Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK2 | Q92630 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CCR8 | P51685 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | TOP2A | P11388 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL74671 | 0.79 | POLB (0.45) | TP53MAPTCCR8GPR119NAMPT | |
| SCHEMBL2682211 | 0.78 | GPR119 (0.44) | TP53MAPTCCR8GPR119 | |
| SCHEMBL1462914 | 0.77 | GPR119 (0.42) | TP53MAPTCCR8GPR119 | |
| SCHEMBL1463332 | 0.76 | MAPT (0.42) | TP53MAPTGPR119THRB | |
| SCHEMBL4187820 | 0.76 | HPGDS (0.43) | DYRK2MAPTKEAP1NFE2L2GPR119 | |
| SCHEMBL952678 | 0.76 | MEN1 (0.47) | MAPT | |
| SCHEMBL13852007 | 0.76 | MCHR1 (0.37) | — | |
| SCHEMBL13852006 | 0.75 | GSK3A (0.36) | — | |
| SCHEMBL955829 | 0.75 | GPR6 (0.52) | MAPT | |
| SCHEMBL14239639 | 0.73 | GPR119 (0.50) | MAPTGPR119NAMPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140179921-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2014-06-26 | — | — | US | disclosed |
| US-20130197029-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2013-08-01 | — | — | US | disclosed |
| US-8338443-B2 | Chemical compounds | SYNGENTA CROP PROTECTION LLC (US) | 2012-12-25 | — | — | US | disclosed |
| US-20090118295-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC (US) | 2009-05-07 | — | — | US | disclosed |
| EP-1965651-A2 | CHEMICAL COMPOUNDS | Syngeta Participations AG (CH) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007072143-A2 | CHEMICAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2007-06-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130197029-A1 | CHEMICAL COMPOUNDS | MRM1, H1-0, RO60 | DYRK2 2819/4885TP53 3421/4885MAPT 3827/4885 |
| US-20140179921-A1 | CHEMICAL COMPOUNDS | H1-0, REL, ZYX | DYRK2 1970/4885TP53 724/4885MAPT 4018/4885 |
| US-20090118295-A1 | CHEMICAL COMPOUNDS | MRM1, MNS1, CHRM1 | DYRK2 2524/4885TP53 3918/4885MAPT 4012/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.