SCHEMBL4183281

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4189350	0.85	ALOX5 (0.47)	GAAALDH1A1GFEREPHX2
	SCHEMBL21807162	0.81	ALDH1A1 (0.47)	GAAALDH1A1GFERCYP4F2CYP4A11
	SCHEMBL3668882	0.79	GAA (0.72)	GAAALDH1A1GFERHSP90AB1CYP4F2
	SCHEMBL29446278	0.79	GAA (0.72)	GAAALDH1A1GFERHSP90AB1CYP4F2
	SCHEMBL31284885	0.78	GAA (0.44)	GAAALDH1A1GFERHSP90AB1CYP4F2
	SCHEMBL11567034	0.77	PTGDR (0.52)	GAAALDH1A1GFERHSP90AB1CYP4F2
	Methyl Alcohol SCHEMBL27946196	0.77	GAA (0.70)	GAAALDH1A1GFERHSP90AB1CYP4F2
	SCHEMBL17080063	0.77	SLC7A5 (0.50)	GAAALDH1A1GFERHSP90AB1CYP4F2
	SCHEMBL4183160	0.76	DRD2 (0.47)	GAAALDH1A1GFERHSP90AB1CYP4F2
	SCHEMBL27721931	0.76	CYP3A4 (0.50)	ALDH1A1TYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.