SCHEMBL418539

SCHEMBL418539

Cc1cccc(S(=O)(=O)NN)c1

nearest known ligand 0.65

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.65
MEN1 O00255 2/20 0.56
ALDH1A1 P00352 3/20 0.53
FBP1 P09467 9/20 0.53
MAPT P10636 2/20 0.51
HPGD P15428 1/20 0.51
FLT1 P17948 1/20 0.50
FLT4 P35916 1/20 0.50
KDR P35968 1/20 0.50
EDNRA P25101 1/20 0.50
KDM4E B2RXH2 1/20 0.49
LMNA P02545 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL148204 0.85 CA2 (0.54) KMT2AMEN1ALDH1A1MAPTHPGD
SCHEMBL6920158 0.83 KMT2A (0.69) KMT2AMEN1ALDH1A1FBP1MAPT
SCHEMBL29547938 0.82 KMT2A (0.67) KMT2AMEN1ALDH1A1FBP1MAPT
SCHEMBL1087618 0.82 KMT2A (0.67) KMT2AMEN1ALDH1A1FBP1MAPT
SCHEMBL8224043 0.80 KMT2A (0.65) KMT2AMEN1ALDH1A1FBP1MAPT
SCHEMBL12520277 0.80 KMT2A (0.65) KMT2AMEN1ALDH1A1FBP1MAPT
SCHEMBL22446712 0.80 KMT2A (0.65) KMT2AMEN1ALDH1A1FBP1MAPT
SCHEMBL27784622 0.80 KMT2A (0.65) KMT2AMEN1ALDH1A1FBP1MAPT
SCHEMBL138127 0.79 KMT2A (0.58) KMT2AMEN1ALDH1A1MAPTHPGD
SCHEMBL11101389 0.79 PTGES2 (0.50) KMT2AMEN1FLT1FLT4KDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114944467-B Pole piece and battery comprising same 珠海冠宇电池股份有限公司 2024-06-25 CN claimed
CN-116496628-A Heat insulation composite material and preparation method and application thereof 百能(天津)能源科技有限公司 2023-07-28 CN claimed
CN-115873566-A Bridging plugging material for drilling fluid and preparation method thereof 中国石油天然气集团有限公司 2023-03-31 CN claimed
CN-114944467-A Pole piece and battery comprising same 珠海冠宇电池股份有限公司 2022-08-26 CN claimed
CN-112500051-B Novel energy-saving environment-friendly foamed light soil for roadbed and preparation method thereof 广东泰禾建设有限公司 2022-05-17 CN claimed
CN-111689883-B Synthetic method of diaryl sulfone compound 上海应用技术大学 2022-02-11 CN claimed
CN-108144456-B Preparation of polytetrafluoroethylene hollow fiber membrane, membrane contactor and application 中国科学院大连化学物理研究所 2021-06-04 CN claimed
CN-112500051-A Novel energy-saving environment-friendly foamed light soil for roadbed and preparation method thereof 广东泰禾建设有限公司 2021-03-16 CN claimed
CN-111689883-A Synthetic method of diaryl sulfone compound 上海应用技术大学 2020-09-22 CN claimed
EP-1320523-B1 BRANCHED CHAIN AMINO ACID-DEPENDENT AMINOTRANSFERASE INHIBITORS AND THEIR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES WARNER LAMBERT CO (US) 2005-06-22 EP claimed
US-20050004167-A1 Branched chain amino acid-dependent aminotransferase inhibitors and their use in the treatment of neurodegenerative diseases WARNER-LAMBERT COMPANY LLC 2005-01-06 US claimed
EP-1320523-A2 BRANCHED CHAIN AMINO ACID-DEPENDENT AMINOTRANSFERASE INHIBITORS AND THEIR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES Warner-Lambert Company LLC (US) 2003-06-25 EP claimed
WO-2002024672-A2 BRANCHED CHAIN AMINO ACID-DEPENDENT AMINOTRANSFERASE INHIBITORS AND THEIR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES WARNER-LAMBERT COMPANY LLC (US) 2002-03-28 WO claimed
US-4102884-A TREATING A 3,14-DIHYDROXY-CARDENOLIDE WITH OXYGEN AND N-BROMOACETAMIDE IN THE PRESENCE OF PLATINUM, THEN WITH ETHANEDITHIOL, RANEY NICKEL STEELE CHEMICALS CO. LTD. (CA) 1978-07-25 US claimed
CN-119569658-A Sulfonyl pyridazinone compound and preparation method and application thereof 华南师范大学 2025-03-07 CN disclosed
CN-118073019-B Intelligent power cable with moistureproof capability and preparation process 广州岭南电缆股份有限公司 2024-06-28 CN disclosed
CN-114944467-B Pole piece and battery comprising same 珠海冠宇电池股份有限公司 2024-06-25 CN disclosed
US-4134891-A 14-Functionalized 8,19-oxido steroids and processes for preparation thereof STEELE CHEMICALS CO. LTD. (CA) 1979-01-16 US disclosed
US-4123532-A ADMINISTERING A PYRAZOLO(1,5-C)QUINAZOLIN-5(6H)-ONE COMPOUND E. R. SQUIBB & SONS, INC. (US) 1978-10-31 US disclosed
US-4102884-A TREATING A 3,14-DIHYDROXY-CARDENOLIDE WITH OXYGEN AND N-BROMOACETAMIDE IN THE PRESENCE OF PLATINUM, THEN WITH ETHANEDITHIOL, RANEY NICKEL STEELE CHEMICALS CO. LTD. (CA) 1978-07-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050004167-A1 Branched chain amino acid-dependent aminotransferase inhibitors and their use in the treatment of neurodegenerative diseases BCAT1, BCAT2, ABAT KMT2A 911/4885MEN1 3229/4885ALDH1A1 642/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.