Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.44 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 2/20 | 0.42 |
| ▸ | BCL2 | P10415 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | ACLY | P53396 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HPD | P32754 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4194987 | 0.89 | NR4A2 (0.46) | NR4A2NR4A1NR4A3F10BCL2 | |
| SCHEMBL4184977 | 0.89 | BCL2 (0.47) | NR4A2BCL2MEN1KMT2AACLY | |
| SCHEMBL4187136 | 0.86 | PPARG (0.47) | NR4A2SIRT2PPARGPPARA | |
| SCHEMBL3384706 | 0.82 | F10 (0.43) | NR4A2NR4A1NR4A3F10BCL2 | |
| SCHEMBL4191214 | 0.77 | ADAM17 (0.43) | KDM4EPPARGPPARA | |
| SCHEMBL4187130 | 0.76 | BCL2 (0.47) | NR4A2NR4A1NR4A3BCL2MEN1 | |
| SCHEMBL6066388 | 0.74 | NR4A2 (0.76) | NR4A2NR4A1NR4A3F10KMT2A | |
| SCHEMBL3383238 | 0.74 | PPARG (0.49) | NR4A2SIRT2PPARGPPARA | |
| SCHEMBL4186598 | 0.73 | PPARA (0.56) | KMT2APPARGPPARA | |
| SCHEMBL4191237 | 0.72 | PPARG (0.45) | MEN1KMT2AMAPTPKMPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1572180-B1 | USE OF ALPHA-PHENYLTHIOCARBOXYLIC ACIDS WITH SERUM-GLUCOSE-LOWERING AND SERUM-LIPID-LOWERING ACTIVITY | SIGMA TAU IND FARMACEUTI (IT) | 2009-02-25 | — | — | EP | claimed |