Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.60 |
| ▸ | FAAH | O00519 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4070011 | 1.00 | ALDH1A1 (0.64) | ALDH1A1RAB9AEPHX1FAAHMEN1 | |
| SCHEMBL4175464 | 1.00 | ALDH1A1 (0.64) | ALDH1A1RAB9AEPHX1FAAHMEN1 | |
| SCHEMBL2383573 | 0.99 | ALDH1A1 (0.61) | ALDH1A1RAB9AEPHX1FAAHMEN1 | |
| SCHEMBL2382987 | 0.93 | EPHX2 (0.53) | ALDH1A1RAB9AEPHX1 | |
| SCHEMBL31417142 | 0.87 | MAPT (0.53) | ALDH1A1RAB9AEPHX1KMT2A | |
| SCHEMBL25994 | 0.86 | MGLL (0.47) | ALDH1A1RAB9AEPHX1 | |
| SCHEMBL27755801 | 0.84 | FAAH (0.63) | ALDH1A1RAB9AEPHX1FAAH | |
| SCHEMBL3064575 | 0.84 | EPHX2 (0.47) | ALDH1A1RAB9AEPHX1 | |
| SCHEMBL12436790 | 0.84 | MGLL (0.48) | ALDH1A1RAB9AEPHX1 | |
| SCHEMBL29157993 | 0.83 | DRD2 (0.52) | ALDH1A1RAB9AEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009086835-A1 | NOVEL CYANOGUANIDINES | TOPOTARGET A/S (DK) | 2009-07-16 | — | — | WO | disclosed |
| WO-2009086835-A1 | NOVEL CYANOGUANIDINES | TOPOTARGET A/S (DK) | 2009-07-16 | — | — | WO | disclosed |