SCHEMBL6054705

SCHEMBL6054705

O=C(Oc1ccccc1)c1ccc2cc(O)ccc2c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 7/20 0.62
MEN1 O00255 6/20 0.62
NPC1 O15118 2/20 0.62
RAB9A P51151 1/20 0.62
CASP3 P42574 2/20 0.57
SENP8 Q96LD8 2/20 0.57
SENP7 Q9BQF6 2/20 0.57
SENP6 Q9GZR1 2/20 0.57
NSD2 O96028 1/20 0.57
ESR1 P03372 5/20 0.55
MAPT P10636 3/20 0.54
ALDH1A1 P00352 2/20 0.54
CLK1 P49759 1/20 0.53
DYRK1A Q13627 1/20 0.53
DYRK1B Q9Y463 1/20 0.53
TDP1 Q9NUW8 1/20 0.53
ESR2 Q92731 4/20 0.50
PKM P14618 1/20 0.49
PARP10 Q53GL7 1/20 0.49
CYP1A2 P05177 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14981363 0.92 KMT2A (0.61) KMT2AMEN1NPC1RAB9ACASP3
SCHEMBL777641 0.91 KMT2A (0.59) KMT2AMEN1NPC1RAB9ACASP3
SCHEMBL69953 0.91 MAPT (0.62) KMT2AMEN1NSD2MAPTALDH1A1
SCHEMBL768213 0.89 KMT2A (0.57) KMT2AMEN1NPC1RAB9ACASP3
SCHEMBL4132871 0.88 KMT2A (0.54) KMT2AMEN1NPC1RAB9ACASP3
SCHEMBL418527 0.87 MAPT (0.68) KMT2AMEN1NPC1RAB9ANSD2
SCHEMBL72201 0.87 MAPT (0.62) KMT2AMEN1CASP3SENP8SENP7
SCHEMBL18608268 0.87 KMT2A (0.68) KMT2AMEN1NPC1RAB9ACASP3
SCHEMBL7122242 0.87 KMT2A (0.66) KMT2AMEN1NPC1RAB9ACASP3
SCHEMBL23386312 0.86 KMT2A (0.66) KMT2AMEN1NPC1RAB9ACASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104478724-B 6-Hydroxy-2-naphthoic acid phenyl ester series coupler and synthetic method thereof Henan Academy of SciencesChemistry Institute Co., Ltd. (CN) 2016-04-13 CN claimed
CN-104478724-A 6-hydroxy-2-naphthoate series coupling agent and synthetic method thereof ZHENGZHOU GECKO SCIENT INC 2015-04-01 CN claimed
CN-104478724-B 6-Hydroxy-2-naphthoic acid phenyl ester series coupler and synthetic method thereof Henan Academy of SciencesChemistry Institute Co., Ltd. (CN) 2016-04-13 CN disclosed
CN-104478724-B 6-Hydroxy-2-naphthoic acid phenyl ester series coupler and synthetic method thereof Henan Academy of SciencesChemistry Institute Co., Ltd. (CN) 2016-04-13 CN disclosed
CN-104768914-A Method for producing 6,6'-(ethylenedioxy)di-2-naphthoic acid diester TEIJIN LTD 2015-07-08 CN disclosed
CN-104478724-A 6-hydroxy-2-naphthoate series coupling agent and synthetic method thereof ZHENGZHOU GECKO SCIENT INC 2015-04-01 CN disclosed
US-8759474-B2 Method for producing liquid crystal polyester SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-06-24 US disclosed
US-8383759-B2 Method for producing liquid crystal polyester SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-02-26 US disclosed
US-20120253060-A1 METHOD FOR PRODUCING LIQUID CRYSTAL POLYESTER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-10-04 US disclosed
US-20120253003-A1 METHOD FOR PRODUCING LIQUID CRYSTAL POLYESTER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-10-04 US disclosed
EP-1081173-B1 Process for producing aromatic liquid crystalline polyester and film thereof SUMITOMO CHEMICAL CO (JP) 2006-05-03 EP disclosed
EP-0367278-A2 A process for producing aromatic polyesters SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-05-09 EP disclosed
US-4920197-A Aromatic polyester POLYPLASTICS CO., LTD. (JP) 1990-04-24 US disclosed
US-4918154-A COPOLYMER OF P-HYDROXYBENZOIC ACID, 6-HYDROXYL-2-NAPHTHOIC ACID, HYDROQUINONE, RESORCINOL, TEREPHTHALIC ACID, AND ISOPHTHALIC ACID; MELT PROCESSABILITY, HEAT RESISTANCE POLYPLASTICS CO., LTD. (JP) 1990-04-17 US disclosed
US-4910284-A Aromatic polyester POLYPLASTICS CO., LTD. (JP) 1990-03-20 US disclosed
EP-0357079-A2 Process for producing aromatic polyesters SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-03-07 EP disclosed
EP-0337729-A2 Polyester resin exhibiting optical anisotropy in molten state and composition thereof POLYPLASTICS CO. LTD. (JP) 1989-10-18 EP disclosed
EP-0334619-A2 Polyester resin exhibiting anisotropy in molten state and composition thereof POLYPLASTICS CO. LTD. (JP) 1989-09-27 EP disclosed
US-4767830-A Process for preparation of copolyester POLYPLASTICS CO., LTD. (JP) 1988-08-30 US disclosed
EP-0261976-A2 Process for the preparation of copolyesters which show anisotropy when molten POLYPLASTICS CO. LTD. (JP) 1988-03-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120253060-A1 METHOD FOR PRODUCING LIQUID CRYSTAL POLYESTER PUF60, NCAPH, PARG KMT2A 1993/4885MEN1 2473/4885NPC1 1105/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.