Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCPS | Q96C86 | 1/20 | 0.55 |
| ▸ | OGG1 | O15527 | 1/20 | 0.53 |
| ▸ | PDE5A | O76074 | 2/20 | 0.49 |
| ▸ | ACHE | P22303 | 2/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | GLA | P06280 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | NQO2 | P16083 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30918000 | 1.00 | DCPS (0.55) | DCPSOGG1PDE5AACHEBCHE | |
| SCHEMBL5314315 | 0.89 | DCPS (0.47) | DCPSOGG1PDE5AACHEBCHE | |
| SCHEMBL31579478 | 0.87 | HTR3A (0.56) | DCPSOGG1PDE5AHSD17B10ALDH1A1 | |
| SCHEMBL16822625 | 0.82 | ALDH1A1 (0.47) | DCPSOGG1PDE5AACHEBCHE | |
| SCHEMBL26318806 | 0.81 | OGG1 (0.55) | OGG1PDE5AACHEBCHEHSD17B10 | |
| SCHEMBL29937865 | 0.78 | GBA1 (0.42) | DCPSOGG1PDE5AHSD17B10ALDH1A1 | |
| SCHEMBL31391596 | 0.78 | OGG1 (0.53) | OGG1PDE5AACHEBCHEHSD17B10 | |
| SCHEMBL16404345 | 0.78 | OGG1 (0.53) | OGG1PDE5AACHEBCHEKDM4E | |
| SCHEMBL1369246 | 0.78 | OGG1 (0.53) | OGG1PDE5AACHEBCHEKDM4E | |
| SCHEMBL31052845 | 0.78 | OGG1 (0.53) | OGG1PDE5AACHEBCHEKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090069320-A1 | Substituted 4-Amino-Quinazoline Compounds with Metabotropic Glutamate Receptor Regulating Activity and Uses Thereof | GRUENENTHAL GMBH (DE) | 2009-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069320-A1 | Substituted 4-Amino-Quinazoline Compounds with Metabotropic Glutamate Receptor Regulating Activity and Uses Thereof | GRM1, GRIN1, GRM2 | DCPS 1621/4885OGG1 3665/4885PDE5A 1700/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.