Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.52 |
| ▸ | CES1 | P23141 | 3/20 | 0.52 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.50 |
| ▸ | PPARG | P37231 | 7/20 | 0.50 |
| ▸ | PPARD | Q03181 | 7/20 | 0.50 |
| ▸ | PPARA | Q07869 | 7/20 | 0.50 |
| ▸ | TSHR | P16473 | 5/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TLR2 | O60603 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | FABP4 | P15090 | 2/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.50 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | PDE4A | P27815 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL115903 | 1.00 | CES2 (0.52) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL2784780 | 1.00 | CES2 (0.52) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL9787371 | 1.00 | CES2 (0.52) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL906530 | 1.00 | CES2 (0.52) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL11596235 | 1.00 | CES2 (0.52) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL9786182 | 1.00 | CES2 (0.52) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL10693208 | 1.00 | CES2 (0.52) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL2281929 | 1.00 | CES2 (0.52) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL3335968 | 0.97 | CES2 (0.50) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL11414513 | 0.97 | CES2 (0.50) | CES2CES1GPR84PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150118272-A1 | METHODS FOR ENHANCING COSMETIC OR DERMATOLOGICAL NOVEL COSMETIC OR DERMATOLOGICAL COMPOSITIONS CONTAINING A DIBENZOYL METHANE DERIVATIVE BY THE ADDITION OF MODIFIED TITANIUM DIOXIDE PARTICLES | DSM IP ASSETS B.V. (NL) | 2015-04-30 | — | — | US | disclosed |
| EP-2121611-B1 | UV-filter compounds based on alpha,beta-dihydroxyketones | DSM IP ASSETS BV (NL) | 2015-04-15 | — | — | EP | disclosed |
| US-8765967-B2 | Microcapsules with UV filter activity and process for producing them | DSM IP ASSETS B.V. (NE) | 2014-07-01 | — | — | US | disclosed |
| EP-1959914-B1 | COSMETIC OR DERMATOLOGICAL COMPOSITIONS COMPRISING MODIFIED TITANIUM DIOXIDE PARTICLES | DSM IP ASSETS BV (NL) | 2014-05-21 | — | — | EP | disclosed |
| US-8680147-B2 | Compositions | DSM IP ASSETS B.V. (NL) | 2014-03-25 | — | — | US | disclosed |
| EP-1885769-B1 | NOVEL POLYSILOXANE SUNSCREENS | DSM IP ASSETS BV (NL) | 2013-08-28 | — | — | EP | disclosed |
| US-20120294916-A1 | NOVEL COSMETIC OR DERMATOLOGICAL COMBINATIONS COMPRISING MODIFIED TITANIUM DIOXIDE PARTICLES | DSM IP ASSETS B.V. (NL) | 2012-11-22 | — | — | US | disclosed |
| US-8278459-B2 | UV-filter compounds | DSM IP ASSETS B.V. (NL) | 2012-10-02 | — | — | US | disclosed |
| EP-1899015-B1 | COMPOSITION WITH TIGHT CAPSULES CONTAINING A SUNSCREEN AGENT | DSM IP ASSETS BV (NL) | 2012-03-21 | — | — | EP | disclosed |
| EP-1722863-B1 | MICROCAPSULES WITH UV FILTER ACTIVITY AND PROCESS FOR PRODUCING THEM | DSM IP ASSETS BV (NL) | 2012-02-08 | — | — | EP | disclosed |
| WO-2006128614-A1 | NOVEL POLYSILOXANE SUNSCREENS | DSM IP ASSETS B.V. (NL) | 2006-12-07 | — | — | WO | disclosed |
| EP-1722863-A1 | MICROCAPSULES WITH UV FILTER ACTIVITY AND PROCESS FOR PRODUCING THEM | DSM IP Assets B.V. (NL) | 2006-11-22 | — | — | EP | disclosed |
| WO-2006100018-A1 | POLYSILOXANE COATED METAL OXIDE PARTICLES | DSM IP ASSETS B.V. (NL) | 2006-09-28 | — | — | WO | disclosed |
| WO-2006099952-A2 | CHROMOPHORE COATED METAL OXIDE PARTICLES | DSM IP ASSETS B.V. (NL) | 2006-09-28 | — | — | WO | disclosed |
| EP-1474098-B1 | SUNSCREEN COMPOSITIONS AS WELL AS DIHYDROPYRIDINES AND DIHYDROPYRANES | DSM IP ASSETS BV (NL) | 2006-08-02 | — | — | EP | disclosed |
| US-20060073106-A1 | Novel stabilized cinnamic ester sunscreen compositions | DSM IP ASSETS B.V. (NL) | 2006-04-06 | — | — | US | disclosed |
| EP-1589940-A1 | NOVEL STABILIZED CINNAMIC ESTER SUNSCREEN COMPOSITIONS | DSM IP Assets B.V. (NL) | 2005-11-02 | — | — | EP | disclosed |
| WO-2005053631-A1 | MICROCAPSULES WITH UV FILTER ACTIVITY AND PROCESS FOR PRODUCING THEM | DSM IP ASSETS B.V. (NL) | 2005-06-16 | — | — | WO | disclosed |
| US-20050019278-A1 | Sunscreen compositions as well as dihydropyridines and dihydropyranes | ROCHE VITAMINS AG (CH) | 2005-01-27 | — | — | US | disclosed |
| WO-2004069216-A1 | NOVEL STABILIZED CINNAMIC ESTER SUNSCREEN COMPOSITIONS | DSM IP ASSETS B.V. (CH) | 2004-08-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060073106-A1 | Novel stabilized cinnamic ester sunscreen compositions | SUN2, NISCH, BCAS2 | CES2 164/4885CES1 174/4885GPR84 4553/4885 |
| US-20050019278-A1 | Sunscreen compositions as well as dihydropyridines and dihydropyranes | DHPS, DSG1, DHODH | CES2 3524/4885CES1 1980/4885GPR84 3748/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.