Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | CHUK | O15111 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | PNP | P00491 | 1/20 | 0.33 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.33 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.33 |
| ▸ | CCR7 | P32248 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27244201 | 0.79 | PGK1 (0.33) | CYP3A4PKMALDH1A1MEN1KMT2A | |
| SCHEMBL27243746 | 0.76 | MAT2A (0.33) | — | |
| SCHEMBL5803392 | 0.75 | HPRT1 (0.33) | — | |
| SCHEMBL12894751 | 0.73 | ALDH1A1 (0.32) | ALDH1A1MEN1KMT2A | |
| SCHEMBL18325718 | 0.72 | MAT2A (0.37) | CHUKALDH1A1 | |
| SCHEMBL22500804 | 0.72 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL1225985 | 0.71 | GDA (0.36) | ALDH1A1TDO2 | |
| SCHEMBL2852189 | 0.69 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL3812513 | 0.69 | BTK (0.37) | — | |
| SCHEMBL4183696 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090082561-A1 | Methods For The Preparation Of Alkyl Diaryl Borinates And Complexed Diarylboronic Acids | THE PENNSYLVANIA STATE RESEARCH FOUNDATION | 2009-03-26 | — | — | US | disclosed |
| US-20090082561-A1 | Methods For The Preparation Of Alkyl Diaryl Borinates And Complexed Diarylboronic Acids | THE PENNSYLVANIA STATE RESEARCH FOUNDATION | 2009-03-26 | — | — | US | disclosed |
| US-20090082561-A1 | Methods For The Preparation Of Alkyl Diaryl Borinates And Complexed Diarylboronic Acids | THE PENNSYLVANIA STATE RESEARCH FOUNDATION | 2009-03-26 | — | — | US | disclosed |
| US-7405304-B2 | Methods for the preparation of alkyl diaryl borinates and complexed diarylboronic acids | THE PENN STATE RESEARCH FOUNDATION (US) | 2008-07-29 | — | — | US | disclosed |
| US-7405304-B2 | Methods for the preparation of alkyl diaryl borinates and complexed diarylboronic acids | THE PENN STATE RESEARCH FOUNDATION (US) | 2008-07-29 | — | — | US | disclosed |
| US-7405304-B2 | Methods for the preparation of alkyl diaryl borinates and complexed diarylboronic acids | THE PENN STATE RESEARCH FOUNDATION (US) | 2008-07-29 | — | — | US | disclosed |
| CN-1325504-C | Methods for the preparation of alkyl diaryl borinates and complexed diarylboronic acids | PENNSYLVANIA STATE RES FOUNDAT (US) | 2007-07-11 | — | — | CN | disclosed |
| CN-1639170-A | Process for preparing alkyl diarylborates and complexed diarylboronic acids | PENNSYLVANIA STATE RES FOUNDAT (US) | 2005-07-13 | — | — | CN | disclosed |
| US-20050080048-A1 | Methods for the preparation of alkyl diaryl borinates and complexed diarylboronic acids | PENN STATE RESEARCH FOUNDATION, THE | 2005-04-14 | — | — | US | disclosed |
| EP-1463739-A2 | METHODS FOR THE PREPARATION OF ALKYL DIARYL BORINATES AND COMPLEXED DIARYLBORINIC ACIDS | THE PENNSYLVANIA STATE RESEARCH FOUNDATION (US) | 2004-10-06 | — | — | EP | disclosed |
| WO-2003059916-A2 | METHODS FOR THE PREPARATION OF ALKYL DIARYL BORINATES AND COMPLEXED DIARYLBORINIC ACIDS | THE PENNSYLVANIA STATE RESEARCH FOUNDATION (US) | 2003-07-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090082561-A1 | Methods For The Preparation Of Alkyl Diaryl Borinates And Complexed Diarylboronic Acids | BCL6B, BLVRB, SSB | KDM4E 2810/4885MAPK1 3171/4885CHUK 3243/4885 |
| US-20050080048-A1 | Methods for the preparation of alkyl diaryl borinates and complexed diarylboronic acids | BCL6B, BLVRB, SSB | KDM4E 2810/4885MAPK1 3171/4885CHUK 3243/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.