Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.40 |
| ▸ | RARB | P10826 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.38 |
| ▸ | FEN1 | P39748 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | ERN1 | O75460 | 1/20 | 0.37 |
| ▸ | APC | P25054 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12437027 | 0.89 | RARB (0.55) | SMN1; SMN2ALDH1A1MAPK1TSHRRARB | |
| SCHEMBL2913907 | 0.89 | RARB (0.55) | SMN1; SMN2ALDH1A1MAPK1TSHRRARB | |
| SCHEMBL16810689 | 0.88 | ALDH1A1 (0.51) | SMN1; SMN2ALDH1A1MAPK1TSHRCD274 | |
| SCHEMBL2918327 | 0.88 | ALDH1A1 (0.60) | SMN1; SMN2ALDH1A1MAPK1TSHRHRH3 | |
| SCHEMBL2914899 | 0.82 | ALDH1A1 (0.49) | SMN1; SMN2ALDH1A1MAPK1TSHRCD274 | |
| SCHEMBL2914565 | 0.77 | ALDH1A1 (0.56) | SMN1; SMN2ALDH1A1MAPK1TSHRHRH3 | |
| SCHEMBL306032 | 0.76 | ALDH1A1 (0.65) | SMN1; SMN2ALDH1A1MAPK1TSHRHRH3 | |
| SCHEMBL2917604 | 0.75 | ALDH1A1 (0.63) | SMN1; SMN2ALDH1A1MAPK1TSHRHRH3 | |
| SCHEMBL13657327 | 0.74 | THRA (0.58) | SMN1; SMN2ALDH1A1MAPK1TSHRRARB | |
| SCHEMBL8070009 | 0.74 | ALDH1A1 (0.62) | SMN1; SMN2ALDH1A1MAPK1TSHRHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009125021-A1 | STRUCTURED FILMS WITH A CONTROLLED TILTED MOLECULAR ORIENTATION AND SHAPE USING A DICHROIC PHOTOINITIATOR | STICHTING DUTCH POLYMER INSTITUTE (NL) | 2009-10-15 | — | — | WO | disclosed |
| EP-2108691-A1 | Structured films with a controlled tilted molecular orientation and shape using a dichroic photoinitiator. | Stichting Dutch Polymer Institute (NL) | 2009-10-14 | — | — | EP | disclosed |
| WO-2006059895-A1 | SWITCHABLE NARROW BAND REFLECTORS PRODUCED IN A SINGLE CURING STEP | STICHTING DUTCH POLYMER INSTITUTE (NL) | 2006-06-08 | — | — | WO | disclosed |