Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 6/20 | 0.40 |
| ▸ | PPARD | Q03181 | 3/20 | 0.40 |
| ▸ | PPARG | P37231 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ACLY | P53396 | 2/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | PTGES | O14684 | 2/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4192840 | 0.89 | NR4A2 (0.44) | BCL2NR4A2PPARAPPARGMEN1 | |
| SCHEMBL4187130 | 0.88 | BCL2 (0.47) | BCL2NR4A2NPC1PPARAPPARD | |
| SCHEMBL4186598 | 0.84 | PPARA (0.56) | PPARAPPARDPPARGKMT2A | |
| SCHEMBL3381537 | 0.81 | BCL2 (0.43) | BCL2NR4A2NPC1MEN1KMT2A | |
| SCHEMBL4194987 | 0.76 | NR4A2 (0.46) | BCL2NR4A2MEN1KMT2AACLY | |
| SCHEMBL4191222 | 0.75 | PPARG (0.46) | PPARAPPARDPPARG | |
| SCHEMBL4187136 | 0.74 | PPARG (0.47) | NR4A2PPARAPPARDPPARGPTGES | |
| SCHEMBL4192083 | 0.71 | PPARA (0.59) | PPARAPPARDPPARGKMT2A | |
| SCHEMBL11468433 | 0.71 | OPRK1 (0.45) | PPARAPPARGMEN1KMT2A | |
| SCHEMBL3384706 | 0.70 | F10 (0.43) | BCL2NR4A2NPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1572180-B1 | USE OF ALPHA-PHENYLTHIOCARBOXYLIC ACIDS WITH SERUM-GLUCOSE-LOWERING AND SERUM-LIPID-LOWERING ACTIVITY | SIGMA TAU IND FARMACEUTI (IT) | 2009-02-25 | — | — | EP | claimed |