Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | LDHA | P00338 | 1/20 | 0.38 |
| ▸ | TPMT | P51580 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4170593 | 0.83 | KMT2A (0.45) | LTA4HKMT2AFFAR1 | |
| SCHEMBL4187784 | 0.82 | L3MBTL1 (0.47) | POLBL3MBTL1KMT2AFFAR1 | |
| SCHEMBL4173523 | 0.82 | PPARG (0.50) | LTA4HKMT2A | |
| SCHEMBL4180718 | 0.82 | PPARG (0.47) | LTA4HFFAR1 | |
| SCHEMBL4187187 | 0.82 | LDHA (0.55) | RXRARXRBLDHACA1CA2 | |
| Hydrochloric Acid SCHEMBL7379173 | 0.72 | SLC6A4 (0.41) | CA1CA2CA9SLC6A4 | |
| SCHEMBL5720978 | 0.72 | ANPEP (0.43) | TPMTPOLBTDP1KIF11KMT2A | |
| SCHEMBL5720976 | 0.72 | ANPEP (0.43) | TPMTPOLBTDP1KIF11KMT2A | |
| SCHEMBL4183099 | 0.71 | PPARG (0.46) | LDHA | |
| SCHEMBL11884497 | 0.69 | PARP10 (0.41) | RXRARXRBLDHATPMTCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090227680-A1 | Amino Acid Derivatives | PFIZER, INC. (US) | 2009-09-10 | — | — | US | claimed |
| EP-1951655-A2 | AMINO ACID DERIVATIVES | Pfizer Limited (GB) | 2008-08-06 | — | — | EP | claimed |
| WO-2007057767-A2 | AMINO ACID DERIVATIVES | PFIZER LIMITED (GB) | 2007-05-24 | — | — | WO | claimed |
| US-20090227680-A1 | Amino Acid Derivatives | PFIZER, INC. (US) | 2009-09-10 | — | — | US | disclosed |
| EP-1951655-A2 | AMINO ACID DERIVATIVES | Pfizer Limited (GB) | 2008-08-06 | — | — | EP | disclosed |
| WO-2007057767-A2 | AMINO ACID DERIVATIVES | PFIZER LIMITED (GB) | 2007-05-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090227680-A1 | Amino Acid Derivatives | OPRL1, OPRK1, AVPR1A | RXRA 1339/4885RXRB 2420/4885LDHA 784/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.