Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.31 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4023097 | 0.81 | APLNR (0.35) | APLNRALDH1A1 | |
| SCHEMBL3946528 | 0.80 | APLNR (0.34) | APLNRHDAC6NTRK1 | |
| SCHEMBL4021434 | 0.79 | HDAC6 (0.32) | APLNRHDAC6 | |
| SCHEMBL4030776 | 0.79 | APLNR (0.34) | APLNRNTRK1 | |
| SCHEMBL1439307 | 0.76 | HDAC6 (0.30) | HDAC6 | |
| SCHEMBL1693207 | 0.76 | HDAC6 (0.30) | HDAC6 | |
| SCHEMBL3015031 | 0.76 | HDAC6 (0.30) | HDAC6 | |
| SCHEMBL4019567 | 0.76 | HDAC6 (0.30) | HDAC6 | |
| SCHEMBL346024 | 0.76 | HDAC6 (0.41) | APLNRHDAC6NTRK1ALK | |
| SCHEMBL3238364 | 0.76 | HDAC6 (0.41) | APLNRHDAC6NTRK1ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009016410-A2 | CHEMICAL COMPOUNDS 831 | ASTRAZENECA AB (SE) | 2009-02-05 | — | — | WO | disclosed |