Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
| ▸ | CASP1 | P29466 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.52 |
| ▸ | NOS1 | P29475 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 2/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11807012 | 0.89 | CYP2C19 (0.50) | ALDH1A1HPGDALOX15ALOX12CASP1 | |
| SCHEMBL9976789 | 0.88 | TDP1 (0.55) | ALDH1A1HPGDALOX15ALOX12CASP1 | |
| SCHEMBL4262475 | 0.88 | TDP1 (0.55) | ALDH1A1HPGDALOX15ALOX12CASP1 | |
| SCHEMBL11446638 | 0.87 | TP53 (0.46) | ALDH1A1HPGDALOX15ALOX12CASP1 | |
| SCHEMBL779766 | 0.86 | NOS1 (0.55) | ALDH1A1HPGDALOX15ALOX12CASP1 | |
| SCHEMBL775359 | 0.84 | MAOA (0.56) | HTR2ANOS1MAOAMAOBSIGMAR1 | |
| SCHEMBL10664294 | 0.84 | CYP1A2 (0.46) | ALDH1A1HPGDALOX15ALOX12CASP1 | |
| SCHEMBL28372919 | 0.82 | HPGD (0.50) | ALDH1A1HPGDALOX15ALOX12CASP1 | |
| SCHEMBL19969981 | 0.82 | AOC3 (0.43) | ALDH1A1HPGDALOX15ALOX12CASP1 | |
| SCHEMBL577806 | 0.81 | CYP1A2 (0.76) | ALDH1A1HPGDALOX15ALOX12CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113122058-A | Preparation method of ink and quantum dot film | TCL集团股份有限公司 | 2021-07-16 | — | — | CN | claimed |
| US-20030176512-A1 | Asymmetric disulfides and methods of using same | PROLX PHARMACEUTICALS CORPORATION (CA) | 2003-09-18 | — | — | US | claimed |
| CN-114989050-A | Synthesis method of symmetric disulfide compound | 浙江大学衢州研究院 | 2022-09-02 | — | — | CN | disclosed |
| CN-113122058-A | Preparation method of ink and quantum dot film | TCL集团股份有限公司 | 2021-07-16 | — | — | CN | disclosed |
| CN-106278965-B | Aryl alkyl asymmetry over cure class compound and its synthetic method and application | 华东师范大学 | 2018-02-23 | — | — | CN | disclosed |
| CN-106278965-A | Aryl alkyl asymmetric over cure compounds and synthetic method thereof and application | 华东师范大学 | 2017-01-04 | — | — | CN | disclosed |
| CN-102612416-B | Silver-(conjugated compound) complex | SUMITOMO CHEMICAL CO | 2014-09-24 | — | — | CN | disclosed |
| CN-102612416-A | Silver-(conjugated compound) complex | SUMITOMO CHEMICAL CO | 2012-07-25 | — | — | CN | disclosed |
| WO-2009082686-A1 | COMPOSITIONS AND METHODS FOR USING ASYMMETRIC DISULFIDES | PROLX PHARMACEUTICALS CORP. (US) | 2009-07-02 | — | — | WO | disclosed |
| US-20080295260-A1 | Disulfide Dyes, Composition Comprising them and Method of Dyeing Hair | CIBA SPECIALTY CHEMICALS CORP. | 2008-12-04 | — | — | US | disclosed |
| EP-1786477-A2 | METHOD OF PRESELECTION PATIENTS FOR ANTI-VEGF, ANTI-HIF-1 OR ANTI-THIOREDOXIN THERAPY | Prolx Pharmaceuticals Corp. (US) | 2007-05-23 | — | — | EP | disclosed |
| EP-0883622-A1 | PROTON PUMP INHIBITOR | APOTEX INC. (CA) | 1998-12-16 | — | — | EP | disclosed |
| EP-0883606-A1 | PROCESS FOR SCAVENGING THIOLS | APOTEX INC. (CA) | 1998-12-16 | — | — | EP | disclosed |
| WO-1997031923-A1 | PROTON PUMP INHIBITOR | APOTEX INC. (CA) | 1997-09-04 | — | — | WO | disclosed |
| WO-1997031893-A1 | PROCESS FOR SCAVENGING THIOLS | APOTEX INC. (CA) | 1997-09-04 | — | — | WO | disclosed |
| EP-0781834-A2 | Lubricating oil composition | NIPPON OIL CO. LTD. (JP) | 1997-07-02 | — | — | EP | disclosed |
| EP-0022634-B1 | ACYLATED INDOLE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS AND DRUGS COMPRISING THEM | TEIJIN LIMITED (JP) | 1983-04-06 | — | — | EP | disclosed |
| EP-0022634-A1 | Acylated indole derivatives, processes for their preparation and pharmaceutical compositions and drugs comprising them | TEIJIN LIMITED (JP) | 1981-01-21 | — | — | EP | disclosed |
| US-4154840-A | Antihypertensive pipecolic acid derivatives | E. R. SQUIBB & SONS, INC. (US) | 1979-05-15 | — | — | US | disclosed |
| US-4105776-A | ANGIOTENSIN CONVERTING ENZYME INHIBITORS, HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1978-08-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080295260-A1 | Disulfide Dyes, Composition Comprising them and Method of Dyeing Hair | STS, CYP2S1, SQOR | ALDH1A1 203/4885HPGD 689/4885ALOX15 2344/4885 |
| US-20030176512-A1 | Asymmetric disulfides and methods of using same | PRDX3, PDIA5, PRDX5 | ALDH1A1 2098/4885HPGD 1245/4885ALOX15 1285/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.