SCHEMBL4178440

SCHEMBL4178440

O=C(CCCCCCCCCCCCCCCCCO)O[C@@H]1[C@@H](O)[C@@H](O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)O[C@H](CO)[C@H]1O

nearest known ligand 0.56

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 1/20 0.56
▸ POLB P06746 1/20 0.56
▸ SMN1; SMN2 Q16637 1/20 0.56
▸ LGALS8 O00214 6/20 0.50
▸ LGALS3 P17931 1/20 0.43
▸ LGALS4 P56470 1/20 0.43
▸ IGF2R P11717 1/20 0.42
▸ MEN1 O00255 1/20 0.41
▸ KMT2A Q03164 1/20 0.41
▸ GJB2 P29033 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4199470 0.91 LGALS8 (0.50) LGALS8GJB2
SCHEMBL4185394 0.91 LGALS8 (0.50) LGALS8GJB2
SCHEMBL3393533 0.91 LGALS8 (0.50) LGALS8GJB2
SCHEMBL4181285 0.91 LGALS8 (0.50) LGALS8GJB2
SCHEMBL3388849 0.91 LGALS8 (0.50) LGALS8GJB2
SCHEMBL4185270 0.91 LGALS8 (0.50) LGALS8GJB2
SCHEMBL1723461 0.88 LGALS8 (0.47) KDM4EPOLBSMN1; SMN2LGALS8LGALS3
SCHEMBL2959758 0.85 TLR4 (0.54) GJB2
SCHEMBL15518255 0.85 LGALS8 (0.56) KDM4EPOLBSMN1; SMN2LGALS8LGALS3
SCHEMBL509203 0.84 TLR4 (0.50) LGALS8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090098172-A1 SURFACTANT, AND EMULSION COSMETIC AND LIPOSOME EACH CONTAINING THE SAME KAO CORPORATION (JP) 2009-04-16 — — US disclosed
US-20070292462-A1 Surfactant, and an emulsion-type cosmetic composition and a liposome containing said surfactant KAO CORPORATION (JP) 2007-12-20 — — US disclosed
US-20070160556-A1 Surfactant, and an emulsion-type cosmetic composition and a liposome containing said surfactant IKEMOTO TAKESHI 2007-07-12 — — US disclosed
US-20040022819-A1 Surfactant, and an emulsion-type cosmetic composition and a liposome containing said surfactant KAO CORPORATION (JP) 2004-02-05 — — US disclosed
US-6497898-B1 STABILITY, DRUG AND COSMETIC DELIVERY KANEBO LTD (JP) 2002-12-24 — — US disclosed
EP-0729781-B1 LIPOSOME COMPRISING A MEMBRANE WALL COMPOSED OF A TREHALOSE FATTY ACID ESTER KANEBO LTD (JP) 2002-08-07 — — EP disclosed
EP-0729781-A1 SURFACTANT, AND EMULSION COSMETIC AND LIPOSOME EACH CONTAINING THE SAME Ikemoto, Takeshi (JP) 1996-09-04 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070292462-A1 Surfactant, and an emulsion-type cosmetic composition and a liposome containing said surfactant TREH, LIPA, CUTA KDM4E 2706/4885POLB 2418/4885SMN1; SMN2 2531/4885
US-20040022819-A1 Surfactant, and an emulsion-type cosmetic composition and a liposome containing said surfactant TREH, LIPA, CUTA KDM4E 3003/4885POLB 2112/4885SMN1; SMN2 2165/4885
US-20070160556-A1 Surfactant, and an emulsion-type cosmetic composition and a liposome containing said surfactant TREH, LIPA, CUTA KDM4E 2706/4885POLB 2418/4885SMN1; SMN2 2531/4885
US-20090098172-A1 SURFACTANT, AND EMULSION COSMETIC AND LIPOSOME EACH CONTAINING THE SAME TREH, LIPA, SGMS1 KDM4E 2902/4885POLB 2132/4885SMN1; SMN2 1812/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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