SCHEMBL72201

SCHEMBL72201

O=C(Oc1ccccc1)c1ccc2ccc(C(=O)Oc3ccccc3)cc2c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.62
KMT2A Q03164 5/20 0.62
MEN1 O00255 4/20 0.62
TDP1 Q9NUW8 3/20 0.62
ALDH1A1 P00352 2/20 0.58
NSD2 O96028 1/20 0.58
CES2 O00748 1/20 0.53
CES1 P23141 1/20 0.53
PARP10 Q53GL7 1/20 0.53
ALOX5 P09917 1/20 0.51
PRSS1 P07477 1/20 0.51
ACR P10323 1/20 0.51
TMPRSS15 P98073 1/20 0.51
CASP3 P42574 1/20 0.50
SENP8 Q96LD8 1/20 0.50
SENP7 Q9BQF6 1/20 0.50
SENP6 Q9GZR1 1/20 0.50
MAPK1 P28482 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
KDM4E B2RXH2 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL418527 0.96 MAPT (0.68) MAPTKMT2AMEN1TDP1ALDH1A1
SCHEMBL69953 0.96 MAPT (0.62) MAPTKMT2AMEN1TDP1ALDH1A1
SCHEMBL29637878 0.91 MAPT (0.57) MAPTKMT2AMEN1TDP1ALDH1A1
SCHEMBL10960357 0.91 MAPT (0.57) MAPTKMT2AMEN1TDP1ALDH1A1
SCHEMBL6054705 0.87 KMT2A (0.62) MAPTKMT2AMEN1TDP1ALDH1A1
SCHEMBL6574344 0.87 NSD2 (0.57) MAPTKMT2AMEN1TDP1ALDH1A1
SCHEMBL8666453 0.85 KMT2A (0.64) MAPTKMT2AMEN1TDP1ALDH1A1
SCHEMBL14599179 0.84 MAPT (0.55) MAPTKMT2AMEN1TDP1ALDH1A1
SCHEMBL20008705 0.84 PLAU (0.61) MAPTALDH1A1PARP10PRSS1ACR
SCHEMBL28008944 0.84 NSD2 (0.54) MAPTKMT2AMEN1TDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed
EP-1526149-B1 Aromatic amide block copolymer and process of producing the same TOSOH CORP (JP) 2007-05-23 EP disclosed
US-7129314-B2 Aromatic amide block copolymer and process of producing the same TOSOH CORPORATION (JP) 2006-10-31 US disclosed
US-20050090639-A1 Aromatic amide block copolymer and process of producing the same TOSOH CORPORATION (JP) 2005-04-28 US disclosed
EP-1526149-A1 Aromatic amide block copolymer and process of producing the same Tosoh Corporation (JP) 2005-04-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 MAPT 1923/4885KMT2A 1042/4885MEN1 4831/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.