SCHEMBL4179653

SCHEMBL4179653

Fc1ccc(B(Oc2cccc3cccnc23)c2ccc(F)cc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 7/20 0.57
NPC1 O15118 5/20 0.57
MEN1 O00255 3/20 0.57
KMT2A Q03164 3/20 0.57
KDM4E B2RXH2 6/20 0.46
GLRA3 O75311 1/20 0.46
METAP2 P50579 2/20 0.46
METAP1 P53582 2/20 0.46
MAPT P10636 6/20 0.44
LMNA P02545 7/20 0.43
SMN1; SMN2 Q16637 3/20 0.43
HTT P42858 2/20 0.43
ALDH1A1 P00352 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
GLO1 Q04760 1/20 0.43
HDAC6 Q9UBN7 1/20 0.42
GAA P10253 1/20 0.41
GMNN O75496 1/20 0.41
TP53 P04637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19849387 0.93 KMT2A (0.51) RAB9ANPC1MEN1KMT2AKDM4E
SCHEMBL4832908 0.93 RAB9A (0.51) RAB9ANPC1MEN1KMT2AKDM4E
SCHEMBL5165794 0.89 MEN1 (0.48) RAB9ANPC1MEN1KMT2AKDM4E
SCHEMBL5166506 0.88 RAB9A (0.47) RAB9ANPC1MEN1KMT2AKDM4E
SCHEMBL4169797 0.87 METAP2 (0.55) RAB9ANPC1MEN1KMT2AKDM4E
SCHEMBL4169850 0.86 LMNA (0.51) RAB9ANPC1MEN1KMT2AKDM4E
SCHEMBL5164459 0.86 RAB9A (0.44) RAB9ANPC1MEN1KMT2AKDM4E
SCHEMBL7062366 0.85 RAB9A (0.55) RAB9ANPC1MEN1KMT2AKDM4E
SCHEMBL1186836 0.85 RAB9A (0.43) RAB9ANPC1MEN1KMT2AKDM4E
SCHEMBL4169579 0.84 LMNA (0.48) RAB9ANPC1MEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090082561-A1 Methods For The Preparation Of Alkyl Diaryl Borinates And Complexed Diarylboronic Acids THE PENNSYLVANIA STATE RESEARCH FOUNDATION 2009-03-26 US claimed
US-20050080048-A1 Methods for the preparation of alkyl diaryl borinates and complexed diarylboronic acids PENN STATE RESEARCH FOUNDATION, THE 2005-04-14 US claimed
EP-1463739-A2 METHODS FOR THE PREPARATION OF ALKYL DIARYL BORINATES AND COMPLEXED DIARYLBORINIC ACIDS THE PENNSYLVANIA STATE RESEARCH FOUNDATION (US) 2004-10-06 EP claimed
EP-1420021-A1 DNA Methyltransferase inhibitors The Penn State Research Foundation (US) 2004-05-19 EP claimed
EP-1339725-A2 DNA METHYL TRANSFERASE INHIBITORS THE PENN STATE RESEARCH FOUNDATION (US) 2003-09-03 EP claimed
WO-2003059916-A2 METHODS FOR THE PREPARATION OF ALKYL DIARYL BORINATES AND COMPLEXED DIARYLBORINIC ACIDS THE PENNSYLVANIA STATE RESEARCH FOUNDATION (US) 2003-07-24 WO claimed
WO-2002044184-A2 DNA METHYL TRANSFERASE INHIBITORS THE PENN STATE RESEARCH FOUNDATION (US) 2002-06-06 WO claimed
WO-2018133921-A1 ORGAN PRESERVATION AND/OR PERFUSION SOLUTIONS XVIVO PERFUSION AB (SE) 2018-07-26 WO disclosed
US-7405304-B2 Methods for the preparation of alkyl diaryl borinates and complexed diarylboronic acids THE PENN STATE RESEARCH FOUNDATION (US) 2008-07-29 US disclosed
JP-2008069162-A DNA METHYL TRANSFERASE INHIBITOR PENN STATE RESEARCH FOUNDATION 2008-03-27 JP disclosed
EP-1179435-B1 Reversible thermochromic composition having improved light-fastness and product comprising same PILOT INK CO LTD (JP) 2006-11-29 EP disclosed
EP-1339725-B1 DNA METHYL TRANSFERASE INHIBITORS PENN STATE RES FOUND (US) 2006-11-22 EP disclosed
EP-1038939-B1 CHEMILUMINESCENT REAGENTS AND CHEMILUMINESCENCE ANALYSIS METHODS WITH THE USE OF THE SAME DAINICHISEIKA COLOR CHEM (JP) 2006-11-02 EP disclosed
WO-2003059916-A2 METHODS FOR THE PREPARATION OF ALKYL DIARYL BORINATES AND COMPLEXED DIARYLBORINIC ACIDS THE PENNSYLVANIA STATE RESEARCH FOUNDATION (US) 2003-07-24 WO disclosed
WO-2002044184-A2 DNA METHYL TRANSFERASE INHIBITORS THE PENN STATE RESEARCH FOUNDATION (US) 2002-06-06 WO disclosed
US-6395503-B1 LUMINESCENT REAGENT FOR USE IN DETECTION OF AND QUANTITATIVE ANALYSIS OF VARIOUS TYPES OF PARTICLES IN SAMPLE DAINICHISEIKA COLOR & CHEMICALS MFG. CO., LTD. (JP) 2002-05-28 US disclosed
EP-1179435-A1 Reversible thermochromic composition having improved light-fastness and product comprising same The Pilot Ink Co., Ltd. (JP) 2002-02-13 EP disclosed
EP-1038939-A1 CHEMILUMINESCENT REAGENTS AND CHEMILUMINESCENCE ANALYSIS METHODS WITH THE USE OF THE SAME DAINICHISEIKA COLOR & CHEMICALS MFG. CO. LTD. (JP) 2000-09-27 EP disclosed
EP-0914153-A1 MULTIVALENT DTP-POLIO VACCINES CONNAUGHT LABORATORIES LIMITED (CA) 1999-05-12 EP disclosed
WO-1998000167-A1 MULTIVALENT DTP-POLIO VACCINES CONNAUGHT LABORATORIES LIMITED (CA) 1998-01-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090082561-A1 Methods For The Preparation Of Alkyl Diaryl Borinates And Complexed Diarylboronic Acids BCL6B, BLVRB, SSB RAB9A 1122/4885NPC1 782/4885MEN1 227/4885
US-20050080048-A1 Methods for the preparation of alkyl diaryl borinates and complexed diarylboronic acids BCL6B, BLVRB, SSB RAB9A 1122/4885NPC1 782/4885MEN1 227/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.