Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 8/20 | 0.47 |
| ▸ | PPARA | Q07869 | 6/20 | 0.47 |
| ▸ | PPARD | Q03181 | 5/20 | 0.47 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 4/20 | 0.40 |
| ▸ | MAOA | P21397 | 3/20 | 0.40 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3383238 | 0.88 | PPARG (0.49) | PPARGPPARAPPARDSIRT2FFAR1 | |
| SCHEMBL4186598 | 0.86 | PPARA (0.56) | PPARGPPARAPPARDFFAR1 | |
| SCHEMBL4192840 | 0.86 | NR4A2 (0.44) | PPARGPPARASIRT2NR4A2 | |
| SCHEMBL4191214 | 0.86 | ADAM17 (0.43) | PPARGPPARAPPARDFFAR1SLC13A5 | |
| SCHEMBL3383701 | 0.81 | SIRT2 (0.47) | PPARGPPARAPPARDSIRT2FFAR1 | |
| SCHEMBL4193294 | 0.77 | PPARG (0.52) | PPARGPPARAPPARDSIRT2FFAR1 | |
| SCHEMBL4191222 | 0.75 | PPARG (0.46) | PPARGPPARAPPARDFFAR1SLC13A5 | |
| SCHEMBL4191237 | 0.74 | PPARG (0.45) | PPARGPPARAPPARD | |
| SCHEMBL4184977 | 0.74 | BCL2 (0.47) | PPARGPPARAPPARDNR4A2PTGES | |
| SCHEMBL4194987 | 0.74 | NR4A2 (0.46) | NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1572180-B1 | USE OF ALPHA-PHENYLTHIOCARBOXYLIC ACIDS WITH SERUM-GLUCOSE-LOWERING AND SERUM-LIPID-LOWERING ACTIVITY | SIGMA TAU IND FARMACEUTI (IT) | 2009-02-25 | — | — | EP | claimed |