SCHEMBL4300469

SCHEMBL4300469

Cc1c(O)ccc2c(=O)c(-c3ccccc3)coc12

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 6/20 0.74
ALOX12 P18054 6/20 0.74
PKM P14618 1/20 0.62
POLB P06746 2/20 0.61
CA12 O43570 1/20 0.58
TNF P01375 1/20 0.58
CA9 Q16790 1/20 0.58
NOD2 Q9HC29 1/20 0.58
NOD1 Q9Y239 1/20 0.58
ALDH1A1 P00352 4/20 0.57
KDM4E B2RXH2 3/20 0.57
HPGD P15428 2/20 0.57
HSD17B10 Q99714 2/20 0.57
XDH P47989 1/20 0.57
PFKFB3 Q16875 1/20 0.57
RCE1 Q9Y256 1/20 0.57
KLK7 P49862 1/20 0.55
PIK3CA P42336 3/20 0.55
NPC1 O15118 1/20 0.54
RAB9A P51151 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL330038 0.88 XDH (0.74) ALOX15ALOX12PKMPOLBCA12
SCHEMBL10562056 0.88 ALOX15 (0.79) ALOX15ALOX12PKMPOLBCA12
SCHEMBL232035 0.87 PKM (0.60) ALOX15ALOX12PKMPOLBCA12
SCHEMBL2072028 0.86 ALOX15 (0.65) ALOX15ALOX12PKMPOLBCA12
SCHEMBL5139795 0.86 ALOX15 (0.75) ALOX15ALOX12PKMPOLBCA12
SCHEMBL10562974 0.85 ALOX15 (1.00) ALOX15ALOX12PKMPOLBALDH1A1
SCHEMBL2070701 0.83 ALDH1A1 (0.69) ALOX15ALOX12PKMPOLBCA12
SCHEMBL4178094 0.82 ALOX15 (0.74) ALOX15ALOX12POLBALDH1A1KDM4E
SCHEMBL4194426 0.82 ALOX15 (0.74) ALOX15ALOX12POLBALDH1A1KDM4E
SCHEMBL18235039 0.82 ALOX15 (0.58) ALOX15ALOX12PKMPOLBCA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260128372-A1 NON-AQUEOUS ELECTROLYTE FOR LITHIUM SECONDARY BATTERY, AND LITHIUM SECONDARY BATTERY COMPRISING SAME LG CHEMICAL LTD (KR) 2026-05-07 US disclosed
EP-4576305-A1 NON-AQUEOUS ELECTROLYTE FOR LITHIUM SECONDARY BATTERY, AND LITHIUM SECONDARY BATTERY COMPRISING SAME LG CHEM, LTD. (KR) 2025-06-25 EP disclosed
CN-120153509-A Nonaqueous electrolyte for lithium secondary battery and lithium secondary battery comprising same 株式会社LG化学 2025-06-13 CN disclosed
CN-113185486-B Antitumor agent 3-aryl-4H-chromen-4-one for the treatment of cancer 肯塔基大学研究基金会 2024-05-10 CN disclosed
CN-113185486-A Antitumor 3-aryl-4H-chromen-4-ones for the treatment of cancer 肯塔基大学研究基金会 2021-07-30 CN disclosed
CN-107667100-B Antitumor 3-aryl-4H-chromen-4-ones for the treatment of cancer 肯塔基大学研究基金会 2021-06-08 CN disclosed
CN-107667100-A Antitumor 3-aryl-4H-chromen-4-ones for the treatment of cancer 肯塔基大学研究基金会 2018-02-06 CN disclosed
US-20090233999-A1 COMPOSITIONS AND THERAPEUTIC METHODS INVOLVING ISOFLAVONES AND ANALOGUES THEREOF NOVOGEN RESEARCH PTY LTD (AU) 2009-09-17 US disclosed
US-20080300298-A1 Honokiol Derivates For the Treatment of Proliferative Disorders NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2008-12-04 US disclosed
US-20080300298-A1 Honokiol Derivates For the Treatment of Proliferative Disorders NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2008-12-04 US disclosed
WO-2007115181-A9 COMPOUNDS EXHIBITING EFFLUX INHIBITOR ACTIVITY AND COMPOSITIONS AND USES THEREOF EASTMAN CHEM CO (US) 2008-04-03 WO disclosed
US-20070254859-A1 Compounds exhibiting efflux inhibitor activity and composition and uses thereof EASTMAN CHEMICAL COMPANY 2007-11-01 US disclosed
WO-2007115181-A2 COMPOUNDS EXHIBITING EFFLUX INHIBITOR ACTIVITY AND COMPOSITIONS AND USES THEREOF EASTMAN CHEMICAL COMPANY (US) 2007-10-11 WO disclosed
CN-1129445-A Isoflavone derivatives CHINOIN GYOGYSZER ES VEGYESZET (HU) 1996-08-21 CN disclosed
EP-0710234-A1 ISOFLAVONE DERIVATIVES CHINOIN LTD. (HU) 1996-05-08 EP disclosed
WO-1995003293-A1 ISOFLAVONE DERIVATIVES CHINOIN LTD. (HU) 1995-02-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070254859-A1 Compounds exhibiting efflux inhibitor activity and composition and uses thereof ABCC4, NCOA4, NR4A3 ALOX15 687/4885ALOX12 1247/4885PKM 3998/4885
US-20260128372-A1 NON-AQUEOUS ELECTROLYTE FOR LITHIUM SECONDARY BATTERY, AND LITHIUM SECONDARY BATTERY COMPRISING SAME CLCN2, CLIC1, RER1 ALOX15 2044/4885ALOX12 2193/4885PKM 4302/4885
US-20090233999-A1 COMPOSITIONS AND THERAPEUTIC METHODS INVOLVING ISOFLAVONES AND ANALOGUES THEREOF SHBG, OAT, APOB ALOX15 1586/4885ALOX12 1633/4885PKM 2178/4885
US-20080300298-A1 Honokiol Derivates For the Treatment of Proliferative Disorders CCNK, CDK3, CCNO ALOX15 526/4885ALOX12 508/4885PKM 728/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.