SCHEMBL138127

SCHEMBL138127

NNS(=O)(=O)c1cccc(S(=O)(=O)c2cccc(S(=O)(=O)NN)c2)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.58
SMN1; SMN2 Q16637 3/20 0.58
LMNA P02545 2/20 0.58
MEN1 O00255 2/20 0.58
MAPT P10636 2/20 0.58
KDM4E B2RXH2 2/20 0.58
NPC1 O15118 1/20 0.58
HPGD P15428 1/20 0.58
RAB9A P51151 1/20 0.58
CASP6 P55212 1/20 0.48
GFER P55789 1/20 0.48
CA2 P00918 2/20 0.48
CA1 P00915 1/20 0.48
ALDH1A1 P00352 4/20 0.44
TSHR P16473 1/20 0.44
PKM P14618 1/20 0.43
GAA P10253 2/20 0.42
HTT P42858 2/20 0.42
CYP1A2 P05177 1/20 0.42
HTR6 P50406 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL148204 0.93 CA2 (0.54) KMT2ASMN1; SMN2LMNAMEN1MAPT
SCHEMBL18261208 0.86 SMN1; SMN2 (0.49) KMT2ASMN1; SMN2LMNAMEN1MAPT
SCHEMBL10665074 0.83 TSHR (0.57) KMT2ASMN1; SMN2LMNAMEN1MAPT
SCHEMBL11101389 0.83 PTGES2 (0.50) KMT2AMEN1CASP6GFERCA2
SCHEMBL11406378 0.81 LMNA (0.63) KMT2ASMN1; SMN2LMNACA2CA1
(Phenylsulfonyl)Benzene SCHEMBL28304808 0.80 HTR6 (0.64) KMT2ASMN1; SMN2LMNAMEN1KDM4E
SCHEMBL422145 0.79 GBA1 (0.53) KMT2AMEN1CASP6GFERCA2
SCHEMBL418539 0.79 KMT2A (0.65) KMT2ASMN1; SMN2LMNAMEN1MAPT
SCHEMBL6484439 0.79 PGR (0.61) LMNAMAPTPKM
SCHEMBL420249 0.79 ATM (0.53) KMT2AMEN1CASP6GFERPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1387 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117866314-B Polyolefin resin foam sheet, adhesive tape, display module, and electronic product 湖北祥源高新科技有限公司 2024-05-31 CN claimed
CN-117866314-A Polyolefin resin foam sheet, adhesive tape, display module, and electronic product 湖北祥源高新科技有限公司 2024-04-12 CN claimed
WO-2024008543-A1 METHOD FOR BONDING PARTS WITH REDUCED READ-THROUGH DEFORMATION SIKA TECHNOLOGY AG (CH) 2024-01-11 WO claimed
EP-4303251-A1 METHOD FOR BONDING PARTS WITH REDUCED READ-THROUGH DEFORMATION Sika Technology AG (CH) 2024-01-10 EP claimed
EP-4110861-B1 FIRE-RESISTANT ARTICLES AND STRUCTURES NMC SA (BE) 2023-10-11 EP claimed
US-20230279214-A1 FOAMABLE ACRYLIC COMPOSITION ARKEMA FRANCE (FR) 2023-09-07 US claimed
EP-2948512-B1 FOAMED HOT MELT ADHESIVE AND USE THEREOF HENKEL AG & CO KGAA (DE) 2023-07-05 EP claimed
EP-4110861-A1 FIRE-RESISTANT ARTICLES AND STRUCTURES NMC S.A. (BE) 2023-01-04 EP claimed
EP-3717554-A1 FOAMABLE ACRYLIC COMPOSITION Arkema, Inc. (US) 2020-10-07 EP claimed
US-20200282689-A1 MULTI-LAYER FLUOROPOLYMER FOAM STRUCTURE ARKEMA INC (US) 2020-09-10 US claimed
US-20030123994-A1 THERMOLYSIS REACTION ACTUATING PUMP INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE 2003-07-03 US claimed
US-6531546-B2 Roll and extrusion processability, surface appearance and adhesiveness, produces vulcanized rubber exhibiting excellent mechanical characteristics and good low and high temperature properties JSR CORPORATION (JP) 2003-03-11 US claimed
US-5663210-A CONTAINING A COPOLYMER OF ETHYLENE, A GLYCIDYL ESTER OR ETHER AND ANOTHER UNSATURATED ESTER, A CARBOXYLIC ACID AND A FOAMING AGENT SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-09-02 US claimed
EP-0447817-B1 Process for preparing cellular polyurethane articles by sintering BASF AG (DE) 1995-08-02 EP claimed
US-5288549-A Composite element comprising a top layer and a base layer of thermoplastic polyurethanes, its preparation, and its use BASF AKTIENGESELLSCHAFT (DE) 1994-02-22 US claimed
EP-0157690-B1 PRODUCT FOR REINFORCING A FLAT TEXTILE SURFACE, PROCESS FOR ITS MANUFACTURE AND APPLICATIONS Centre Technique Industriel dit: INSTITUT TEXTILE DE FRANCE (FR) 1988-10-26 EP claimed
US-4559190-A Process for the production of expanded reticulated polyethylene AGIP PETROLI S.P.A. (IT) 1985-12-17 US claimed
EP-0138265-A2 Process for the production of expanded reticulated polyethylene AGIP PETROLI S.p.A. (IT) 1985-04-24 EP claimed
US-4255371-A Process for producing olefinic resin foams JAPAN STYRENE PAPER CORPORATION (JP) 1981-03-10 US claimed
US-3966651-A Process for the production of fine-cell polyolefin foams BAYER AKTIENGESELLSCHAFT (DT) 1976-06-29 US claimed