COMPOSITIONS CONTAINING MICROCAPSULES COATED WITH DEPOSITION PROTEINS | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2018-09-06 | — | — | US | disclosed |
| EP-3366680-A1 | DENDRIMER LIKE AMINO AMIDES POSSESSING SODIUM CHANNEL BLOCKER ACTIVITY FOR THE TREATMENT OF DRY EYE AND OTHER MUCOSAL DISEASES | Parion Sciences, Inc. (US) | 2018-08-29 | — | — | EP | disclosed |
| EP-3362071-A1 | CRYSTALLIZATION METHOD AND BIOAVAILABILITY | Grünenthal GmbH (DE) | 2018-08-22 | — | — | EP | disclosed |
| EP-3356449-A1 | HYBRID CAPSULES | International Flavors & Fragrances Inc. (US) | 2018-08-08 | — | — | EP | disclosed |
| US-10021789-B2 | Metal-laminated polyimide substrate, and method for production thereof | EBARA-UDYLITE CO., LTD. (JP) | 2018-07-10 | — | — | US | disclosed |
| US-9987443-B2 | Inhaled hypertonic saline delivered by a heated nasal cannula | PARION SCIENCES, INC. (US) | 2018-06-05 | — | — | US | disclosed |
| EP-3323812-A1 | ARYLALKYL-AND ARYLOXYALKYL-SUBSTITUTED EPITHELIAL SODIUM CHANNEL BLOCKING COMPOUNDS | Parion Sciences, Inc. (US) | 2018-05-23 | — | — | EP | disclosed |
| US-9974720-B2 | Compositions containing microcapsules coated with deposition proteins | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2018-05-22 | — | — | US | disclosed |
| US-9963427-B2 | Dithiol mucolytic agents | PARION SCIENCES, INC. (US) | 2018-05-08 | — | — | US | disclosed |
| US-9957238-B2 | Arylalkyl-and aryloxyalkyl-substituted epithelial sodium channel blocking compounds | PARION SCIENCES, INC. (US) | 2018-05-01 | — | — | US | disclosed |
| US-20180111907-A1 | DENDRIMER LIKE AMINO AMIDES POSSESSING SODIUM CHANNEL BLOCKER ACTIVITY FOR THE TREATMENT OF DRY EYE AND OTHER MUCOSAL DISEASES | PARION SCIENCES, INC. | 2018-04-26 | — | — | US | disclosed |
| US-20180104241-A1 | CHEMICALLY AND METABOLICALLY STABLE DIPEPTIDE POSSESSING POTENT SODIUM CHANNEL BLOCKER ACTIVITY | PARION SCIENCES, INC. (US) | 2018-04-19 | — | — | US | disclosed |
| EP-2855435-B1 | DENDRIMER LIKE AMINO AMIDES POSSESSING SODIUM CHANNEL BLOCKER ACTIVITY FOR THE TREATMENT OF DRY EYE AND OTHER MUCOSAL DISEASES | PARION SCIENCES INC (US) | 2018-04-11 | — | — | EP | disclosed |
| EP-3300794-A2 | MICROCAPSULE COMPOSITIONS CONTAINING AMINO SILICONE | International Flavors & Fragrances Inc. (US) | 2018-04-04 | — | — | EP | disclosed |
| US-20180085291-A1 | MICROCAPSULE COMPOSITIONS CONTAINING AMINO SILICONE | INTERNATIONAL FLAVORS AND FRAGRANCES INC. | 2018-03-29 | — | — | US | disclosed |
| CN-107836502-A | the slicing device of squid | 浙江国际海运职业技术学院 | 2018-03-27 | — | — | CN | disclosed |
| WO-2018053356-A1 | MICROCAPSULE COMPOSITIONS STABILIZED WITH VISCOSITY CONTROL AGENTS | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2018-03-22 | — | — | WO | disclosed |
| EP-2931712-B1 | 3,5-DIAMINO-6-CHLORO-N-(N-(4-PHENYLBUTYL)CARBAMIMIDOYL) PYRAZINE-2- CARBOXAMIDE COMPOUNDS | PARION SCIENCES INC (US) | 2018-03-21 | — | — | EP | disclosed |
| US-20180064615-A1 | RELOADABLE MICROCAPSULES | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2018-03-08 | — | — | US | disclosed |
| EP-3288548-A1 | NOVEL PRODRUGS OF DITHIOL MUCOLYTIC AGENTS | Parion Sciences, Inc. (US) | 2018-03-07 | — | — | EP | disclosed |
| US-20180042825-A1 | MICROCAPSULE COMPOSITIONS WITH HIGH PERFORMANCE | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2018-02-15 | — | — | US | disclosed |
| US-9878988-B2 | Dendrimer like amino amides possessing sodium channel blocker activity for the treatment of dry eye and other mucosal diseases | PARION SCIENCES, INC. (US) | 2018-01-30 | — | — | US | disclosed |
| US-20180015009-A1 | MICROCAPSULE COMPOSITIONS WITH IMPROVED DEPOSITION | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2018-01-18 | — | — | US | disclosed |
| EP-3265065-A1 | MICROCAPSULE COMPOSITIONS WITH HIGH PERFORMANCE | International Flavors & Fragrances Inc. (US) | 2018-01-10 | — | — | EP | disclosed |
| WO-2018006089-A1 | STABLE MICROCAPSULE COMPOSITIONS | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2018-01-04 | — | — | WO | disclosed |
| US-9856224-B2 | Stable sodium channel blockers | PARION SCIENCES, INC. (US) | 2018-01-02 | — | — | US | disclosed |
| US-20170362187-A1 | 3,5-DIAMINO-6-CHLORO-N-(N-(4-PHENYLBUTYL)CARBAMIMIDOYL) PYRAZINE-2- CARBOXAMIDE COMPOUNDS | PARION SCIENCES, INC. (US) | 2017-12-21 | — | — | US | disclosed |
| EP-3250548-A1 | NOVEL MONOTHIOL MUCOLYTIC AGENTS | Parion Sciences, Inc. (US) | 2017-12-06 | — | — | EP | disclosed |
| US-20170334864-A1 | 3,5-DIAMINO-6-CHLORO-N-(N-(4-(4-(2-(HEXYL(2,3,4,5,6-PENTAHYDROXYHEXYL)AMINO)ETHOXY)PHENYL)BUTYL) CARBAMIMIDOYL)PYRAZINE-2-CARBOXAMIDE | PARION SCIENCES, INC. (US) | 2017-11-23 | — | — | US | disclosed |
| US-20170327472-A1 | CHLORO-PYRAZINE CARBOXAMIDE DERIVATIVES WITH EPITHELIAL SODIUM CHANNEL BLOCKING ACTIVITY | PARION SCIENCES, INC. (US) | 2017-11-16 | — | — | US | disclosed |
| US-9816059-B2 | Stabilized capsule compositions | INTERNATIONAL FLAVORS & FRAGRANCES (US) | 2017-11-14 | — | — | US | disclosed |
| WO-2017192648-A1 | RELOADABLE MICROCAPSULES | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2017-11-09 | — | — | WO | disclosed |
| US-20170305868-A1 | ARYLALKYL-AND ARYLOXYALKYL-SUBSTITUTED EPITHELIAL SODIUM CHANNEL BLOCKING COMPOUNDS | PARION SCIENCES, INC. (US) | 2017-10-26 | — | — | US | disclosed |
| US-20170281620-A1 | CHEMICALLY AND METABOLICALLY STABLE DIPEPTIDE POSSESSING POTENT SODIUM CHANNEL BLOCKER ACTIVITY | PARION SCIENCES, INC. (US) | 2017-10-05 | — | — | US | disclosed |
| US-20170267649-A1 | STABLE SODIUM CHANNEL BLOCKERS | PARION SCIENCES, INC. (US) | 2017-09-21 | — | — | US | disclosed |
| US-20170252274-A1 | POLYUREA CAPSULES PREPARED WITH ALIPHATIC ISOCYANATES AND AMINES | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2017-09-07 | — | — | US | disclosed |
| WO-2017143174-A1 | POLYUREA CAPSULE COMPOSITIONS | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2017-08-24 | — | — | WO | disclosed |
| EP-3200750-A1 | CAPSULES CONTAINING POLYVINYL ALCOHOL | International Flavors & Fragrances Inc. (US) | 2017-08-09 | — | — | EP | disclosed |
| US-20170216166-A1 | CAPSULES CONTAINING POLYVINYL ALCOHOL | INT FLAVORS & FRAGRANCES INC (US) | 2017-08-03 | — | — | US | disclosed |
| EP-2931711-B1 | ARYLALKYL-AND ARYLOXYALKYL-SUBSTITUTED EPITHELIAL SODIUM CHANNEL BLOCKING COMPOUNDS | PARION SCIENCES INC (US) | 2017-08-02 | — | — | EP | disclosed |
| US-20170189283-A1 | COMPOSITIONS CONTAINING MICROCAPSULES COATED WITH DEPOSITION PROTEINS | INTERNATIONAL FLAVORS AND FRAGRANCES INC. | 2017-07-06 | — | — | US | disclosed |
| US-9695134-B2 | 3,5-diamino-6-chloro-N-(n-(4-phenylbutyl)carbamimidoyl)pyrazine-2-carboxamide compounds | PARION SCIENCES, INC. (US) | 2017-07-04 | — | — | US | disclosed |
| US-9687424-B2 | Polyurea capsules prepared with aliphatic isocyanates and amines | INTERNATIONAL FLAVORS & FRAGRANCES (US) | 2017-06-27 | — | — | US | disclosed |
| US-20170151396-A1 | INHALED HYPERTONIC SALINE DELIVERED BY A HEATED NASAL CANNULA | PARION SCIENCES, INC. (US) | 2017-06-01 | — | — | US | disclosed |
| US-9655896-B2 | Chemically and metabolically stable dipeptide possessing potent sodium channel blocker activity | PARION SCIENCES, INC. (US) | 2017-05-23 | — | — | US | disclosed |
| EP-2723176-B1 | A CHEMICALLY AND METABOLICALLY STABLE DIPEPTIDE POSSESSING POTENT SODIUM CHANNEL BLOCKER ACTIVITY | PARION SCIENCES INC (US) | 2017-04-12 | — | — | EP | disclosed |
| EP-3150585-A1 | CHLORO-PYRAZINE CARBOXAMIDE DERIVATIVES WITH EPITHELIAL SODIUM CHANNEL BLOCKING ACTIVITY | Parion Sciences, Inc. (US) | 2017-04-05 | — | — | EP | disclosed |
| WO-2017049294-A1 | CRYSTALLIZATION METHOD AND BIOAVAILABILITY | THAR PHARMACEUTICALS, INC. (US) | 2017-03-23 | — | — | WO | disclosed |
| US-9593084-B2 | Chloro-pyrazine carboxamide derivatives with epithelial sodium channel blocking activity | PARION SCIENCES, INC. (US) | 2017-03-14 | — | — | US | disclosed |
| US-9586911-B2 | Arylalkyl- and aryloxyalkyl-substituted epthelial sodium channel blocking compounds | PARION SCIENCES, INC. (US) | 2017-03-07 | — | — | US | disclosed |
| US-9586910-B2 | 3,5-diamino-6-chloro-N-(N-(4-(4-(2-(hexyl(2,3,4,5,6-pentahydroxyhexyl)amino)ethoxy)phenyl)butyl)carbamimidoyl)pyrazine-2-carboxamide | PARION SCIENCES, INC. (US) | 2017-03-07 | — | — | US | disclosed |
| US-20170022227-A1 | CRYSTALLIZATION METHOD AND BIOAVAILABILITY | THAR PHARMACEUTICALS, INC. (US) | 2017-01-26 | — | — | US | disclosed |
| CN-106222231-A | Method for rapidly producing high-optical-purity D-lysine | 南京工业大学 | 2016-12-14 | — | — | CN | disclosed |
| US-20160318861-A1 | NOVEL PRODRUGS OF DITHIOL MUCOLYTIC AGENTS | PARION SCIENCES, INC. (US) | 2016-11-03 | — | — | US | disclosed |
| WO-2016176423-A1 | NOVEL PRODRUGS OF DITHIOL MUCOLYTIC AGENTS | PARION SCIENCES, INC. (US) | 2016-11-03 | — | — | WO | disclosed |
| EP-2931713-B1 | CHLORO-PYRAZINE CARBOXAMIDE DERIVATIVES USEFUL FOR THE TREATMENT OF DISEASES FAVOURED BY INSUFFICIENT MUCOSAL HYDRATION | PARION SCIENCES INC (US) | 2016-10-19 | — | — | EP | disclosed |
| US-20160289262-A1 | BILE ACID DERIVATIVES AS FXR/TGR5 AGONISTS AND METHODS OF USE THEREOF | ENANTA PHARMACEUTICALS, INC. | 2016-10-06 | — | — | US | disclosed |
| WO-2016144798-A1 | MICROCAPSULE COMPOSITIONS WITH HIGH PERFORMANCE | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2016-09-15 | — | — | WO | disclosed |
| US-9408988-B2 | Inhaled hypertonic saline delivered by a heated nasal cannula | PARION SCIENCES, INC. (US) | 2016-08-09 | — | — | US | disclosed |
| US-20160222023-A1 | NOVEL MONOTHIOL MUCOLYTIC AGENTS | PARION SCIENCES, INC. (US) | 2016-08-04 | — | — | US | disclosed |
| WO-2016123335-A1 | NOVEL MONOTHIOL MUCOLYTIC AGENTS | PARION SCIENCES, INC. (US) | 2016-08-04 | — | — | WO | disclosed |
| US-20160194278-A1 | DITHIOL MUCOLYTIC AGENTS | PARION SCIENCES, INC. (US) | 2016-07-07 | — | — | US | disclosed |
| US-20160193122-A1 | POLYUREA OR POLYURETHANE CAPSULES | INTERNATIONAL FLAVORS AND FRAGRANCES INC. | 2016-07-07 | — | — | US | disclosed |
| EP-3035923-A2 | DITHIOL MUCOLYTIC AGENTS | Parion Sciences, Inc. (US) | 2016-06-29 | — | — | EP | disclosed |
| US-20160177698-A1 | ENERGETIC COCRYSTALS FOR TREATMENT OF A SUBTERRANEAN FORMATION | HALLIBURTON ENERGY SERVICES, INC. | 2016-06-23 | — | — | US | disclosed |
| EP-3034497-A1 | 3,5-DIAMINO-6-CHLORO-N-(N-(4-(4-(2-(HEXYL(2,3,4,5,6-PENTA-HYDROXYHEXYL)AMINO)ETHOXY)PHENYL)BUTYL) CARBAMIMIDOYL)PYRAZINE-2-CARBOXAMIDE | Parion Sciences, Inc. (US) | 2016-06-22 | — | — | EP | disclosed |
| EP-3033066-A1 | POLYUREA OR POLYURETHANE CAPSULES | International Flavors & Fragrances Inc. (US) | 2016-06-22 | — | — | EP | disclosed |
| US-20160166480-A1 | MICROCAPSULE COMPOSITIONS | INTERNATIONAL FLAVORS AND FRAGRANCES INC. | 2016-06-16 | — | — | US | disclosed |
| US-20160158121-A1 | POLYUREA CAPSULE COMPOSITIONS | INTERNATIONAL FLAVORS AND FRAGRANCES INC. | 2016-06-09 | — | — | US | disclosed |
| US-9346753-B2 | Dithiol mucolytic agents | PARION SCIENCES, INC. (US) | 2016-05-24 | — | — | US | disclosed |
| US-20160130496-A1 | SCALE-INHIBITING COCRYSTALS FOR TREATMENT OF A SUBTERRANEAN FORMATION | HALLIBURTON ENERGY SERVICES, INC. | 2016-05-12 | — | — | US | disclosed |
| US-20160122306-A1 | DENDRIMER LIKE AMINO AMIDES POSSESSING SODIUM CHANNEL BLOCKER ACTIVITY FOR THE TREATMENT OF DRY EYE AND OTHER MUCOSAL DISEASES | PARION SCIENCES, INC. (US) | 2016-05-05 | — | — | US | disclosed |
| EP-2292585-B1 | Screening for solid forms by ultrasound crystallization and cocrystallization using ultrasound | APTUIT WEST LAFAYETTE LLC (US) | 2016-04-27 | — | — | EP | disclosed |
| WO-2016054351-A1 | CAPSULES CONTAINING POLYVINYL ALCOHOL | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2016-04-07 | — | — | WO | disclosed |
| US-9260398-B2 | Dendrimer like amino amides possessing sodium channel blocker activity for the treatment of dry eye and other mucosal diseases | PARION SCIENCES, INC. (US) | 2016-02-16 | — | — | US | disclosed |
| US-20160016982-A1 | CRYSTALLIZATION METHOD AND BIOAVAILABILITY | THAR PHARMACEUTICALS, INC. (US) | 2016-01-21 | — | — | US | disclosed |
| US-20150376145-A1 | STABLE SODIUM CHANNEL BLOCKERS | PARION SCIENCES, INC. (US) | 2015-12-31 | — | — | US | disclosed |
| US-20150307530-A1 | NOVEL MUCOLYTIC AGENTS | PARION SCIENCES, INC. (US) | 2015-10-29 | — | — | US | disclosed |
| US-9169279-B2 | Crystallization method and bioavailability | THAR PHARMACEUTICALS, INC. (US) | 2015-10-27 | — | — | US | disclosed |
| US-20150299142-A1 | 3,5-DIAMINO-6-CHLORO-N-(4-PHENYLBUTYL)CARBAMIMIDOYL) PYRAZINE-2-CARBOXAMIDE COMPOUNDS | PARION SCIENCES, INC. (US) | 2015-10-22 | — | — | US | disclosed |
| EP-2931712-A1 | 3,5-DIAMINO-6-CHLORO-N-(N-(4-PHENYLBUTYL)CARBAMIMIDOYL) PYRAZINE-2- CARBOXAMIDE COMPOUNDS | Parion Sciences, Inc. (US) | 2015-10-21 | — | — | EP | disclosed |
| EP-2931711-A1 | ARYLALKYL-AND ARYLOXYALKYL-SUBSTITUTED EPITHELIAL SODIUM CHANNEL BLOCKING COMPOUNDS | Parion Sciences, Inc. (US) | 2015-10-21 | — | — | EP | disclosed |
| EP-2931713-A1 | CHLORO-PYRAZINE CARBOXAMIDE DERIVATIVES USEFUL FOR THE TREATMENT OF DISEASES FAVOURED BY INSUFFICIENT MUCOSAL HYDRATION | Parion Sciences, Inc. (US) | 2015-10-21 | — | — | EP | disclosed |
| US-20150290189-A1 | CHEMICALLY AND METABOLICALLY STABLE DIPEPTIDE POSSESSING POTENT SODIUM CHANNEL BLOCKER ACTIVITY | PARION SCIENCES, INC. (US) | 2015-10-15 | — | — | US | disclosed |
| EP-2928532-A1 | NASAL CANNULA FOR DELIVERY OF AEROSOLIZED MEDICAMENTS | Parion Sciences, Inc. (US) | 2015-10-14 | — | — | EP | disclosed |
| US-20150268248-A1 | CELL SELECTIVE PROTEOME LABELING | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2015-09-24 | — | — | US | disclosed |
| US-20150252312-A1 | STABILIZED CAPSULE COMPOSITIONS | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2015-09-10 | — | — | US | disclosed |
| EP-2723722-B1 | 3,5-DIAMINO-6-CHLORO-N-(N-(4-(4-(2-(HEXYL (2,3,4,5,6-PENTAHYDROXYHEXYL) AMINO) ETHOXY) PHENYL) BUTYL) CARBAMIMIDOYL) PYRAZINE-2-CARBOXAMIDE | PARION SCIENCES INC (US) | 2015-09-09 | — | — | EP | disclosed |
| CN-103204783-B | A kind of preparation method of D-lysine hydrochloride | HUACHANG PHARMACEUTICAL CO., LTD., ZHANGJIAGANG CITY (CN) | 2015-09-02 | — | — | CN | disclosed |
| CN-103204783-B | A kind of preparation method of D-lysine hydrochloride | HUACHANG PHARMACEUTICAL CO., LTD., ZHANGJIAGANG CITY (CN) | 2015-09-02 | — | — | CN | disclosed |
| CN-103204783-B | A kind of preparation method of D-lysine hydrochloride | HUACHANG PHARMACEUTICAL CO., LTD., ZHANGJIAGANG CITY (CN) | 2015-09-02 | — | — | CN | disclosed |
| CN-104857002-A | Chiral isomeric compound included lysine vitamin drug composition and application thereof | LIU LI | 2015-08-26 | — | — | CN | disclosed |
| US-9102633-B2 | Arylalkyl- and aryloxyalkyl-substituted epithelial sodium channel blocking compounds | PARION SCIENCES, INC. (US) | 2015-08-11 | — | — | US | disclosed |
| EP-2893033-A2 | CELL SELECTIVE PROTEOME LABELING | Memorial Sloan-Kettering Cancer Center (US) | 2015-07-15 | — | — | EP | disclosed |
| US-9072738-B2 | Chemically and metabolically stable dipeptide possessing potent sodium channel blocker activity | PARION SCIENCES, INC. (US) | 2015-07-07 | — | — | US | disclosed |
| CN-104739816-A | Lysine-gluconate-zinc pharmaceutical composition comprising chiral heterogeneous compound and application of lysine-gluconate-zinc pharmaceutical composition comprising chiral heterogeneous compound | LIU LI | 2015-07-01 | — | — | CN | disclosed |
| US-20150166488-A1 | ARYLALKYL- AND ARYLOXYALKYL-SUBSTITUTED EPTHELIAL SODIUM CHANNEL BLOCKING COMPOUNDS | PARION SCIENCES, INC. (US) | 2015-06-18 | — | — | US | disclosed |
| US-20150166487-A1 | ARYLALKYL- AND ARYLOXYALKYL-SUBSTITUTED EPITHELIAL SODIUM CHANNEL BLOCKING COMPOUNDS | PARION SCIENCES, INC. (US) | 2015-06-18 | — | — | US | disclosed |
| CN-104706669-A | Diavitamin calcium lysinate pharmaceutical composition containing chiral isocompound and application of pharmaceutical composition | LIU LI | 2015-06-17 | — | — | CN | disclosed |
| CN-104688774-A | Lysine and calcium hydrophosphate pharmaceutical composition comprising chiral isomeric compound and application of pharmaceutical composition | HU LIFANG | 2015-06-10 | — | — | CN | disclosed |
| CN-104688763-A | Lysine-vitamin pharmaceutical composition containing chiral isocompounds and use thereof | LIU LI | 2015-06-10 | — | — | CN | disclosed |
| US-20150150803-A1 | AEROSOL DELIVERY SYSTEMS, COMPOSITIONS AND METHODS | PARION SCIENCES, INC. (US) | 2015-06-04 | — | — | US | disclosed |
| US-9029382-B2 | 3,5-diamino-6-chloro-N-(N-(4-phenylbutyl)carbamimidoyl) pyrazine-2-carboxamide compounds | PARION SCIENCES, INC. (US) | 2015-05-12 | — | — | US | disclosed |
| US-20150101597-A1 | METHODS OF TREATMENT | PARION SCIENCES, INC. (US) | 2015-04-16 | — | — | US | disclosed |
| US-20150099764-A1 | DENDRIMER LIKE AMINO AMIDES POSSESSING SODIUM CHANNEL BLOCKER ACTIVITY FOR THE TREATMENT OF DRY EYE AND OTHER MUCOSAL DISEASES | PARION SCIENCES, INC. (US) | 2015-04-09 | — | — | US | disclosed |
| EP-2855435-A2 | DENDRIMER LIKE AMINO AMIDES POSSESSING SODIUM CHANNEL BLOCKER ACTIVITY FOR THE TREATMENT OF DRY EYE AND OTHER MUCOSAL DISEASES | Parion Sciences, Inc. (US) | 2015-04-08 | — | — | EP | disclosed |
| US-8980898-B2 | Dendrimer like amino amides possessing sodium channel blocker activity for the treatment of dry eye and other mucosal diseases | PARION SCIENCES, INC. (US) | 2015-03-17 | — | — | US | disclosed |
| WO-2015034478-A1 | SCALE-INHIBITING COCRYSTALS FOR TREATMENT OF A SUBTERRANEAN FORMATION | HALLIBURTON ENERGY SERVICES, INC. (US) | 2015-03-12 | — | — | WO | disclosed |
| WO-2015030730-A1 | ENERGETIC COCRYSTALS FOR TREATMENT OF A SUBTERRANEAN FORMATION | HALLIBURTON ENERGY SERVICES, INC. (US) | 2015-03-05 | — | — | WO | disclosed |
| EP-2841138-A2 | AEROSOL DELIVERY SYSTEMS, COMPOSITIONS AND METHODS | Parion Sciences, Inc. (US) | 2015-03-04 | — | — | EP | disclosed |
| WO-2015026601-A2 | DITHIOL MUCOLYTIC AGENTS | JOHNSON MICHAEL R (US) | 2015-02-26 | — | — | WO | disclosed |
| US-20150056305-A1 | DITHIOL MUCOLYTIC AGENTS | PARION SCIENCES, INC. (US) | 2015-02-26 | — | — | US | disclosed |
| WO-2015023961-A1 | POLYUREA OR POLYURETHANE CAPSULES | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2015-02-19 | — | — | WO | disclosed |
| US-8945605-B2 | Aerosol delivery systems, compositions and methods | PARION SCIENCES, INC. (US) | 2015-02-03 | — | — | US | disclosed |
| US-8920559-B2 | Screening for solid forms by ultrasound crystallization and cocrystallization using ultrasound | APTUIT (WEST LAFAYETTE), LLC (US) | 2014-12-30 | — | — | US | disclosed |
| US-8778383-B2 | Methods of treatment | PARION SCIENCES, INC. (US) | 2014-07-15 | — | — | US | disclosed |
| WO-2014099676-A1 | CHLORO-PYRAZINE CARBOXAMIDE DERIVATIVES USEFUL FOR THE TREATMENT OF DISEASES FAVOURED BY INSUFFICIENT MUCOSAL HYDRATION | PARION SCIENCES, INC. (US) | 2014-06-26 | — | — | WO | disclosed |
| WO-2014099705-A1 | ARYLALKYL-AND ARYLOXYALKYL-SUBSTITUTED EPITHELIAL SODIUM CHANNEL BLOCKING COMPOUNDS | PARION SCIENCES, INC. (US) | 2014-06-26 | — | — | WO | disclosed |
| WO-2014099673-A1 | 3,5-DIAMINO-6-CHLORO-N-(N-(4-PHENYLBUTYL)CARBAMIMIDOYL) PYRAZINE-2- CARBOXAMIDE COMPOUNDS | PARION SCIENCES, INC. (US) | 2014-06-26 | — | — | WO | disclosed |
| US-20140170244-A1 | 3,5-DIAMINO-6-CHLORO-N-(N-(4-PHENYLBUTYL)CARBAMIMIDOYL) PYRAZINE-2- CARBOXAMIDE COMPOUNDS | PARION SCIENCES, INC. (US) | 2014-06-19 | — | — | US | disclosed |
| US-20140171447-A1 | CHLORO-PYRAZINE CARBOXAMIDE DERIVATIVES WITH EPITHELIAL SODIUM CHANNEL BLOCKING ACTIVITY | PARION SCIENCES, INC. (US) | 2014-06-19 | — | — | US | disclosed |
| US-20140158127-A1 | NASAL CANNULA FOR DELIVERY OF AEROSOLIZED MEDICAMENTS | PARION SCIENCES, INC. (US) | 2014-06-12 | — | — | US | disclosed |
| WO-2014089506-A1 | NASAL CANNULA FOR DELIVERY OF AEROSOLIZED MEDICAMENTS | BOUCHER PAUL (US) | 2014-06-12 | — | — | WO | disclosed |
| US-20140142118-A1 | CHEMICALLY AND METABOLICALLY STABLE DIPEPTIDE POSSESSING POTENT SODIUM CHANNEL BLOCKER ACTIVITY | PARION SCIENCES, INC. (US) | 2014-05-22 | — | — | US | disclosed |
| EP-2257296-B1 | POLY AROMATIC SODIUM CHANNEL BLOCKERS | PARION SCIENCES INC (US) | 2014-05-07 | — | — | EP | disclosed |
| EP-2723176-A1 | A CHEMICALLY AND METABOLICALLY STABLE DIPEPTIDE POSSESSING POTENT SODIUM CHANNEL BLOCKER ACTIVITY | Parion Sciences, Inc. (US) | 2014-04-30 | — | — | EP | disclosed |
| US-20140109899-A1 | AEROSOL DELIVERY SYSTEMS, COMPOSITIONS AND METHODS | PARION SCIENCES, INC. (US) | 2014-04-24 | — | — | US | disclosed |
| US-20140107133-A1 | 3,5-DIAMINO-6-CHLORO-N-(N-(4-(4-(2-(HEXYL(2,3,4,5,6-PENTAHYDROXYHEXYL)AMINO)ETHOXY)PHENYL)BUTYL)CARBAMIMIDOYL)PYRAZINE-2-CARBOXAMIDE | PARION SCIENCES, INC. (US) | 2014-04-17 | — | — | US | disclosed |
| EP-2717855-A1 | METHODS OF TREATMENT | Parion Sciences, Inc. (US) | 2014-04-16 | — | — | EP | disclosed |
| CN-102766060-B | Preparation method of D-lysine hydrochloride | CHENGDU BAISHIXING SCIENCE AND TECHNOLOGY INDUSTRY CO LTD | 2014-04-16 | — | — | CN | disclosed |
| CN-102766060-B | Preparation method of D-lysine hydrochloride | CHENGDU BAISHIXING SCIENCE AND TECHNOLOGY INDUSTRY CO LTD | 2014-04-16 | — | — | CN | disclosed |
| CN-102766060-B | Preparation method of D-lysine hydrochloride | CHENGDU BAISHIXING SCIENCE AND TECHNOLOGY INDUSTRY CO LTD | 2014-04-16 | — | — | CN | disclosed |
| US-20140096765-A1 | INHALED HYPERTONIC SALINE DELIVERED BY A HEATED NASAL CANNULA | PARION SCIENCES, INC. (US) | 2014-04-10 | — | — | US | disclosed |
| WO-2014039643-A2 | CELL SELECTIVE PROTEOME LABELING | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2014-03-13 | — | — | WO | disclosed |
| US-8669262-B2 | 3,5-diamino-6-chloro-N-(N-(4-(4-(2-(hexyl(2,3,4,5,6-pentahydroxyhexyl)amino)ethoxy)phenyl)butyl)carbamimidoyl)pyrazine-2-carboxamide | PARION SCIENCES, INC. (US) | 2014-03-11 | — | — | US | disclosed |
| WO-2014036445-A2 | NOVEL MUCOLYTIC AGENTS | JOHNSON MICHAEL R (US) | 2014-03-06 | — | — | WO | disclosed |
| US-20140031371-A1 | POLY AROMATIC SODIUM CHANNEL BLOCKERS | PARION SCIENCES, INC. (US) | 2014-01-30 | — | — | US | disclosed |
| US-20130337023-A1 | POLYUREA CAPSULES PREPARED WITH ALIPHATIC ISOCYANATES AND AMINES | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2013-12-19 | — | — | US | disclosed |
| WO-2013181232-A2 | DENDRIMER LIKE AMINO AMIDES POSSESSING SODIUM CHANNEL BLOCKER ACTIVITY FOR THE TREATMENT OF DRY EYE AND OTHER MUCOSAL DISEASES | JOHNSON MICHAEL ROSS (US) | 2013-12-05 | — | — | WO | disclosed |
| US-20130324559-A1 | DENDRIMER LIKE AMINO AMIDES POSSESSING SODIUM CHANNEL BLOCKER ACTIVITY FOR THE TREATMENT OF DRY EYE AND OTHER MUCOSAL DISEASES | PARION SCIENCES, INC. (US) | 2013-12-05 | — | — | US | disclosed |
| US-8575176-B2 | Heteroaromatic pyrazinoylguanidine sodium channel blockers | PARION SCIENCES, INC. (US) | 2013-11-05 | — | — | US | disclosed |
| WO-2013163517-A2 | AEROSOL DELIVERY SYSTEMS, COMPOSITIONS AND METHODS | PARION SCIENCES, INC. (US) | 2013-10-31 | — | — | WO | disclosed |
| US-8551534-B2 | Inhaled hypertonic saline delivered by a heated nasal cannula | PARION SCIENCES, INC. (US) | 2013-10-08 | — | — | US | disclosed |
| CN-103333087-A | Nalpha-fluorenylmethyloxycarbonyl-Nepsilon- fluorenylmethyloxycarbonyl-lysine preparation method | GL BIOCHEM SHANGHAI CO LTD | 2013-10-02 | — | — | CN | disclosed |
| CN-103204783-A | Preparation method of D-lysine hydrochloride | ZHANGJIAGANG HUACHANG PHARMACEUTICAL CO LTD | 2013-07-17 | — | — | CN | disclosed |
| CN-103204783-A | Preparation method of D-lysine hydrochloride | ZHANGJIAGANG HUACHANG PHARMACEUTICAL CO LTD | 2013-07-17 | — | — | CN | disclosed |
| CN-103204783-A | Preparation method of D-lysine hydrochloride | ZHANGJIAGANG HUACHANG PHARMACEUTICAL CO LTD | 2013-07-17 | — | — | CN | disclosed |
| US-20130178482-A1 | 3,5-DIAMINO-6-CHLORO-N-(N-(4-(4-(2-(HEXYL(2,3,4,5,6-PENTAHYDROXYHEXYL)AMINO)ETHOXY)PHENYL)BUTYL) CARBAMIMIDOYL)PYRAZINE-2-CARBOXAMIDE | PARION SCIENCES, INC. (US) | 2013-07-11 | — | — | US | disclosed |
| CN-103073498-A | Novel preparation method for (R)-Alpha-amino-e-caprolactam | BEIJING D VENTUREPHARM T CORP | 2013-05-01 | — | — | CN | disclosed |
| US-20130074842-A1 | METHODS OF TREATMENT | PARION SCIENCES, INC. | 2013-03-28 | — | — | US | disclosed |
| US-20130035315-A1 | CRYSTALLIZATION METHOD AND BIOAVAILABILITY | THAR PHARMA, LLC | 2013-02-07 | — | — | US | disclosed |
| US-8354014-B2 | Palladium complex and catalyst-imparting treatment solution using the same | EBARA-UDYLITE CO., LTD. (JP) | 2013-01-15 | — | — | US | disclosed |
| US-8350085-B2 | Cocrystallization | NEW FORM PHARMACEUTICALS INC. (US) | 2013-01-08 | — | — | US | disclosed |
| WO-2013003444-A1 | A CHEMICALLY AND METABOLICALLY STABLE DIPEPTIDE POSSESSING POTENT SODIUM CHANNEL BLOCKER ACTIVITY | JOHNSON MICHAEL ROSS (US) | 2013-01-03 | — | — | WO | disclosed |
| WO-2012170677-A1 | METHODS OF TREATMENT | PARION SCIENCES, INC. (US) | 2012-12-13 | — | — | WO | disclosed |
| CN-102766060-A | Preparation method of D-lysine hydrochloride | CHENGDU BAISHIXING SCIENCE AND TECHNOLOGY INDUSTRY CO LTD | 2012-11-07 | — | — | CN | disclosed |
| CN-102766060-A | Preparation method of D-lysine hydrochloride | CHENGDU BAISHIXING SCIENCE AND TECHNOLOGY INDUSTRY CO LTD | 2012-11-07 | — | — | CN | disclosed |
| CN-102766060-A | Preparation method of D-lysine hydrochloride | CHENGDU BAISHIXING SCIENCE AND TECHNOLOGY INDUSTRY CO LTD | 2012-11-07 | — | — | CN | disclosed |
| CN-101688308-B | Metal-laminated polyimide substrate, and method for production thereof | EBARA UDYLITE KK | 2012-10-10 | — | — | CN | disclosed |
| US-8252783-B2 | Quinolone carboxylic acids, derivatives thereof, and methods of making and using same | BAUSCH & LOMB INCORPORATED (US) | 2012-08-28 | — | — | US | disclosed |
| US-8221772-B2 | 1,2-Dipalmitoyl-sn-glycero-3-phosphocholine, 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoglycerol, palmitic acid or polypeptide comprising lysine or arginine; cysteine or leucine; sodium chloride osmotic agent; aerosol drug delivery; respiratory system disorders; antisecretory and antiinflammatory agents | DISCOVERY LABORATORIES INC. (US) | 2012-07-17 | — | — | US | disclosed |
| US-8212079-B2 | Cocrystallization | APTUIT (WEST LAFAYETTE), LLC (US) | 2012-07-03 | — | — | US | disclosed |
| US-20120116083-A1 | HETEROAROMATIC PYRAZINOYLGUANIDINE SODIUM CHANNEL BLOCKERS | PARION SCIENCES, INC. (US) | 2012-05-10 | — | — | US | disclosed |
| CN-102392061-A | Chemical-enzyme method for preparing D-basic amino acid hydrochloride | UNIV CHONGQING POSTS & TELECOM | 2012-03-28 | — | — | CN | disclosed |
| CN-102392061-A | Chemical-enzyme method for preparing D-basic amino acid hydrochloride | UNIV CHONGQING POSTS & TELECOM | 2012-03-28 | — | — | CN | disclosed |
| US-8124607-B2 | Poly aromatic pyrazinoylguanidine sodium channel blockers | PARION SCIENCES, INC. (US) | 2012-02-28 | — | — | US | disclosed |
| WO-2011155280-A1 | AGENT SUPPRESSING DECREASE IN PRESERVATIVE ABILITY IN AMINO-ACID CONTAINING COMPOSITION | 株式会社資生堂 (JP) | 2011-12-15 | — | — | WO | disclosed |
| US-8058278-B2 | pyrazinoylguanidine derivatives; more potent, more specific, and/or absorbed less rapidly from mucosal surfaces, and/or are less reversible, give a prolonged pharmacodynamic half-life; treating anthrax, chronic bronchitis, cystic fibrosis,chronic obstructive pulmonary disease, emphysema, pneumonia | PARION SCIENCES, INC. (US) | 2011-11-15 | — | — | US | disclosed |
| US-20110257430-A1 | NOVEL COCRYSTALLIZATION | APTUIT (KANSAS CITY), LLC (US) | 2011-10-20 | — | — | US | disclosed |
| US-20110251426-A1 | SCREENING FOR SOLID FORMS BY ULTRASOUND CRYSTALLIZATION AND COCRYSTALLIZATION USING ULTRASOUND | S.S.C.I., INC. (US) | 2011-10-13 | — | — | US | disclosed |
| US-7981898-B2 | Methods of enhancing mucosal hydration and mucosal clearance by treatment with sodium channel blockers and osmolytes | PARION SCIENCES, INC. (US) | 2011-07-19 | — | — | US | disclosed |
| CN-102102197-A | Palladium complex and catalyst-imparting treatment solution using the same | EBARA UDYLITE KK | 2011-06-22 | — | — | CN | disclosed |
| EP-2292585-A1 | Screening for solid forms by ultrasound crystallization and cocrystallization using ultrasound | APTUIT (KANSAS CITY), LLC (US) | 2011-03-09 | — | — | EP | disclosed |
| EP-2258183-A1 | Compounds and uses for the treatment of airway diseases and for the delivery of airway drugs | The University of North Carolina at Chapel Hill (US) | 2010-12-08 | — | — | EP | disclosed |
| EP-2257296-A1 | POLY AROMATIC SODIUM CHANNEL BLOCKERS | Parion Sciences, Inc. (US) | 2010-12-08 | — | — | EP | disclosed |
| CN-101035765-B | Sulfonamide derivatives | HOFFMANN LA ROCHE | 2010-10-13 | — | — | CN | disclosed |
| EP-2211956-A1 | DELIVERING OSMOLYTES BY NASAL CANNULA | Parion Sciences, Inc. (US) | 2010-08-04 | — | — | EP | disclosed |
| US-20100189974-A1 | METAL-LAMINATED POLYIMIDE SUBSTRATE, AND METHOD FOR PRODUCTION THEREOF | EBARA-UDYLITE CO., LTD. (JP) | 2010-07-29 | — | — | US | disclosed |
| CN-101747324-A | Sulfonamide derivatives | HOFFMANN LA ROCHE | 2010-06-23 | — | — | CN | disclosed |
| US-20100150898-A1 | COMPOUNDS AND METHODS FOR THE TREATMENT OF AIRWAY DISEASES AND FOR THE DELIVERY OF AIRWAY DRUGS | BOUCHER JR RICHARD C | 2010-06-17 | — | — | US | disclosed |
| EP-2191718-A1 | Compounds and uses for the treatment of airway diseases and for the delivery of airway drugs | The University of North Carolina at Chapel Hill (US) | 2010-06-02 | — | — | EP | disclosed |
| CN-101688308-A | Metal-laminated polyimide substrate, and method for production thereof | PANASONIC CORP | 2010-03-31 | — | — | CN | disclosed |
| US-20100074881-A1 | MULTIPLE NEBULIZER SYSTEMS | PARION SCIENCES, INC. (US) | 2010-03-25 | — | — | US | disclosed |
| US-20100047458-A1 | PALLADIUM COMPLEX AND CATALYST-IMPARTING TREATMENT SOLUTION USING THE SAME | EBARA-UDYLITE CO., LTD. (JP) | 2010-02-25 | — | — | US | disclosed |
| US-7666395-B2 | Compounds and methods for the treatment of airway diseases and for the delivery of airway drugs | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2010-02-23 | — | — | US | disclosed |
| US-20100029936-A1 | Quinolone Carboxylic Acids, Derivatives Thereof, and Methods of Making and Using Same | BAUSCH+LOMB OPS B.V. (NL) | 2010-02-04 | — | — | US | disclosed |
| WO-2009139948-A1 | POLY AROMATIC SODIUM CHANNEL BLOCKERS | JOHNSON MICHAEL R (US) | 2009-11-19 | — | — | WO | disclosed |
| US-20090281195-A1 | NOVEL COCRYSTALLIZATION | S.S.C.I., INC. (US) | 2009-11-12 | — | — | US | disclosed |
| US-20090214444-A1 | POLY AROMATIC SODIUM CHANNEL BLOCKERS | PARION SCIENCES, INC. (US) | 2009-08-27 | — | — | US | disclosed |
| US-20090176022-A1 | SURFACE MODIFICATION LIQUID FOR PLASTIC AND METHOD OF METALLIZING PLASTIC SURFACE THEREWITH | EBARA-UDYLITE CO., LTD. (JP) | 2009-07-09 | — | — | US | disclosed |
| EP-2063903-A1 | PULMONARY SURFACTANT FORMULATIONS AND METHODS FOR PROMOTING MUCUS CLEARANCE | Discovery Laboratories, Inc. (US) | 2009-06-03 | — | — | EP | disclosed |
| EP-2059239-A2 | ENHANCED MUCOSAL HYDRATION AND MUCOSAL CLEARANCE BY TREATMENT WITH SODIUM CHANNEL BLOCKERS AND OSMOLYTES | Parion Sciences, Inc. (US) | 2009-05-20 | — | — | EP | disclosed |
| EP-2059237-A2 | METHODS OF ENHANCING MUCOSAL HYDRATION AND MUCOSAL CLEARANCE BY TREATMENT WITH SODIUM CHANNEL BLOCKERS AND OSMOLYTES | Parion Sciences, Inc. (US) | 2009-05-20 | — | — | EP | disclosed |
| EP-2006415-A9 | SURFACE MODIFICATION LIQUID FOR PLASTIC AND METHOD OF METALLIZING PLASTIC SURFACE THEREWITH | Ebara-Udylite Co., Ltd. (JP) | 2009-05-20 | — | — | EP | disclosed |
| US-20090104272-A1 | INHALED HYPERTONIC SALINE DELIVERED BY A HEATED NASAL CANNULA | PARION SCIENCES, INC. (US) | 2009-04-23 | — | — | US | disclosed |
| WO-2009049159-A1 | DELIVERING OSMOLYTES BY NASAL CANNULA | PARION SCIENCES, INC. (US) | 2009-04-16 | — | — | WO | disclosed |
| CN-101400823-A | Surface modification liquid for plastic and method for metallizing plastic surface using the same | EBERA UDYLITE CO LTD (JP) | 2009-04-01 | — | — | CN | disclosed |
| US-20090082287-A1 | METHODS OF ENHANCING MUCOSAL HYDRATION AND MUCOSAL CLEARANCE BY TREATMENT WITH SODIUM CHANNEL BLOCKERS AND OSMOLYTES | PARION SCIENCES, INC. (US) | 2009-03-26 | — | — | US | disclosed |
| EP-2006415-A2 | SURFACE MODIFICATION LIQUID FOR PLASTIC AND METHOD OF METALLIZING PLASTIC SURFACE THEREWITH | Ebara-Udylite Co., Ltd. (JP) | 2008-12-24 | — | — | EP | disclosed |
| CN-101326306-A | Palladium complex and catalyst-imparting treatment liquid using the same | EBARA UDYLITE KK (JP) | 2008-12-17 | — | — | CN | disclosed |
| US-7452555-B2 | Cocrystallization | S.S.C.I., INC. (US) | 2008-11-18 | — | — | US | disclosed |
| US-20080199410-A1 | Pulmonary surfactant formulations and methods for promoting mucus clearance | DISCOVERY LABORATORIES, INC. | 2008-08-21 | — | — | US | disclosed |
| EP-1959029-A1 | PALLADIUM COMPLEX AND CATALYST-IMPARTING TREATMENT SOLUTION USING THE SAME | Ebara-Udylite Co., Ltd. (JP) | 2008-08-20 | — | — | EP | disclosed |
| US-20080090841-A1 | METHODS OF ENHANCING MUCOSAL HYDRATION AND MUCOSAL CLEARANCE BY TREATMENT WITH SODIUM CHANNEL BLOCKERS AND OSMOLYTES | PARION SCIENCES, INC. (US) | 2008-04-17 | — | — | US | disclosed |
| WO-2008036293-A1 | PULMONARY SURFACTANT FORMULATIONS AND METHODS FOR PROMOTING MUCUS CLEARANCE | DISCOVERY LABORATORIES, INC. (US) | 2008-03-27 | — | — | WO | disclosed |
| WO-2008031048-A2 | ENHANCED MUCOSAL HYDRATION AND MUCOSAL CLEARANCE BY TREATMENT WITH SODIUM CHANNEL BLOCKERS AND OSMOLYTES | PARION SCIENCES, INC. (US) | 2008-03-13 | — | — | WO | disclosed |
| WO-2008031028-A2 | METHODS OF ENHANCING MUCOSAL HYDRATION AND MUCOSAL CLEARANCE BY TREATMENT WITH SODIUM CHANNEL BLOCKERS AND OSMOLYTES | PARION SCIENCES, INC. (US) | 2008-03-13 | — | — | WO | disclosed |
| US-20070287194-A1 | Screening For Solid Forms By Ultrasound Crystallization And Cocrystallization Using Ultrasound | S.S.C.I., INC | 2007-12-13 | — | — | US | disclosed |
| CN-101035765-A | Sulfonamide derivatives | HOFFMANN LA ROCHE (CH) | 2007-09-12 | — | — | CN | disclosed |
| US-7253158-B2 | Sulfonamides | HOFFMANN-LA ROCHE INC. (US) | 2007-08-07 | — | — | US | disclosed |
| US-7220399-B2 | Alpha or beta emitters attached to fragments in radioimmunotherapy | CENTER FOR MOLECULAR MEDICINE AND IMMUNOLOGY (US) | 2007-05-22 | — | — | US | disclosed |
| US-20070088508-A1 | Cocrystallization methods | APTUIT (WEST LAFAYETTE), LLC | 2007-04-19 | — | — | US | disclosed |
| EP-1768960-A1 | SULFONAMIDE DERIVATIVES | F.HOFFMANN-LA ROCHE AG (CH) | 2007-04-04 | — | — | EP | disclosed |
| US-20060142208-A1 | Compounds and methods for the treatment of airway diseases and for the delivery of airway drugs | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 2006-06-29 | — | — | US | disclosed |
| US-20060014945-A1 | N-((hetero)aryl)-N-(2-oxo-azepan-3-yl)-benzenesulfonamides; useful treating AD or common cancers by blocking the activity of gamma-secretase and reducing/preventing the formation of amyloidogenic Abeta peptides and by blocking the Notch signaling pathways that can interfere with cancer pathogenesis. | F. HOFFMANN-LA ROCHE AG (CH) | 2006-01-19 | — | — | US | disclosed |
| WO-2006005486-A1 | SULFONAMIDE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2006-01-19 | — | — | WO | disclosed |
| US-6926911-B1 | Compounds and methods for the treatment of airway diseases and for the delivery of airway drugs | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2005-08-09 | — | — | US | disclosed |
| US-20050106264-A1 | Compounds and methods for the treatment of airway diseases and for the delivery of airway drugs | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2005-05-19 | — | — | US | disclosed |
| US-20040180001-A1 | Alpha or beta emitters attached to fragments in radioimmunotherapy | CENTER FOR MOLECULAR MEDICINE AND IMMUNOLOGY | 2004-09-16 | — | — | US | disclosed |
| US-6667024-B1 | Kit comprising molecule with radioisotope binding site linked to antigen-binding fragment of antibody that specifically binds to tumor associated antigen, and metal chelator and basic amino acid or peptide clearing agents | CENTER FOR MOLECULAR MEDICINE AND IMMUNOLOGY | 2003-12-23 | — | — | US | disclosed |
| EP-0981318-B1 | COMPOSITION FOR TREATING HAIR | OREAL (FR) | 2003-07-09 | — | — | EP | disclosed |
| EP-0855398-B1 | SESQUITERPENE DERIVATIVES HAVING ANTIVIRAL ACTIVITY | SHIONOGI & CO (JP) | 2003-04-16 | — | — | EP | disclosed |
| US-20020099023-A1 | Compounds and methods for the treatment of airway diseases and for the delivery of airway drugs | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2002-07-25 | — | — | US | disclosed |
| EP-1187637-A2 | ALPHA OR BETA EMITTERS ATTACHED TO FRAGMENTS IN RADIOIMMUNOTHERAPY | CENTER FOR MOLECULAR MEDICINE AND IMMUNOLOGY (US) | 2002-03-20 | — | — | EP | disclosed |
| WO-2000074729-A2 | ALPHA OR BETA EMITTERS TO FRAGMENTS IN RADIOIMMUNOTHERAPY | CENTER FOR MOLECULAR MEDICINE AND IMMUNOLOGY (US) | 2000-12-14 | — | — | WO | disclosed |
| US-5876984-A | OBTAINED BY CULTURING MICROORGANISM OF STACHYBOTRYS GENUS | SHIONOGI & CO., LTD (JP) | 1999-03-02 | — | — | US | disclosed |
| CN-1202897-A | Sesquiterpene derivatives having antiviral activity | SHIONOGI & CO (JP) | 1998-12-23 | — | — | CN | disclosed |
| EP-0855398-A1 | SESQUITERPENE DERIVATIVES HAVING ANTIVIRAL ACTIVITY | SHIONOGI & CO., LTD. (JP) | 1998-07-29 | — | — | EP | disclosed |
| US-5723321-A | MICROORGANISMS | TANABE SEIYAKU CO., LTD. (JP) | 1998-03-03 | — | — | US | disclosed |
| US-5608076-A | Method of preparing amionoakylhydantoins and aminoalkyl-alpha-amino acids | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1997-03-04 | — | — | US | disclosed |
| EP-0719865-A1 | Process for preparing D-lysine | TANABE SEIYAKU CO., LTD. (JP) | 1996-07-03 | — | — | EP | disclosed |
| EP-0127154-B1 | PHARMACEUTICAL PEPTIDES, PREPARATION, USE AND INTERMEDIATES | THE WELLCOME FOUNDATION LIMITED (GB) | 1990-10-03 | — | — | EP | disclosed |
| US-4540682-A | ANALGESICS | BURROUGHS WELLCOME CO. (US) | 1985-09-10 | — | — | US | disclosed |
| EP-0057092-B1 | PROCESS FOR RACEMIZING AN OPTICALLY ACTIVE ALPHA-AMINO ACID OR A SALT THEREOF | Tanabe Seiyaku Co., Ltd. (JP) | 1985-05-02 | — | — | EP | disclosed |
| EP-0127154-A2 | Pharmaceutical peptides, preparation, use and intermediates | THE WELLCOME FOUNDATION LIMITED (GB) | 1984-12-05 | — | — | EP | disclosed |
| US-4401820-A | IN THE PRESENCE OF AN ACYCLIC ACID AND AN ALDEHYDE; STABILITY | TANABE SEIYAKU CO., LTD. (JP) | 1983-08-30 | — | — | US | disclosed |
| EP-0010297-B1 | DERIVATIVES OF POLYENE MACROLIDE ANTIBIOTICS CONTAINING AN AMINO SUGAR MOIETY, PROCESS FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SCHERING CORPORATION (US) | 1983-04-13 | — | — | EP | disclosed |
| EP-0057092-A1 | Process for racemizing an optically active alpha-amino acid or a salt thereof | Tanabe Seiyaku Co., Ltd. (JP) | 1982-08-04 | — | — | EP | disclosed |
| US-4272525-A | FUNGICIDES | SCHERING CORPORATION (US) | 1981-06-09 | — | — | US | disclosed |
| EP-0010297-A1 | Derivatives of polyene macrolide antibiotics containing an amino sugar moiety, process for the preparation thereof, and pharmaceutical compositions containing them | SCHERING CORPORATION (US) | 1980-04-30 | — | — | EP | disclosed |
| EP-0010297-A1 | Derivatives of polyene macrolide antibiotics containing an amino sugar moiety, process for the preparation thereof, and pharmaceutical compositions containing them | SCHERING CORPORATION (US) | 1980-04-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (50 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160193122-A1 | POLYUREA OR POLYURETHANE CAPSULES | PARG, MUS81, CCNY | GSR 3007/4885ARG2 3953/4885ARG1 3052/4885 |
| US-20100029936-A1 | Quinolone Carboxylic Acids, Derivatives Thereof, and Methods of Making and Using Same | NQO2, QARS1, QPCT | GSR 2096/4885ARG2 1219/4885ARG1 1331/4885 |
| US-20250000761-A1 | BIODEGRADABLE MICROCAPSULES | SGMS2, SRM, SGMS1 | GSR 2237/4885ARG2 290/4885ARG1 242/4885 |
| US-20180042825-A1 | MICROCAPSULE COMPOSITIONS WITH HIGH PERFORMANCE | UMPS, AUP1, PFAS | GSR 2823/4885ARG2 2511/4885ARG1 3687/4885 |
| US-20190231658-A1 | STABLE MICROCAPSULE COMPOSITIONS | LIPA, PNLIP, PHOSPHO1 | GSR 3217/4885ARG2 3952/4885ARG1 4207/4885 |
| US-20250115561-A1 | BIPHENYL-SUBSTITUTED EPITHELIAL SODIUM CHANNEL BLOCKING COMPOUNDS | CFTR, SCNN1B, SCNN1G | GSR 3616/4885ARG2 4762/4885ARG1 4648/4885 |
| US-20180272308-A1 | HYBRID CAPSULES | UFM1, SMARCA1, PUF60 | GSR 2544/4885ARG2 3438/4885ARG1 1546/4885 |
| US-20180104241-A1 | CHEMICALLY AND METABOLICALLY STABLE DIPEPTIDE POSSESSING POTENT SODIUM CHANNEL BLOCKER ACTIVITY | CACNA1B, SCN1B, SCN2B | GSR 953/4885ARG2 1073/4885ARG1 1323/4885 |
| US-20100047458-A1 | PALLADIUM COMPLEX AND CATALYST-IMPARTING TREATMENT SOLUTION USING THE SAME | ARGLU1, PADI1, PADI2 | GSR 2773/4885ARG2 457/4885ARG1 32/4885 |
| US-20140170244-A1 | 3,5-DIAMINO-6-CHLORO-N-(N-(4-PHENYLBUTYL)CARBAMIMIDOYL) PYRAZINE-2- CARBOXAMIDE COMPOUNDS | CFTR, SCNN1B, SCN5A | GSR 3536/4885ARG2 738/4885ARG1 746/4885 |
| US-20170216166-A1 | CAPSULES CONTAINING POLYVINYL ALCOHOL | ADH1A, ADH5, ADH1C | GSR 4419/4885ARG2 4746/4885ARG1 4366/4885 |
| US-20160194278-A1 | DITHIOL MUCOLYTIC AGENTS | MUC1, DNASE1, MMP8 | GSR 315/4885ARG2 3082/4885ARG1 3226/4885 |
| US-20090082287-A1 | METHODS OF ENHANCING MUCOSAL HYDRATION AND MUCOSAL CLEARANCE BY TREATMENT WITH SODIUM CHANNEL BLOCKERS AND OSMOLYTES | SCNN1B, SLC10A2, SCNN1A | GSR 1653/4885ARG2 2394/4885ARG1 2235/4885 |
| US-12048755-B2 | Microcapsule compositions prepared from polysaccharides | ALG1, MGAM, PNLIP | GSR 3844/4885ARG2 3875/4885ARG1 2975/4885 |
| US-20150307530-A1 | NOVEL MUCOLYTIC AGENTS | MUC1, MMP8, MMP7 | GSR 678/4885ARG2 1641/4885ARG1 1498/4885 |
| US-20140142118-A1 | CHEMICALLY AND METABOLICALLY STABLE DIPEPTIDE POSSESSING POTENT SODIUM CHANNEL BLOCKER ACTIVITY | CACNA1B, SCN1B, KCNB1 | GSR 1326/4885ARG2 1167/4885ARG1 1581/4885 |
| US-20140107133-A1 | 3,5-DIAMINO-6-CHLORO-N-(N-(4-(4-(2-(HEXYL(2,3,4,5,6-PENTAHYDROXYHEXYL)AMINO)ETHOXY)PHENYL)BUTYL)CARBAMIMIDOYL)PYRAZINE-2-CARBOXAMIDE | CFTR, ELANE, IL5 | GSR 3254/4885ARG2 189/4885ARG1 317/4885 |
| US-20230051314-A1 | BIODEGRADABLE MICROCAPSULES | LIPA, MLEC, LRBA | GSR 3510/4885ARG2 1806/4885ARG1 1555/4885 |
| US-20060014945-A1 | N-((hetero)aryl)-N-(2-oxo-azepan-3-yl)-benzenesulfonamides; useful treating AD or common cancers by blocking the activity of gamma-secretase and reducing/preventing the formation of amyloidogenic Abeta peptides and by blocking the Notch signaling pathways that can interfere with cancer pathogenesis. | BACE1, APP, BACE2 | GSR 1998/4885ARG2 1316/4885ARG1 598/4885 |
| US-12409113-B2 | Polyurea or polyurethane capsules | PUF60, PARG, UMPS | GSR 3123/4885ARG2 3410/4885ARG1 2298/4885 |
| US-20170281620-A1 | CHEMICALLY AND METABOLICALLY STABLE DIPEPTIDE POSSESSING POTENT SODIUM CHANNEL BLOCKER ACTIVITY | CACNA1B, SCN1B, KCNB1 | GSR 1326/4885ARG2 1167/4885ARG1 1581/4885 |
| US-12357547-B2 | Compositions containing microcapsules | COPE, SAAL1, AUP1 | GSR 4844/4885ARG2 4054/4885ARG1 2490/4885 |
| US-20180064615-A1 | RELOADABLE MICROCAPSULES | MLEC, LIPA, CHMP4B | GSR 3489/4885ARG2 2088/4885ARG1 2089/4885 |
| US-20130337023-A1 | POLYUREA CAPSULES PREPARED WITH ALIPHATIC ISOCYANATES AND AMINES | PUF60, ACMSD, ALKBH1 | GSR 2741/4885ARG2 512/4885ARG1 199/4885 |
| US-10555879-B2 | Polyurea capsule compositions | PUF60, UMPS, PCBP1 | GSR 3806/4885ARG2 2121/4885ARG1 2208/4885 |
| US-10085925-B2 | Polyurea capsule compositions | PUF60, UMPS, PCBP1 | GSR 3806/4885ARG2 2121/4885ARG1 2208/4885 |
| US-20160016982-A1 | CRYSTALLIZATION METHOD AND BIOAVAILABILITY | ABCG2, GYS2, PYGL | GSR 2522/4885ARG2 4444/4885ARG1 4237/4885 |
| US-20200046616-A1 | POLYUREA OR POLYURETHANE CAPSULES | PUF60, PARG, UMPS | GSR 3123/4885ARG2 3410/4885ARG1 2298/4885 |
| US-20150299142-A1 | 3,5-DIAMINO-6-CHLORO-N-(4-PHENYLBUTYL)CARBAMIMIDOYL) PYRAZINE-2-CARBOXAMIDE COMPOUNDS | CFTR, SCNN1B, SCN5A | GSR 3559/4885ARG2 733/4885ARG1 688/4885 |
| US-20180346648-A1 | BRANCHED POLYETHYLENEIMINE MICROCAPSULES | PCBP1, PRUNE1, MC5R | GSR 3201/4885ARG2 2799/4885ARG1 3972/4885 |
| US-20220071864-A1 | HYDROXYETHYL CELLULOSE MICROCAPSULES | MGAM, LIPA, MLEC | GSR 3743/4885ARG2 2687/4885ARG1 2166/4885 |
| US-20160289262-A1 | BILE ACID DERIVATIVES AS FXR/TGR5 AGONISTS AND METHODS OF USE THEREOF | GPBAR1, NR1H4, SLC10A1 | GSR 933/4885ARG2 4538/4885ARG1 4145/4885 |
| US-20210024471-A1 | 3,5-DIAMINO-6-CHLORO-N-(N-(4-(4-(2-(HEXYL(2,3,4,5,6-PENTAHYDROXYHEXYL)AMINO)ETHOXY)PHENYL)BUTYL)CARBAMIMIDOYL)PYRAZINE-2-CARBOXAMIDE | CFTR, ELANE, IL5 | GSR 3254/4885ARG2 189/4885ARG1 317/4885 |
| US-11540985-B2 | Stable microcapsule compositions | LIPA, AUP1, PHOSPHO1 | GSR 3196/4885ARG2 3686/4885ARG1 4091/4885 |
| US-10092486-B2 | Polyurea or polyurethane capsules | PARG, MUS81, CCNY | GSR 3007/4885ARG2 3953/4885ARG1 3052/4885 |
| US-20150056305-A1 | DITHIOL MUCOLYTIC AGENTS | MUC1, DNASE1, MMP8 | GSR 315/4885ARG2 3082/4885ARG1 3226/4885 |
| US-20220008299-A1 | Compositions Containing Microcapsules Coated with Deposition Proteins | AUP1, CAPG, TTR | GSR 4804/4885ARG2 4330/4885ARG1 3527/4885 |
| US-10434045-B2 | Polyurea or polyurethane capsules | PUF60, UMPS, PARG | GSR 2790/4885ARG2 3569/4885ARG1 2296/4885 |
| US-20220175636-A1 | CONSUMER PRODUCT WITH CONTROLLED RELEASE, BIODEGRADABLE CORE-SHELL MICROCAPSULE COMPOSITIONS | LIPA, LIPE, CAPG | GSR 3405/4885ARG2 2795/4885ARG1 2732/4885 |
| US-20150099764-A1 | DENDRIMER LIKE AMINO AMIDES POSSESSING SODIUM CHANNEL BLOCKER ACTIVITY FOR THE TREATMENT OF DRY EYE AND OTHER MUCOSAL DISEASES | SCNN1B, SCNN1A, SCNN1G | GSR 2970/4885ARG2 1148/4885ARG1 568/4885 |
| US-20150290189-A1 | CHEMICALLY AND METABOLICALLY STABLE DIPEPTIDE POSSESSING POTENT SODIUM CHANNEL BLOCKER ACTIVITY | CACNA1B, SCN1B, KCNB1 | GSR 1326/4885ARG2 1167/4885ARG1 1581/4885 |
| US-20190159979-A1 | RELOADABLE MICROCAPSULES | MLEC, LIPA, CHMP4B | GSR 3489/4885ARG2 2088/4885ARG1 2089/4885 |
| US-10695272-B2 | Compositions containing microcapsules coated with deposition proteins | SAAL1, AUP1, FABP5 | GSR 4865/4885ARG2 4336/4885ARG1 2485/4885 |
| US-20230172820-A1 | Compositions Containing Microcapsules | COPE, SAAL1, AUP1 | GSR 4844/4885ARG2 4054/4885ARG1 2490/4885 |
| US-12558297-B2 | Consumer product with controlled release, biodegradable core-shell microcapsule compositions | LCT, CUTA, LIPE | GSR 2069/4885ARG2 1251/4885ARG1 655/4885 |
| US-12419815-B2 | Microcapsule compositions stabilized with viscosity control agents | ACR, ALG1, MLEC | GSR 3982/4885ARG2 3677/4885ARG1 2955/4885 |
| US-20130035315-A1 | CRYSTALLIZATION METHOD AND BIOAVAILABILITY | ABCG2, GYS2, PYGL | GSR 2522/4885ARG2 4444/4885ARG1 4237/4885 |
| US-10106551-B2 | Monothiol mucolytic agents | MUC1, HRH2, MAN2A1 | GSR 723/4885ARG2 967/4885ARG1 736/4885 |
| US-12303855-B2 | Stable polyurea microcapsule compositions for aldehyde fragrances | PUF60, MSI2, EFTUD2 | GSR 3885/4885ARG2 4335/4885ARG1 4604/4885 |
| US-10233158-B2 | Arylalkyl- and aryloxyalkyl-substituted epithelial sodium channel blocking compounds | CFTR, SCNN1B, SCNN1A | GSR 3418/4885ARG2 2399/4885ARG1 1798/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.