SCHEMBL4185589

SCHEMBL4185589

SC[Si](c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.41
ESR1 P03372 1/20 0.32
ESR2 Q92731 1/20 0.32
CALM1 P0DP23 1/20 0.32
ANPEP P15144 1/20 0.31
ALDH1A1 P00352 2/20 0.31
TSHR P16473 1/20 0.31
HDAC3 O15379 1/20 0.30
HDAC4 P56524 1/20 0.30
HDAC1 Q13547 1/20 0.30
HDAC7 Q8WUI4 1/20 0.30
HDAC2 Q92769 1/20 0.30
HDAC10 Q969S8 1/20 0.30
HDAC11 Q96DB2 1/20 0.30
HDAC8 Q9BY41 1/20 0.30
HDAC6 Q9UBN7 1/20 0.30
HDAC9 Q9UKV0 1/20 0.30
HDAC5 Q9UQL6 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4193671 0.78 IDO1 (0.38) IDO1ESR1ESR2ALDH1A1TSHR
SCHEMBL10402043 0.75 CALM1 (0.35) IDO1ESR1ESR2CALM1ALDH1A1
SCHEMBL7139123 0.74 HDAC3 (0.39) IDO1ALDH1A1TSHRHDAC3HDAC4
SCHEMBL4194521 0.72 HDAC3 (0.42) IDO1ALDH1A1TSHRHDAC3HDAC4
SCHEMBL6833296 0.72 MAPT (0.44) IDO1ESR1ESR2TSHR
SCHEMBL3235645 0.71 ALDH1A1 (0.33) ESR1ESR2CALM1ALDH1A1TSHR
SCHEMBL874225 0.71 MAPT (0.33) ESR1ESR2CALM1ALDH1A1TSHR
SCHEMBL3889977 0.71 TP53 (0.41) ESR1ESR2ALDH1A1TSHR
SCHEMBL1710603 0.71 TSHR (0.41) IDO1ESR1ESR2CALM1ALDH1A1
SCHEMBL8986065 0.69 TDP1 (0.37) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6507049-B1 Encapsulants for solid state devices GENERAL ELECTRIC COMPANY 2003-01-14 US claimed
WO-2002019440-A1 ENCAPSULANTS FOR SOLID STATE DEVICES GENERAL ELECTRIC COMPANY (US) 2002-03-07 WO claimed
US-5145889-A For light-emitting diodes KABUSHIKI KAISHA TOSHIBA (JP) 1992-09-08 US claimed
US-20090121251-A1 Siloxane-hydantoin copolymer, optoelectronic device encapsulated therewith and method LUMINATION LLC 2009-05-14 US disclosed
US-20080160317-A1 Optoelectronic device GELCORE LLC 2008-07-03 US disclosed
US-20080001140-A1 Optoelectronic device GELCORE LLC 2008-01-03 US disclosed
US-20070299162-A1 Light emitting semiconductor and encapsulant is made from nano-functionalized zirconia; silicone epoxy, epoxy isocyanurate and succinic anhydride, dodecenylsuccinic anhydride, phthalic anhydride curing agent; ancillary curing catalyst, cure modifier, coupling agent, UV, thermal stabilizer GELCORE LLC 2007-12-27 US disclosed
US-20070295983-A1 Optoelectronic device GELCORE LLC 2007-12-27 US disclosed
US-20070295956-A1 Optoelectronic device GELCORE LLC 2007-12-27 US disclosed
EP-1408087-B1 Epoxy-polysiloxane resin compositions, solid state devices encapsulated therewith and method GEN ELECTRIC (US) 2007-10-10 EP disclosed
US-7144763-B2 light emitting diode; curable silicone with pendant epoxy groups, a hydroxyl-containing compound or silicone, anhydride curing agent, ancillary curing catalyst; radiation transparent, UV stability, clear; packaging GENERAL ELECTRIC COMPANY (US) 2006-12-05 US disclosed
US-6617401-B2 Free of halogen, and contains at least one cure modifier, and, optionally at least one ancillary curing catalyst; for encapsulating a solid state device GENERAL ELECTRIC COMPANY 2003-09-09 US disclosed
US-6617400-B2 Free of halogen, and contains at least one cure modifier, and, optionally at least one ancillary curing catalyst; for encapsulating a solid state device GENERAL ELECTRIC COMPANY 2003-09-09 US disclosed
US-20030071368-A1 Epoxy resin compositions, solid state devices encapsulated therewith and method GENERAL ELECTRIC COMPANY 2003-04-17 US disclosed
US-20030071366-A1 For encapsulating a solid state device, such as a light emitting diode GENERAL ELECTRIC COMPANY 2003-04-17 US disclosed
US-20030071367-A1 Epoxy resin compositions, solid state devices encapsulated therewith and method GENERAL ELECTRIC COMPANY 2003-04-17 US disclosed
EP-1285938-A1 Epoxy resin encapsulation compositions GENERAL ELECTRIC COMPANY (US) 2003-02-26 EP disclosed
EP-1285939-A1 Epoxy resin compositions and solid state devices encapsulated therewith GENERAL ELECTRIC COMPANY (US) 2003-02-26 EP disclosed
US-6507049-B1 Encapsulants for solid state devices GENERAL ELECTRIC COMPANY 2003-01-14 US disclosed
US-5145889-A For light-emitting diodes KABUSHIKI KAISHA TOSHIBA (JP) 1992-09-08 US disclosed