Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | HTR7 | P34969 | 1/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.47 |
| ▸ | DRD2 | P14416 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4177226 | 0.97 | LTA4H (0.58) | LTA4HLMNAHTTKDM4EALDH1A1 | |
| SCHEMBL4184816 | 0.91 | KDM4E (0.59) | LTA4HLMNAHTTKDM4EALDH1A1 | |
| SCHEMBL4185349 | 0.88 | LTA4H (0.55) | LTA4HLMNAHTTALDH1A1KMT2A | |
| SCHEMBL4182932 | 0.88 | KDM4E (0.62) | LTA4HLMNAHTTKDM4EALDH1A1 | |
| SCHEMBL4177277 | 0.88 | LTA4H (0.67) | LTA4HLMNAHTTKDM4EALDH1A1 | |
| SCHEMBL4173098 | 0.84 | LTA4H (0.59) | LTA4HKDM4EALDH1A1HRH3L3MBTL1 | |
| SCHEMBL4181640 | 0.84 | LTA4H (0.71) | LTA4HLMNAHTTKDM4EALDH1A1 | |
| SCHEMBL1728667 | 0.83 | HTR1A (0.45) | EPHX2L3MBTL1HTR1AHTR7DRD2 | |
| SCHEMBL4178466 | 0.82 | HRH1 (0.50) | LMNAHTTKDM4EKMT2AHRH3 | |
| SCHEMBL1730296 | 0.80 | HTR1A (0.46) | LMNAHTTKDM4EEPHX2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090221607-A1 | Piperazine Derivatives | M'S SCIENCE CORPORATION (JP) | 2009-09-03 | — | — | US | claimed |
| US-20090221607-A1 | Piperazine Derivatives | M'S SCIENCE CORPORATION (JP) | 2009-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090221607-A1 | Piperazine Derivatives | SIGMAR1, OPRL1, OPRK1 | LTA4H 2891/4885LMNA 3325/4885HTT 3102/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.