Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | CCR2 | P41597 | 2/20 | 0.34 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.33 |
| ▸ | TERT | O14746 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL51501 | 0.67 | RPS6KA2 (0.37) | KMT2AHSD17B10 | |
| SCHEMBL31185878 | 0.66 | MAPT (0.42) | L3MBTL1ALDH1A1KMT2AMTNR1AMTNR1B | |
| SCHEMBL4554663 | 0.65 | RPS6KA3 (0.36) | L3MBTL1ALDH1A1KMT2ACCR2KDM4E | |
| SCHEMBL30954226 | 0.63 | ALDH1A1 (0.39) | ALDH1A1KMT2AKDM4EHPGDMEN1 | |
| SCHEMBL8326874 | 0.62 | HTR2A (0.42) | L3MBTL1ALDH1A1OXER1HPGDDAO | |
| SCHEMBL51354 | 0.62 | DAO (0.38) | L3MBTL1ALDH1A1KMT2ACCR2CA12 | |
| SCHEMBL2421457 | 0.60 | KDM4E (0.49) | ALDH1A1KMT2AKDM4EHPGDHSD17B10 | |
| SCHEMBL8324980 | 0.60 | HTR2A (0.42) | — | |
| SCHEMBL6689677 | 0.60 | L3MBTL1 (1.00) | L3MBTL1ALDH1A1KMT2ACCR2MTNR1A | |
| SCHEMBL31186094 | 0.59 | CYP2D6 (0.36) | ALDH1A1KMT2AKDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090130057-A1 | Compounds for the Treatment of Hepatitis C | BRISTOL-MYERS SQUIBB COMPANY | 2009-05-21 | — | — | US | claimed |
| EP-2518073-A1 | Compounds for the treatment of Hepatitis C | Bristol-Myers Squibb Company (US) | 2012-10-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090130057-A1 | Compounds for the Treatment of Hepatitis C | HAVCR2, HCCS, SLC10A1 | L3MBTL1 4160/4885ALDH1A1 163/4885KMT2A 4456/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.