Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.44 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.41 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28172418 | 0.86 | CTSD (0.47) | CTSDCA2CA1CA9ALDH1A1 | |
| SCHEMBL24141996 | 0.84 | TSHR (0.42) | CA2CA1CA9ALDH1A1GAA | |
| SCHEMBL8104116 | 0.82 | GAA (0.55) | CA2ALDH1A1GAALMNATDP1 | |
| SCHEMBL24925442 | 0.82 | GAA (0.67) | CA1CA9ALDH1A1GAALMNA | |
| SCHEMBL28172417 | 0.82 | MAPT (0.46) | CTSDCA2CA1CA9ALDH1A1 | |
| SCHEMBL10946343 | 0.81 | LMNA (0.43) | ALDH1A1GAALMNATDP1TSHR | |
| SCHEMBL7223846 | 0.81 | L3MBTL1 (0.49) | CA1CA9ALDH1A1GAALMNA | |
| SCHEMBL1128084 | 0.81 | LMNA (0.70) | CTSDCA2CA1CA9ALDH1A1 | |
| SCHEMBL14726030 | 0.80 | GAA (0.46) | ALDH1A1GAALMNATDP1TSHR | |
| SCHEMBL16473851 | 0.80 | TSHR (0.45) | ALDH1A1GAALMNATSHRITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018149419-A1 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | RQX PHARMACEUTICALS, INC. (US) | 2018-08-23 | — | — | WO | disclosed |
| US-20120022083-A1 | SMALL MOLECULE MODULATORS OF CELL ADHESION | ADHEREX TECHNOLOGIES, INC. (CA) | 2012-01-26 | — | — | US | disclosed |
| US-20110046101-A1 | BATE-LACTAMASE INHIBITORS | DMITRIENKO GARY I | 2011-02-24 | — | — | US | disclosed |
| US-20090291967-A1 | SMALL MOLECULE MODULATORS OF CELL ADHESION | ADHEREX TECHNOLOGIES, INC. (CA) | 2009-11-26 | — | — | US | disclosed |
| US-7141106-B2 | Ink jet printing composition comprising a dye containing hydrazine or hydrazide | FUJIFILM IMAGING COLORANTS LIMITED (GB) | 2006-11-28 | — | — | US | disclosed |
| US-20040134382-A1 | Ink jet printing composition comprising a dye containing hydrazine or hydrazide | FUJIFILM IMAGING COLORANTS LIMITED (GB) | 2004-07-15 | — | — | US | disclosed |
| WO-2002070609-A1 | INK JET PRINTING COMPOSITION COMPRISING A DYE CONTAINING HYDRAZINE OR HYDRAZIDE | AVECIA LIMITED (GB) | 2002-09-12 | — | — | WO | disclosed |
| EP-0361645-B1 | ORGANIC HYDRAZINE DERIVATIVES FOR PHARMACEUTICAL USE | ROHM AND HAAS COMPANY (US) | 1993-09-29 | — | — | EP | disclosed |
| EP-0236618-B1 | INSECTICIDAL N'-SUBSTITUTED-N,N'-DIACYLHYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-02-27 | — | — | EP | disclosed |
| EP-0361645-A2 | Organic hydrazine derivatives for pharmaceutical use | ROHM AND HAAS COMPANY (US) | 1990-04-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090291967-A1 | SMALL MOLECULE MODULATORS OF CELL ADHESION | CDH1, EPCAM, ICAM1 | CTSD 2003/4885CA2 1079/4885CA1 759/4885 |
| US-20110046101-A1 | BATE-LACTAMASE INHIBITORS | OXA1L, MGAM, PREP | CTSD 349/4885CA2 2165/4885CA1 2889/4885 |
| US-20120022083-A1 | SMALL MOLECULE MODULATORS OF CELL ADHESION | CDH1, EPCAM, ICAM1 | CTSD 2003/4885CA2 1079/4885CA1 759/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.