Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 6/20 | 0.74 |
| ▸ | ALOX12 | P18054 | 6/20 | 0.74 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.60 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.60 |
| ▸ | KLK7 | P49862 | 1/20 | 0.58 |
| ▸ | XDH | P47989 | 1/20 | 0.57 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10562974 | 0.85 | ALOX15 (1.00) | ALOX15ALOX12PIK3CAKDM4EALDH1A1 | |
| SCHEMBL4194426 | 0.82 | ALOX15 (0.74) | ALOX15ALOX12PIK3CAKDM4EALDH1A1 | |
| SCHEMBL4300469 | 0.82 | ALOX15 (0.74) | ALOX15ALOX12PIK3CAKDM4EALDH1A1 | |
| SCHEMBL10486563 | 0.80 | ALOX15 (0.70) | ALOX15ALOX12PIK3CAKDM4EALDH1A1 | |
| SCHEMBL16227303 | 0.80 | ALOX15 (0.70) | ALOX15ALOX12PIK3CAKDM4EALDH1A1 | |
| SCHEMBL8983948 | 0.79 | ALDH1A1 (0.56) | ALOX15ALOX12PIK3CAKDM4EALDH1A1 | |
| SCHEMBL8983892 | 0.76 | ALDH1A1 (0.56) | ALOX15ALOX12PIK3CAKDM4EALDH1A1 | |
| SCHEMBL12325677 | 0.76 | ALOX15 (0.64) | ALOX15ALOX12KDM4EALDH1A1HPGD | |
| SCHEMBL10560725 | 0.75 | ALOX15 (1.00) | ALOX15ALOX12PIK3CAKDM4EALDH1A1 | |
| SCHEMBL14157759 | 0.75 | ALOX15 (0.58) | ALOX15ALOX12PIK3CAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090192152-A1 | Novel Antigiardial Agents and Methods of Use Thereof | UNIVERSITY OF MISSISSIPPI | 2009-07-30 | — | — | US | disclosed |
| US-7468445-B2 | Antigiardial agents and use thereof | UNIVERSITY OF MISSISSIPPI (US) | 2008-12-23 | — | — | US | disclosed |
| US-20060106091-A1 | Antigiardial agents and use thereof | THE UNIVERSITY OF MISSISSIPPI | 2006-05-18 | — | — | US | disclosed |
| WO-2004014886-A1 | ANTIGIARDIAL AGENTS AND USE THEREOF | UNIVERSITY OF MISSISSIPPI (US) | 2004-02-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060106091-A1 | Antigiardial agents and use thereof | GPER1, ENPP2, ALPI | ALOX15 336/4885ALOX12 385/4885PIK3CA 1459/4885 |
| US-20090192152-A1 | Novel Antigiardial Agents and Methods of Use Thereof | ENPP2, GPER1, ALPI | ALOX15 328/4885ALOX12 393/4885PIK3CA 1588/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.