SCHEMBL417618

SCHEMBL417618

CC(C)(C)OC(=O)CN(CC(=O)ON1C(=O)CCC1=O)CC(=O)OC(C)(C)C

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
NR1D1 P20393 5/20 0.32
NR1H3 Q13133 1/20 0.31
PLA2G10 O15496 1/20 0.31
PLA2G5 P39877 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3861378 0.87 MGLL (0.32)
SCHEMBL4815974 0.83 MT-CO2 (0.33)
SCHEMBL8740492 0.82 STING1 (0.34) PLA2G10PLA2G5
SCHEMBL4595993 0.82 CTSD (0.32)
SCHEMBL6433493 0.81
SCHEMBL2578067 0.81 CA14 (0.33)
SCHEMBL13747089 0.81 MT-CO2 (0.34)
SCHEMBL13012119 0.80 OPRK1 (0.33)
SCHEMBL16020547 0.80 OPRK1 (0.36)
SCHEMBL24276652 0.79 DDB1 (0.34) PLA2G10PLA2G5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130012432-A1 Peptides for Treatment of Obesity NOVO NORDISK A/S (DK) 2013-01-10 US disclosed
US-20130012432-A1 Peptides for Treatment of Obesity NOVO NORDISK A/S (DK) 2013-01-10 US disclosed
US-20130012432-A1 Peptides for Treatment of Obesity NOVO NORDISK A/S (DK) 2013-01-10 US disclosed
EP-2539364-A1 PEPTIDES FOR TREATMENT OF OBESITY Novo Nordisk A/S (DK) 2013-01-02 EP disclosed
US-20120021973-A1 Peptides for Treatment of Obesity NOVO NORDISK A/S (DK) 2012-01-26 US disclosed
US-20120021973-A1 Peptides for Treatment of Obesity NOVO NORDISK A/S (DK) 2012-01-26 US disclosed
US-20120021973-A1 Peptides for Treatment of Obesity NOVO NORDISK A/S (DK) 2012-01-26 US disclosed
EP-2370104-A1 PEPTIDES FOR TREATMENT OF OBESITY Novo Nordisk A/S (DK) 2011-10-05 EP disclosed
WO-2011104378-A1 PEPTIDES FOR TREATMENT OF OBESITY NOVO NORDISK A/S (DK) 2011-09-01 WO disclosed
WO-2011104378-A1 PEPTIDES FOR TREATMENT OF OBESITY NOVO NORDISK A/S (DK) 2011-09-01 WO disclosed
US-20100173835-A1 Peptides for Treatment of Obesity NOVO NORDISK A/S (DK) 2010-07-08 US disclosed
US-20100173835-A1 Peptides for Treatment of Obesity NOVO NORDISK A/S (DK) 2010-07-08 US disclosed
US-20100173835-A1 Peptides for Treatment of Obesity NOVO NORDISK A/S (DK) 2010-07-08 US disclosed
WO-2010060901-A1 PEPTIDES FOR TREATMENT OF OBESITY NOVO NORDISK A/S (DK) 2010-06-03 WO disclosed
WO-2010060901-A1 PEPTIDES FOR TREATMENT OF OBESITY NOVO NORDISK A/S (DK) 2010-06-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120021973-A1 Peptides for Treatment of Obesity MC4R, GIPR, MC3R NR1D1 806/4885NR1H3 654/4885PLA2G10 1958/4885
US-20100173835-A1 Peptides for Treatment of Obesity MC4R, GIPR, MC3R NR1D1 806/4885NR1H3 654/4885PLA2G10 1958/4885
US-20130012432-A1 Peptides for Treatment of Obesity MC4R, GIPR, MC3R NR1D1 806/4885NR1H3 654/4885PLA2G10 1958/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.