Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 6/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.68 |
| ▸ | CYP1B1 | Q16678 | 6/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.68 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.68 |
| ▸ | MAPT | P10636 | 6/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | APP | P05067 | 1/20 | 0.56 |
| ▸ | GSK3B | P49841 | 1/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.55 |
| ▸ | TUBB | P07437 | 1/20 | 0.55 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.55 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3664956 | 1.00 | CYP1A1 (0.68) | CYP1A1CYP1A2CYP1B1CYP3A4CYP2D6 | |
| Wr-190433 SCHEMBL6180067 | 0.85 | TUBB4A (0.66) | CYP1B1CYP3A4MAPTALDH1A1LMNA | |
| Wr-190433 SCHEMBL30880222 | 0.85 | TUBB4A (0.66) | CYP1B1CYP3A4MAPTALDH1A1LMNA | |
| Wr-190433 SCHEMBL29870441 | 0.85 | TUBB4A (0.66) | CYP1B1CYP3A4MAPTALDH1A1LMNA | |
| Wr-190433 SCHEMBL977482 | 0.85 | TUBB4A (0.66) | CYP1B1CYP3A4MAPTALDH1A1LMNA | |
| SCHEMBL15882450 | 0.83 | TUBB4A (0.72) | CYP1B1MAPTALDH1A1LMNAKMT2A | |
| SCHEMBL15882451 | 0.83 | TUBB4A (0.72) | CYP1B1MAPTALDH1A1LMNAKMT2A | |
| SCHEMBL10376888 | 0.81 | HSP90AA1 (0.55) | CYP1B1MAPTALDH1A1LMNAKMT2A | |
| SCHEMBL10376889 | 0.81 | HSP90AA1 (0.55) | CYP1B1MAPTALDH1A1LMNAKMT2A | |
| SCHEMBL9503680 | 0.81 | CYP1B1 (1.00) | CYP1A1CYP1A2CYP1B1CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2242742-B1 | PYRIDINE DERIVATIVES | NOVARTIS AG (CH) | 2015-12-02 | — | — | EP | disclosed |
| US-8343966-B2 | Organic compounds | NOVARTIS AG (CH) | 2013-01-01 | — | — | US | disclosed |
| US-20090215776-A1 | Organic compounds | ADCOCK CLAIRE | 2009-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090215776-A1 | Organic compounds | REN, RXFP1, MYLK | CYP1A1 339/4885CYP1A2 616/4885CYP1B1 277/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.