Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.50 |
| ▸ | HTR3B | O95264 | 1/20 | 0.50 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.50 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.50 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.50 |
| ▸ | HTR3A | P46098 | 1/20 | 0.50 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.50 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7171272 | 0.84 | NOTUM (0.53) | NOTUML3MBTL1TSHRRAB9AHTR3E | |
| SCHEMBL30488374 | 0.82 | NOTUM (0.47) | NOTUML3MBTL1TSHRRAB9AHTR3E | |
| SCHEMBL1173678 | 0.81 | NOTUM (0.65) | NOTUML3MBTL1TSHRRAB9AHTR3E | |
| SCHEMBL30711215 | 0.81 | NOTUM (0.65) | NOTUML3MBTL1TSHRRAB9AHTR3E | |
| SCHEMBL4467291 | 0.79 | NOTUM (0.61) | NOTUML3MBTL1TSHRRAB9AHTR3E | |
| SCHEMBL30109103 | 0.78 | NOTUM (0.61) | NOTUML3MBTL1TSHRRAB9AHTR3E | |
| SCHEMBL600415 | 0.78 | NOTUM (0.61) | NOTUML3MBTL1TSHRRAB9AHTR3E | |
| SCHEMBL18990344 | 0.77 | NOTUM (0.59) | NOTUML3MBTL1TSHRRAB9AHTR3E | |
| SCHEMBL18990269 | 0.77 | NOTUM (0.59) | NOTUML3MBTL1TSHRRAB9AHTR3E | |
| SCHEMBL691666 | 0.77 | NOTUM (0.59) | NOTUML3MBTL1TSHRRAB9AHTR3E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7632956-B2 | Fragrance ingredients, applications, compositions and methods | GIVAUDAN SA (CH) | 2009-12-15 | — | — | US | claimed |
| US-20090036690-A1 | ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2009-02-05 | — | — | US | claimed |
| EP-1799797-B1 | ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2008-05-14 | — | — | EP | claimed |
| EP-1799797-A1 | ORGANIC COMPOUNDS | Givaudan SA (CH) | 2007-06-27 | — | — | EP | claimed |
| WO-2006039822-A1 | ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2006-04-20 | — | — | WO | claimed |
| JP-2002540192-A | — | — | 2002-11-26 | — | — | JP | claimed |
| EP-1165511-A2 | METHOD OF PRODUCING HETEROCYCLIC CARBAMATES FROM AZA-HETEROCYCLIC COMPOUNDS AND CARBON DIOXIDE | GÖDECKE GMBH (DE) | 2002-01-02 | — | — | EP | claimed |
| WO-2000058286-A2 | METHOD OF PRODUCING HETEROCYCLIC CARBAMATES FROM AZA-HETEROCYCLIC COMPOUNDS AND CARBON DIOXIDE | Gödecke GmbH (DE) | 2000-10-05 | — | — | WO | claimed |
| CN-108530335-B | Indole compound and preparation method and application thereof | 华南农业大学 | 2021-08-31 | — | — | CN | disclosed |
| CN-108530335-A | A kind of Benzazole compounds and its preparation method and application | 华南农业大学 | 2018-09-14 | — | — | CN | disclosed |
| US-7632956-B2 | Fragrance ingredients, applications, compositions and methods | GIVAUDAN SA (CH) | 2009-12-15 | — | — | US | disclosed |
| US-7632956-B2 | Fragrance ingredients, applications, compositions and methods | GIVAUDAN SA (CH) | 2009-12-15 | — | — | US | disclosed |
| US-7632956-B2 | Fragrance ingredients, applications, compositions and methods | GIVAUDAN SA (CH) | 2009-12-15 | — | — | US | disclosed |
| CN-101374842-A | Azepinoindole derivatives as pharmaceutical agents | EXELIXIS INC (US) | 2009-02-25 | — | — | CN | disclosed |
| EP-1799797-B1 | ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2008-05-14 | — | — | EP | disclosed |
| EP-1799797-A1 | ORGANIC COMPOUNDS | Givaudan SA (CH) | 2007-06-27 | — | — | EP | disclosed |
| WO-2006039822-A1 | ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2006-04-20 | — | — | WO | disclosed |
| US-6566533-B1 | Reacting aza-heterocyclic compounds (indoles and carbazoles) with alkyl- or aryl-halides in the presence of carbon dioxide and alkali carbonate | WARNER-LAMBERT COMPANY LLC | 2003-05-20 | — | — | US | disclosed |
| EP-1165511-A2 | METHOD OF PRODUCING HETEROCYCLIC CARBAMATES FROM AZA-HETEROCYCLIC COMPOUNDS AND CARBON DIOXIDE | GÖDECKE GMBH (DE) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000058286-A2 | METHOD OF PRODUCING HETEROCYCLIC CARBAMATES FROM AZA-HETEROCYCLIC COMPOUNDS AND CARBON DIOXIDE | Gödecke GmbH (DE) | 2000-10-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090036690-A1 | ORGANIC COMPOUNDS | TRPA1, IDO1, INMT | NOTUM 68/4885L3MBTL1 2651/4885TSHR 3438/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.