Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.35 |
| ▸ | MGAM | O43451 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9217667 | 0.78 | MAPT (0.47) | MAPTESR1ESR2NR1H2NR1H3 | |
| SCHEMBL4346243 | 0.77 | MGAM (0.40) | MAPTESR1ESR2IDO1NR1H2 | |
| SCHEMBL9226507 | 0.76 | MAPT (0.45) | MAPTESR1ESR2NR1H2NR1H3 | |
| SCHEMBL8973056 | 0.75 | MAPT (0.41) | MAPTESR1ESR2NR1H2NR1H3 | |
| SCHEMBL4201225 | 0.75 | HDAC3 (0.39) | MAPTESR1ESR2IDO1NR1H2 | |
| SCHEMBL25284860 | 0.74 | MAPT (0.44) | MAPTESR1ESR2NR1H2NR1H3 | |
| SCHEMBL852172 | 0.74 | MAPT (0.44) | MAPTESR1ESR2NR1H2NR1H3 | |
| SCHEMBL18084487 | 0.74 | MGAM (0.44) | MAPTESR1ESR2NR1H2NR1H3 | |
| SCHEMBL9712158 | 0.74 | MAPT (0.48) | MAPTESR1ESR2NR1H2NR1H3 | |
| SCHEMBL3614652 | 0.74 | MAPT (0.48) | MAPTESR1ESR2NR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1448629-A1 | IMPROVED OLEFIN POLYMERIZATION PROCESS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2004-08-25 | — | — | EP | disclosed |
| US-6780949-B2 | HOMO OR COPOLYMERIZING AN OLEFIN COMPOUND BY EMPLOYING A COMPLEX OF A GROUP 8, 9, OR 10 TRANSITION METAL WITH A BIDENTATE LIGAND AS PART OF THE CATALYST SYSTEM ARE IMPROVED BY ADDING TO THE POLYMERIZATION A SILICON COMPOUND | E. I. DU PONT DE NEMOURS AND COMPANY | 2004-08-24 | — | — | US | disclosed |
| US-20030130450-A1 | Olefin polymerization process | E. I. DU PONT DE NEMOURS AND COMPANY | 2003-07-10 | — | — | US | disclosed |
| WO-2003044067-A1 | IMPROVED OLEFIN POLYMERIZATION PROCESS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2003-05-30 | — | — | WO | disclosed |
| EP-0437784-B1 | Imidazolidine derivatives, process for producing the same and pesticides containing the same | ISHIHARA SANGYO KAISHA (JP) | 1996-04-17 | — | — | EP | disclosed |
| US-5256674-A | Inecticides, miticides, nematocides | ISHIHARA SANGYO KAISHA LTD. (JP) | 1993-10-26 | — | — | US | disclosed |
| EP-0437784-A1 | Imidazolidine derivatives, process for producing the same and pesticides containing the same | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1991-07-24 | — | — | EP | disclosed |