SCHEMBL418238

SCHEMBL418238

C(=C/CSc1ccccc1)\CSc1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.57
MAPK1 P28482 1/20 0.57
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
FFAR1 O14842 1/20 0.46
SMN1; SMN2 Q16637 4/20 0.43
HPGD P15428 2/20 0.43
MAOB P27338 2/20 0.43
MAPT P10636 1/20 0.43
MGLL Q99685 1/20 0.43
HSD17B10 Q99714 1/20 0.43
MAOA P21397 1/20 0.43
LMNA P02545 1/20 0.41
TSHR P16473 1/20 0.41
RAB9A P51151 5/20 0.39
NPC1 O15118 4/20 0.39
TDP1 Q9NUW8 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
CYP1A2 P05177 2/20 0.39
CYP3A4 P08684 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL418239 1.00 ALDH1A1 (0.57) ALDH1A1MAPK1MEN1KMT2AFFAR1
SCHEMBL13138452 0.89 ALDH1A1 (0.46) ALDH1A1MAPK1MEN1KMT2AFFAR1
SCHEMBL14072417 0.89 ALDH1A1 (0.46) ALDH1A1MAPK1MEN1KMT2AFFAR1
SCHEMBL15068449 0.85 ALDH1A1 (0.48) ALDH1A1MAPK1MEN1KMT2AFFAR1
SCHEMBL10858079 0.85 ALDH1A1 (0.48) ALDH1A1MAPK1MEN1KMT2AFFAR1
SCHEMBL10398046 0.85 ALDH1A1 (0.48) ALDH1A1MAPK1MEN1KMT2AFFAR1
SCHEMBL8649390 0.85 ALDH1A1 (0.48) ALDH1A1MAPK1MEN1KMT2AFFAR1
SCHEMBL8649391 0.85 ALDH1A1 (0.48) ALDH1A1MAPK1MEN1KMT2AFFAR1
SCHEMBL6916286 0.84 RAB9A (0.59) ALDH1A1MAPK1KMT2ASMN1; SMN2HPGD
SCHEMBL6916282 0.84 RAB9A (0.59) ALDH1A1MAPK1KMT2ASMN1; SMN2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 264 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12623478-B2 Thermosensitive recording layer forming liquid, thermosensitive recording medium and production method thereof, and image recording method RICOH COMPANY, LTD. (JP) 2026-05-12 US disclosed
WO-2026087975-A1 THERMOSENSITIVE RECORDING MEDIUM AND IMAGE RECORDING METHOD RICOH COMPANY, LTD. (JP) 2026-04-30 WO disclosed
EP-4022391-B1 HEAT SENSITIVE RECORDING MATERIAL WITH NON-PHENOLIC COLOR DEVELOPERS SOLENIS TECHNOLOGIES CAYMAN LP (KY) 2026-03-04 EP disclosed
EP-4676749-A1 THERMOSENSITIVE RECORDING MEDIUM, METHOD FOR PRODUCING THERMOSENSITIVE RECORDING MEDIUM, AND ARTICLE COMPRISING THE THERMOSENSITIVE RECORDING MEDIUM Ricoh Company, Ltd. (JP) 2026-01-14 EP disclosed
EP-4420887-B1 THERMOSENSITIVE RECORDING MEDIUM RICOH CO LTD (JP) 2025-10-15 EP disclosed
US-20250289259-A1 THERMOSENSITIVE RECORDING MEDIUM FOR LINERLESS LABEL RICOH COMPANY, LTD. (JP) 2025-09-18 US disclosed
US-20250162340-A1 THERMOSENSITIVE RECORDING MEDIUM RICOH COMPANY, LTD. (JP) 2025-05-22 US disclosed
EP-3636446-B1 RECORDING MATERIAL, RECORDING SHEET AND USE OF A COMPOUND AS COLOUR-DEVELOPING AGENT NIPPON SODA CO (JP) 2025-04-16 EP disclosed
US-12275263-B2 Thermosensitive recording medium and method for producing thermosensitive recording medium RICOH COMPANY, LTD. (JP) 2025-04-15 US disclosed
US-20250050671-A1 THERMOSENSITIVE RECORDING LAYER FORMING LIQUID, THERMOSENSITIVE RECORDING MEDIUM AND PRODUCTION METHOD THEREOF, AND IMAGE RECORDING METHOD RICOH COMPANY, LTD. (JP) 2025-02-13 US disclosed
US-5200385-A Comprising leuco dye, color developer and water soluble alkylphosphate lubricants; antifogging, smoothness RICOH COMPANY, LTD. (JP) 1993-04-06 US disclosed
US-5194418-A A support with a colored layer containing a leuco dye and a dye developer and an overcoating of a crosslinkable resin RICOH COMPANY, LTD. (JP) 1993-03-16 US disclosed
US-5151404-A Heat sensitive coloring layers on supports RICOH COMPANY, LTD. (JP) 1992-09-29 US disclosed
US-5126486-A Color developers for leuco dyes in thermal printing RICOH COMPANY, LTD. (JP) 1992-06-30 US disclosed
US-5084593-A Cyanine, aniline dyes for heat sensitive recording elements RICOH COMPANY, LTD. (JP) 1992-01-28 US disclosed
US-5043313-A Mixture of leuco dye and diphenyl polyhydroxy sulfone compound RICOH COMPANY, LTD. (JP) 1991-08-27 US disclosed
US-5008238-A Thermosensitive material with phenolic developer RICOH COMPANY, LTD. (JP) 1991-04-16 US disclosed
US-4985345-A LEUCO DYES, BAR CODE READER RICOH COMPANY, LTD. (JP) 1991-01-15 US disclosed
US-4985394-A LEUCO DYE, PROTECTIVE LAYER OF SILICA AND CALCIUM CARBONATE AND WATER SOLUBLE BINDER, GLOSS RICOH COMPANY, LTD. (JP) 1991-01-15 US disclosed
US-4978651-A With a colorless or light colored leuco dye for inducing color formation RICOH COMPANY, LTD. (JP) 1990-12-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12623478-B2 Thermosensitive recording layer forming liquid, thermosensitive recording medium and production method thereof, and image recording method TRPA1, ASIC1, LRBA ALDH1A1 431/4885MAPK1 308/4885MEN1 2981/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.