Glycerin

Glycerin

SCHEMBL4180811

CC(=O)CO.NO.OCC(O)CO

nearest known ligand 0.50

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Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.50
LMNA P02545 4/20 0.50
TDP1 Q9NUW8 3/20 0.40
THRB P10828 1/20 0.35
OR51E2 Q9H255 1/20 0.33
TRPA1 O75762 1/20 0.32
KDM4E B2RXH2 1/20 0.31
DUSP3 P51452 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
SLC22A16 Q86VW1 1/20 0.31
USP2 O75604 1/20 0.30
SLCO1B1 Q9Y6L6 1/20 0.30
ALOX15 P16050 1/20 0.30
BLM P54132 1/20 0.30
PMP22 Q01453 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glycerin SCHEMBL1936682 0.94 ALDH1A1 (0.56) ALDH1A1LMNATDP1THRBOR51E2
E968 SCHEMBL21271384 0.86 LMNA (0.47) ALDH1A1LMNATDP1THRBOR51E2
Glycerin SCHEMBL19182834 0.82 LMNA (0.56) ALDH1A1LMNATDP1THRBOR51E2
Propylene Glycol SCHEMBL1079956 0.82 TDP1 (0.62) ALDH1A1LMNATDP1OR51E2TRPA1
Glycerin SCHEMBL1831824 0.82 LMNA (0.64) ALDH1A1LMNATDP1THRBOR51E2
Glycerin SCHEMBL93722 0.82 LMNA (0.64) ALDH1A1LMNATDP1THRBOR51E2
Glycerin SCHEMBL4554867 0.82 LMNA (0.64) ALDH1A1LMNATDP1THRBOR51E2
Glycerin SCHEMBL1513106 0.80 ALDH1A1 (0.59) ALDH1A1LMNATDP1THRBOR51E2
Glycerin SCHEMBL28686701 0.80 ALDH1A1 (0.53) ALDH1A1LMNATDP1THRBOR51E2
Glycerin SCHEMBL8025707 0.80 ALDH1A1 (0.59) ALDH1A1LMNATDP1THRBOR51E2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2024321-A2 PROCESSES FOR CONVERTING GLYCEROL TO AMINO ALCOHOLS The Procter and Gamble Company (US) 2009-02-18 EP disclosed
WO-2007146143-A2 PROCESSES FOR CONVERTING GLYCEROL TO AMINO ALCOHOLS THE PROCTER & GAMBLE COMPANY (US) 2007-12-21 WO disclosed