SCHEMBL4181285

SCHEMBL4181285

CCCCCCCCCCCCCCCCCC(=O)O[C@@H]1[C@@H](O)[C@@H](O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)O[C@H](CO)[C@H]1O

nearest known ligand 0.53

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
LGALS8 O00214 2/20 0.50
GJB2 P29033 1/20 0.50
TLR4 O00206 4/20 0.49
TK2 O00142 2/20 0.49
LY96 Q9Y6Y9 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4185394 1.00 LGALS8 (0.50) LGALS8GJB2TLR4TK2LY96
SCHEMBL4199470 1.00 LGALS8 (0.50) LGALS8GJB2TLR4TK2LY96
SCHEMBL4185270 1.00 LGALS8 (0.50) LGALS8GJB2TLR4TK2LY96
SCHEMBL3393533 1.00 LGALS8 (0.50) LGALS8GJB2TLR4TK2LY96
SCHEMBL3388849 1.00 LGALS8 (0.50) LGALS8GJB2TLR4TK2LY96
SCHEMBL2959758 0.93 TLR4 (0.54) GJB2TLR4
SCHEMBL4181281 0.93 GJB2 (0.50) GJB2TLR4TK2LY96
SCHEMBL3393530 0.93 GJB2 (0.50) GJB2TLR4TK2LY96
SCHEMBL4199466 0.93 GJB2 (0.50) GJB2TLR4TK2LY96
SCHEMBL3388845 0.93 GJB2 (0.50) GJB2TLR4TK2LY96

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2314351-B1 Hair dye agent with improved skin tolerance HENKEL AG & CO KGAA (DE) 2014-12-17 EP claimed
US-20230265614-A1 WATER INSOLUBLE, HIGH MELTING POINT SACCHARIDE FATTY ACID ESTERS (SFAE) GREENTECH GLOBAL PTE. LTD. (SG) 2023-08-24 US disclosed
CN-116536379-A Preparation method and application of trehalose fatty acid monoester and diester 暨南大学 2023-08-04 CN disclosed
CN-115135307-A Carrier for cell delivery 株式会社ITO 2022-09-30 CN disclosed
US-11203005-B2 Method for producing water-absorbing polymer particles by suspension polymerization BASF SE (DE) 2021-12-21 US disclosed
CN-107406553-B Method for producing water-absorbing polymer particles by suspension polymerization 巴斯夫欧洲公司 2021-05-18 CN disclosed
CN-107438632-B Method for producing superabsorbent polymer particles 巴斯夫欧洲公司 2021-04-13 CN disclosed
CN-107257809-B Method for producing water-absorbing polymer particles by suspension polymerization 巴斯夫欧洲公司 2021-01-15 CN disclosed
US-10857256-B2 Method for producing super absorber particles BASF SE (DE) 2020-12-08 US disclosed
CN-107466302-B Method for agglomerating super-absorbent particles 巴斯夫欧洲公司 2020-12-04 CN disclosed
US-20070292462-A1 Surfactant, and an emulsion-type cosmetic composition and a liposome containing said surfactant KAO CORPORATION (JP) 2007-12-20 US disclosed
US-20070160556-A1 Surfactant, and an emulsion-type cosmetic composition and a liposome containing said surfactant IKEMOTO TAKESHI 2007-07-12 US disclosed
US-20050220726-A1 Use of sugar esters in cosmetic and/or pharmaceutical preparations COGNIS FRANCE S.A. (FR) 2005-10-06 US disclosed
US-20040022819-A1 Surfactant, and an emulsion-type cosmetic composition and a liposome containing said surfactant KAO CORPORATION (JP) 2004-02-05 US disclosed
US-6497898-B1 STABILITY, DRUG AND COSMETIC DELIVERY KANEBO LTD (JP) 2002-12-24 US disclosed
EP-0729781-B1 LIPOSOME COMPRISING A MEMBRANE WALL COMPOSED OF A TREHALOSE FATTY ACID ESTER KANEBO LTD (JP) 2002-08-07 EP disclosed
US-5721109-A DETECTION OF ANTIBODIES TO ACID-FREE BACTERIUM ANTIGEN SAWAI PHARMACEUTICAL CO., LTD. (JP) 1998-02-24 US disclosed
EP-0729781-A1 SURFACTANT, AND EMULSION COSMETIC AND LIPOSOME EACH CONTAINING THE SAME Ikemoto, Takeshi (JP) 1996-09-04 EP disclosed
EP-0407605-B1 USE OF A REAGENT FOR DETECTING ANTIBODY CORRESPONDING TO ACID-FAST BACTERIUM ANTIGEN SAWAI SEIYAKU KK (JP) 1995-09-13 EP disclosed
EP-0407605-A1 USE OF A REAGENT FOR DETECTING ANTIBODY CORRESPONDING TO ACID-FAST BACTERIUM ANTIGEN SAWAI PHARMACEUTICAL CO., LTD. (JP) 1991-01-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070292462-A1 Surfactant, and an emulsion-type cosmetic composition and a liposome containing said surfactant TREH, LIPA, CUTA LGALS8 806/4885GJB2 4097/4885TLR4 477/4885
US-20040022819-A1 Surfactant, and an emulsion-type cosmetic composition and a liposome containing said surfactant TREH, LIPA, CUTA LGALS8 828/4885GJB2 4049/4885TLR4 451/4885
US-20070160556-A1 Surfactant, and an emulsion-type cosmetic composition and a liposome containing said surfactant TREH, LIPA, CUTA LGALS8 806/4885GJB2 4097/4885TLR4 477/4885
US-20050220726-A1 Use of sugar esters in cosmetic and/or pharmaceutical preparations CUTA, SUCLG1, TREH LGALS8 175/4885GJB2 3366/4885TLR4 2866/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.