SCHEMBL69953

SCHEMBL69953

O=C(Oc1ccccc1)c1ccc2cc(C(=O)Oc3ccccc3)ccc2c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.62
ALDH1A1 P00352 3/20 0.62
KMT2A Q03164 5/20 0.61
TDP1 Q9NUW8 4/20 0.61
MEN1 O00255 3/20 0.61
NSD2 O96028 1/20 0.61
PARP10 Q53GL7 1/20 0.56
ALOX5 P09917 1/20 0.54
PRSS1 P07477 1/20 0.54
ACR P10323 1/20 0.54
TMPRSS15 P98073 1/20 0.54
CES2 O00748 1/20 0.52
CES1 P23141 1/20 0.52
KDM4E B2RXH2 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.51
MAPK1 P28482 1/20 0.51
HPGD P15428 1/20 0.50
ALOX15 P16050 1/20 0.50
HSD17B10 Q99714 1/20 0.50
CA12 O43570 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL418527 0.96 MAPT (0.68) MAPTALDH1A1KMT2ATDP1MEN1
SCHEMBL72201 0.96 MAPT (0.62) MAPTALDH1A1KMT2ATDP1MEN1
SCHEMBL10960357 0.94 MAPT (0.57) MAPTALDH1A1KMT2ATDP1MEN1
SCHEMBL29637878 0.94 MAPT (0.57) MAPTALDH1A1KMT2ATDP1MEN1
SCHEMBL6054705 0.91 KMT2A (0.62) MAPTALDH1A1KMT2ATDP1MEN1
SCHEMBL8666453 0.89 KMT2A (0.64) MAPTALDH1A1KMT2ATDP1MEN1
SCHEMBL14599179 0.88 MAPT (0.55) MAPTALDH1A1KMT2ATDP1MEN1
SCHEMBL20008705 0.88 PLAU (0.61) MAPTALDH1A1PARP10PRSS1ACR
SCHEMBL70034 0.87 PARP10 (0.70) MAPTALDH1A1KMT2ATDP1MEN1
SCHEMBL6574344 0.87 NSD2 (0.57) MAPTALDH1A1KMT2ATDP1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2714845-B1 LIQUID CRYSTAL BLOCK COPOLYMER AND METHODS OF MAKING AND USING THE SAME BOSTON SCIENT SCIMED INC (US) 2015-07-22 EP claimed
US-8497342-B2 Liquid crystal block copolymer and methods of making and using the same BOSTON SCIENTIFIC SCIMED, INC. (US) 2013-07-30 US claimed
US-20120309901-A1 LIQUID CRYSTAL BLOCK COPOLYMER AND METHODS OF MAKING AND USING THE SAME BOSTON SCIENTIFIC SCIMED, INC. (US) 2012-12-06 US claimed
WO-2012166260-A1 LIQUID CRYSTAL BLOCK COPOLYMER AND METHODS OF MAKING AND USING THE SAME BOSTON SCIENTIFIC SCIMED, INC. (US) 2012-12-06 WO claimed
EP-1490420-B1 METHOD FOR COPOLYESTERCARBONATE SYNTHESIS GEN ELECTRIC (US) 2007-08-01 EP claimed
CN-1286877-C Method for copolyestercarbonate synthesis GEN ELECTRIC (US) 2006-11-29 CN claimed
CN-1656141-A Method for copolyestercarbonate synthesis GEN ELECTRIC (US) 2005-08-17 CN claimed
EP-1490420-A1 METHOD FOR COPOLYESTERCARBONATE SYNTHESIS GENERAL ELECTRIC COMPANY (US) 2004-12-29 EP claimed
US-6812320-B2 PREPARING A HYDROXY-TERMINATED POLYESTER INTERMEDIATE; REACTING WITH PHOSGENE IN A REACTION MIXTURE COMPRISING WATER, A SUBSTANTIALLY WATER- IMMISCIBLE ORGANIC SOLVENT, AND A BASE TO PRODUCE BLOCK COPOLYESTERCARBONATE GENERAL ELECTRIC COMPANY 2004-11-02 US claimed
US-20030195325-A1 METHOD FOR COPOLYESTERCARBONATE SYNTHESIS GENERAL ELECTRIC COMPANY 2003-10-16 US claimed
WO-2003082949-A1 METHOD FOR COPOLYESTERCARBONATE SYNTHESIS GENERAL ELECTRIC COMPANY (US) 2003-10-09 WO claimed
JP-4266851-A None JP disclosed
CN-110591063-B Modified polyethylene naphthalate containing imide structure and preparation method thereof 沈阳建筑大学 2022-06-07 CN disclosed
CN-110591063-A Modified polyethylene naphthalate containing imide structure and preparation method thereof 沈阳建筑大学 2019-12-20 CN disclosed
EP-2714845-B1 LIQUID CRYSTAL BLOCK COPOLYMER AND METHODS OF MAKING AND USING THE SAME BOSTON SCIENT SCIMED INC (US) 2015-07-22 EP disclosed
US-4542203-A Method for producing branched aromatic polyesters SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-09-17 US disclosed
US-4451642-A Bis(aminoneopentyl) aromatics and polyamides derived therefrom E. I. DU PONT DE NEMOURS AND COMPANY (US) 1984-05-29 US disclosed
US-4107444-A INTERMEDIATES FOR POLYESTERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1978-08-15 US disclosed
US-4065431-A Thermally stable, rigid polyesters from aromatic dibasic acids and thermally stable, rigid diols E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-12-27 US disclosed
US-3972852-A Process for preparing aromatic polyesters from diphenols TEIJIN LIMITED (JA) 1976-08-03 US disclosed