Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.63 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.63 |
| ▸ | AGXT | P21549 | 1/20 | 0.61 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.59 |
| ▸ | HTR6 | P50406 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 3/20 | 0.54 |
| ▸ | GRM5 | P41594 | 1/20 | 0.52 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.52 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.51 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8322225 | 0.86 | MAOB (0.58) | AGXTHRH3ALDH1A1TSHRMAOB | |
| SCHEMBL13202898 | 0.85 | RAB9A (0.67) | USP2MAPTMAPK1KMT2AESR2 | |
| SCHEMBL3103344 | 0.85 | MAOB (0.57) | AGXTHRH3ALDH1A1TSHRMAOB | |
| SCHEMBL4671546 | 0.82 | ADRB1 (0.59) | HTR6TP53MAOBGRM5ALOX5 | |
| SCHEMBL1263059 | 0.82 | AGXT (0.61) | MAPK1KMT2AAGXTALDH1A1TSHR | |
| SCHEMBL4671542 | 0.82 | ALOX5 (0.54) | USP2MAPTMAPK1KMT2AESR2 | |
| SCHEMBL6350404 | 0.82 | NPC1 (0.52) | USP2MAPTMAPK1KMT2AESR2 | |
| SCHEMBL22955186 | 0.82 | NPC1 (0.52) | USP2MAPTMAPK1KMT2AESR2 | |
| SCHEMBL12251546 | 0.81 | ADRA2C (0.57) | MAPTKMT2AAGXTALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL1532961 | 0.81 | ADRB1 (0.57) | HTR6MAOBGRM5ALOX5HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090069315-A1 | Use of Pyrazolo(1,5A)Pyrimidin-7-YL Amine Derivatives in the Treatment of Neurological Disorders | SIVASANKARAN RAJEEV | 2009-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069315-A1 | Use of Pyrazolo(1,5A)Pyrimidin-7-YL Amine Derivatives in the Treatment of Neurological Disorders | EPHA5, EPHA7, EPHA1 | USP2 4709/4885MAPT 582/4885MAPK1 1136/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.