Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 14/20 | 0.56 |
| ▸ | PPARD | Q03181 | 10/20 | 0.56 |
| ▸ | PPARG | P37231 | 8/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4192083 | 0.86 | PPARA (0.59) | PPARAPPARDPPARGKMT2AATM | |
| SCHEMBL4187136 | 0.86 | PPARG (0.47) | PPARAPPARDPPARGFFAR1 | |
| SCHEMBL4184977 | 0.84 | BCL2 (0.47) | PPARAPPARDPPARGKMT2A | |
| SCHEMBL4191222 | 0.83 | PPARG (0.46) | PPARAPPARDPPARGFFAR1 | |
| SCHEMBL11468433 | 0.82 | OPRK1 (0.45) | PPARAPPARGKMT2ALMNAL3MBTL1 | |
| SCHEMBL3384312 | 0.80 | PPARA (0.51) | PPARAPPARDPPARGKMT2AATM | |
| SCHEMBL3383238 | 0.73 | PPARG (0.49) | PPARAPPARDPPARGFFAR1 | |
| SCHEMBL4192840 | 0.73 | NR4A2 (0.44) | PPARAPPARGKMT2A | |
| SCHEMBL4374627 | 0.72 | NR4A2 (0.71) | PPARAPPARDPPARGFFAR1TAAR1 | |
| SCHEMBL4191214 | 0.72 | ADAM17 (0.43) | PPARAPPARDPPARGFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1572180-B1 | USE OF ALPHA-PHENYLTHIOCARBOXYLIC ACIDS WITH SERUM-GLUCOSE-LOWERING AND SERUM-LIPID-LOWERING ACTIVITY | SIGMA TAU IND FARMACEUTI (IT) | 2009-02-25 | — | — | EP | claimed |