Known targets — ChEMBL curated mechanism
CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8
The experimentally established mechanism targets of Triphosphate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | INPPL1 | O15357 | 4/20 | 0.40 |
| ▸ | INPP5A | Q14642 | 2/20 | 0.40 |
| ▸ | INPP5B | P32019 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA7 | P43166 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.35 |
| ▸ | BTN3A1 | O00481 | 2/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyrophosphoric Acid SCHEMBL4179033 | 0.89 | FDPS (0.59) | FDPSBLMTDP1BACE1INPPL1 | |
| SCHEMBL4181918 | 0.85 | INPPL1 (0.45) | FDPSBLMTDP1BACE1INPPL1 | |
| SCHEMBL4179021 | 0.84 | INPPL1 (0.48) | FDPSBLMTDP1BACE1INPPL1 | |
| Resorcinol SCHEMBL27885652 | 0.84 | CA12 (0.50) | FDPSBLMTDP1INPPL1INPP5A | |
| Triphosphate SCHEMBL18714 | 0.80 | FDPS (0.69) | FDPSBLMTDP1INPPL1INPP5A | |
| Triphosphate SCHEMBL15555988 | 0.80 | FDPS (0.69) | FDPSBLMTDP1INPPL1INPP5A | |
| SCHEMBL4181366 | 0.78 | FDPS (0.50) | FDPSBLMTDP1INPPL1INPP5A | |
| Triphosphate SCHEMBL25284822 | 0.76 | FDPS (0.64) | FDPSBLMTDP1BTN3A1 | |
| Triphosphate SCHEMBL3253186 | 0.76 | FDPS (0.64) | FDPSBLMTDP1BTN3A1 | |
| Triphosphate SCHEMBL9632051 | 0.76 | FDPS (0.64) | FDPSBLMTDP1BTN3A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090098589-A1 | Method | DUPONT NUTRITION BIOSCIENCES APS (DK) | 2009-04-16 | — | — | US | claimed |
| JP-2008545385-A | — | — | 2008-12-18 | — | — | JP | claimed |
| EP-1888771-A2 | METHOD FOR DETERMINING PHYTASE ACTIVITY | DANISCO A/S (DK) | 2008-02-20 | — | — | EP | claimed |
| WO-2006123254-A2 | METHOD FOR DETERMINING PHYTASE ACTIVITY | DANISCO A/S (DK) | 2006-11-23 | — | — | WO | claimed |
| CN-117222705-A | Thermosetting composition, method for producing molded article using same, and cured article | 出光兴产株式会社 | 2023-12-12 | — | — | CN | disclosed |
| CN-117178003-A | Thermosetting composition for injection molding, method for producing molded article using the composition, and cured article | 出光兴产株式会社 | 2023-12-05 | — | — | CN | disclosed |
| CN-117120494-A | Thermosetting composition, method for producing molded article using same, and cured article | 出光兴产株式会社 | 2023-11-24 | — | — | CN | disclosed |
| CN-117098787-A | Thermosetting composition for injection molding, method for producing molded article using the composition, and cured article | 出光兴产株式会社 | 2023-11-21 | — | — | CN | disclosed |
| US-20090098589-A1 | Method | DUPONT NUTRITION BIOSCIENCES APS (DK) | 2009-04-16 | — | — | US | disclosed |
| CN-101175861-A | Method | DANISCO (DK) | 2008-05-07 | — | — | CN | disclosed |
| EP-1888771-A2 | METHOD FOR DETERMINING PHYTASE ACTIVITY | DANISCO A/S (DK) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006123254-A2 | METHOD FOR DETERMINING PHYTASE ACTIVITY | DANISCO A/S (DK) | 2006-11-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090098589-A1 | Method | ALPL, PPA1, ITPA | FDPS 176/4885BLM 3653/4885TDP1 1661/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.