Known targets — ChEMBL curated mechanism
PPARDPTGS1PTGS2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Lysine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 2/20 | 0.95 |
| ▸ | ARG2 | P78540 | 4/20 | 0.61 |
| ▸ | ARG1 | P05089 | 3/20 | 0.57 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.56 |
| ▸ | NOS2 | P35228 | 4/20 | 0.53 |
| ▸ | NOS1 | P29475 | 3/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | NOS3 | P29474 | 2/20 | 0.50 |
| ▸ | GGT1 | P19440 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | GRM8 | O00222 | 1/20 | 0.50 |
| ▸ | GRM6 | O15303 | 1/20 | 0.50 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.50 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.50 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.50 |
| ▸ | GRM5 | P41594 | 1/20 | 0.50 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.50 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lysine SCHEMBL875015 | 1.00 | GSR (0.95) | GSRARG2ARG1RNPEPNOS2 | |
| Lysine SCHEMBL706905 | 1.00 | GSR (0.95) | GSRARG2ARG1RNPEPNOS2 | |
| Lysine SCHEMBL16893975 | 1.00 | GSR (0.95) | GSRARG2ARG1RNPEPNOS2 | |
| Lysine SCHEMBL8029574 | 1.00 | GSR (0.95) | GSRARG2ARG1RNPEPNOS2 | |
| Lysine SCHEMBL1191963 | 1.00 | GSR (0.95) | GSRARG2ARG1RNPEPNOS2 | |
| Lysine SCHEMBL10582149 | 1.00 | GSR (0.95) | GSRARG2ARG1RNPEPNOS2 | |
| Lysine SCHEMBL9762590 | 1.00 | GSR (0.95) | GSRARG2ARG1RNPEPNOS2 | |
| Lysine SCHEMBL41760 | 1.00 | GSR (0.95) | GSRARG2ARG1RNPEPNOS2 | |
| Lysine SCHEMBL2478576 | 1.00 | GSR (0.95) | GSRARG2ARG1RNPEPNOS2 | |
| Lysine SCHEMBL30928253 | 1.00 | GSR (0.95) | GSRARG2ARG1RNPEPNOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 23313 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122081234-A | Low-serum MSB1 suspension medium and chicken infectious anemia virus inactivated vaccine | — | 2026-05-26 | — | — | CN | claimed |
| CN-121379932-B | Culture medium for high-density serum-free suspension culture of BHK-21 cells and application thereof | Zhongsheng tianxinhe (Wuxi) Biotechnology Co.,Ltd. (CN) | 2026-05-26 | — | — | CN | claimed |
| WO-2026106819-A1 | MICROCARRIERS WITH IMPROVED REHYDRATION | CORNING INCORPORATED (US) | 2026-05-21 | — | — | WO | claimed |
| CN-122056386-A | Moisture absorption resistant slow release microcapsule powder and preparation method and application thereof | 大连医诺生物股份有限公司 | 2026-05-19 | — | — | CN | claimed |
| CN-121674377-B | Preparation method of human blood coagulation factor IX stock solution | 深圳市卫光生物制品股份有限公司 | 2026-05-19 | — | — | CN | claimed |
| CN-122030518-A | Parent feed for procambarus clarkia and preparation method thereof | 湖南省水产研究所(湖南省水产原种场) | 2026-05-15 | — | — | CN | claimed |
| CN-122030612-A | Shear-resistant slow-release microcapsule powder and preparation method and application thereof | 大连医诺生物股份有限公司 | 2026-05-15 | — | — | CN | claimed |
| CN-122038067-A | Solid beer flavor effervescent tablet and preparation method thereof | 技源健康科技(江苏)有限公司 | 2026-05-15 | — | — | CN | claimed |
| CN-122004358-A | Microelement composite additive for improving reproductive performance of pets | 北京中农劲腾生物制药股份有限公司 | 2026-05-12 | — | — | CN | claimed |
| CN-122004362-A | Tryptophan-added bullfrog feed composition and application thereof | 集美大学 | 2026-05-12 | — | — | CN | claimed |
| US-4126628-A | BASIC CATALYST | CANADIAN PATENTS AND DEVELOPMENT LIMITED (CA) | 1978-11-21 | — | — | US | claimed |
| US-4100293-A | Treatment of hepatic disorders with therapeutic compositions comprising keto analogs of essential amino acids | THE JOHNS HOPKINS UNIVERSITY (US) | 1978-07-11 | — | — | US | claimed |
| US-4100161-A | Promotion of protein synthesis and suppression of urea formation in the body by keto analogs of essential amino acids | THE JOHNS HOPKINS UNIVERSITY (US) | 1978-07-11 | — | — | US | claimed |
| US-4100160-A | Therapeutic compositions comprising alpha-hydroxy analogs of essential amino acids and their administration to humans for promotion of protein synthesis and suppression of urea formation | THE JOHNS HOPKINS UNIVERSITY (US) | 1978-07-11 | — | — | US | claimed |
| US-4035513-A | COSMETICS | SHISEIDO CO., LTD. (JA) | 1977-07-12 | — | — | US | claimed |
| US-3995065-A | WHEAT GERM AND GLUTEN, CASEIN, SOY PROTEIN ISOLATE, LACTALBUMIN, EGG WHITE SOLIDS, L-LYSINE HYDROCHLORIDE | INTERNATIONAL TELEPHONE AND TELEGRAPH CORPORATION (US) | 1976-11-30 | — | — | US | claimed |
| US-3987206-A | WHEY, SOYBEAN PROTEIN, CASEIN, LYSINE HYDROCHLORIDE | INTERNATIONAL TELEPHONE AND TELEGRAPH CORPORATION (US) | 1976-10-19 | — | — | US | claimed |
| US-3970750-A | LYSINE HYDROCHLORIDE | SANDOZ, INC. (US) | 1976-07-20 | — | — | US | claimed |
| US-3962480-A | Bread including nutritional amounts of magnesium | WOLF SIDNEY K | 1976-06-08 | — | — | US | claimed |
| US-3931308-A | Process for conversion of lysine dihydrochloride to lysine monohydrochloride | ALLIED CHEMICAL CORPORATION (US) | 1976-01-06 | — | — | US | claimed |