Known targets — ChEMBL curated mechanism
PPARDPTGS1PTGS2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Lysine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 2/20 | 0.95 |
| ▸ | ARG2 | P78540 | 4/20 | 0.61 |
| ▸ | ARG1 | P05089 | 3/20 | 0.57 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.56 |
| ▸ | NOS2 | P35228 | 4/20 | 0.53 |
| ▸ | NOS1 | P29475 | 3/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | NOS3 | P29474 | 2/20 | 0.50 |
| ▸ | GGT1 | P19440 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | GRM8 | O00222 | 1/20 | 0.50 |
| ▸ | GRM6 | O15303 | 1/20 | 0.50 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.50 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.50 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.50 |
| ▸ | GRM5 | P41594 | 1/20 | 0.50 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.50 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lysine SCHEMBL706905 | 1.00 | GSR (0.95) | GSRARG2ARG1RNPEPNOS2 | |
| Lysine SCHEMBL16893975 | 1.00 | GSR (0.95) | GSRARG2ARG1RNPEPNOS2 | |
| Lysine SCHEMBL8029574 | 1.00 | GSR (0.95) | GSRARG2ARG1RNPEPNOS2 | |
| Lysine SCHEMBL41761 | 1.00 | GSR (0.95) | GSRARG2ARG1RNPEPNOS2 | |
| Lysine SCHEMBL1191963 | 1.00 | GSR (0.95) | GSRARG2ARG1RNPEPNOS2 | |
| Lysine SCHEMBL10582149 | 1.00 | GSR (0.95) | GSRARG2ARG1RNPEPNOS2 | |
| Lysine SCHEMBL9762590 | 1.00 | GSR (0.95) | GSRARG2ARG1RNPEPNOS2 | |
| Lysine SCHEMBL41760 | 1.00 | GSR (0.95) | GSRARG2ARG1RNPEPNOS2 | |
| Lysine SCHEMBL2478576 | 1.00 | GSR (0.95) | GSRARG2ARG1RNPEPNOS2 | |
| Lysine SCHEMBL30928253 | 1.00 | GSR (0.95) | GSRARG2ARG1RNPEPNOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 648 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122011360-A | Method for preparing two-arm PEG modifier | 吉林省金派格药业有限责任公司 | 2026-05-12 | — | — | CN | claimed |
| US-20250057865-A1 | ANTIVIRAL SUPPLEMENT FORMULATIONS FOR HERPESVIRUS INFECTIONS | Vymedic, Inc. | 2025-02-20 | — | — | US | claimed |
| WO-2025038636-A1 | ANTIVIRAL SUPPLEMENT FORMULATIONS FOR HERPESVIRUS INFECTIONS | Vymedic, Inc. (US) | 2025-02-20 | — | — | WO | claimed |
| US-12178874-B2 | Aflibercept formulations containing a lysine salt as tonicifying agent and uses thereof | JUST-EVOTEC BIOLOGICS, INC. (US) | 2024-12-31 | — | — | US | claimed |
| CN-118955331-A | Preparation method of amino acid derivative with side chain amino protection | 四川鸿日医药科技有限公司 | 2024-11-15 | — | — | CN | claimed |
| US-12024592-B2 | Hyperbranched polylysine powder with low polydispersity index and production method thereof | ZHEJIANG UNIVERSITY (CN) | 2024-07-02 | — | — | US | claimed |
| US-20240075048-A1 | ANTIVIRAL SUPPLEMENT FORMULATIONS | VYMEDIC INC. | 2024-03-07 | — | — | US | claimed |
| US-20240018303-A1 | HYPERBRANCHED POLYLYSINE POWDER WITH LOW POLYDISPERSITY INDEX AND PRODUCTION METHOD THEREOF | ZHEJIANG UNIVERSITY (CN) | 2024-01-18 | — | — | US | claimed |
| US-11826377-B2 | Antiviral supplement formulations | VYMEDIC, LLC (US) | 2023-11-28 | — | — | US | claimed |
| WO-2023163559-A1 | STEM CELL CULTURE METHOD USING SERUM-FREE MEDIUM | 주식회사 강스템바이오텍 | 2023-08-31 | — | — | WO | claimed |
| EP-0752843-A1 | ARTIFICIAL TANNING COMPOSITIONS HAVING IMPROVED COLOR DEVELOPMENT | THE PROCTER & GAMBLE COMPANY (US) | 1997-01-15 | — | — | EP | claimed |
| US-5589277-A | INK JET PRINTING, AQUEOUS INKS, FAST DRYING | XEROX CORPORATION (US) | 1996-12-31 | — | — | US | claimed |
| US-5514437-A | DIHYDROXYACETONE; METABISULFITE, SULFITE AND/OR HYDROGEN SULFITE SALT; TOPICAL CARRIER; PROVIDING ARTIFICIAL TAN TO HUMAN SKIN AND OPTIONALLY PROTECTING SKIN FROM HARMFUL EFFECTS OF ULTRAVIOLET RADIATION BY USE THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 1996-05-07 | — | — | US | claimed |
| WO-1996000279-A1 | STRUCTURED DETERGENT PASTES AND A METHOD FOR MANUFACTURING DETERGENT PARTICLES FROM SUCH PASTES | THE PROCTER & GAMBLE COMPANY (US) | 1996-01-04 | — | — | WO | claimed |
| EP-0688862-A1 | Structured detergent pastes and a method for manufacturing detergent particles from such pastes | THE PROCTER & GAMBLE COMPANY (US) | 1995-12-27 | — | — | EP | claimed |
| WO-1995026178-A1 | ARTIFICAL TANNING COMPOSITIONS HAVING IMPROVED STABILITY | THE PROCTER & GAMBLE COMPANY (US) | 1995-10-05 | — | — | WO | claimed |
| WO-1995026179-A1 | ARTIFICIAL TANNING COMPOSITIONS HAVING IMPROVED COLOR DEVELOPMENT | THE PROCTER & GAMBLE COMPANY (US) | 1995-10-05 | — | — | WO | claimed |
| EP-0667246-A1 | Recording sheets containing amino acids, hydroxy acids, and polycarboxyl compounds | XEROX CORPORATION (US) | 1995-08-16 | — | — | EP | claimed |
| US-4044125-A | GLUTAMIC ACID, GLYCINE, ASPARTIC ACID, OR ALANINE HYDROCHLORIDE, LYSINE DIHYDROCHLORIDE | ELI LILLY AND COMPANY (US) | 1977-08-23 | — | — | US | claimed |
| US-3931308-A | Process for conversion of lysine dihydrochloride to lysine monohydrochloride | ALLIED CHEMICAL CORPORATION (US) | 1976-01-06 | — | — | US | claimed |